Multidisciplinary Training Program on Neuropsychiatry and Behavioral Disorders in

描述(由申请者提供)：我们计划提交一份提案，作为在玻利维亚、秘鲁和阿根廷发展可持续研究能力的R21奖项的后续和扩展。我们正在进行的南美和美国调查人员在神经精神病学和遗传学研究领域的培训方案侧重于影响南美洲土著社区的人的问题。该提案描述了阿根廷、玻利维亚、秘鲁、巴拉圭和美国调查人员在流行病学、遗传学和神经成像领域开展的一项为期五年的联合培训计划，以研究南美洲原住民中的主要精神疾病。该计划将建立在R21奖和K08奖支持下开发的现有研究培训机会的基础上。现有的研究项目招募、招募和保留了MD科学家、临床心理学家、遗传学家/统计学家和学历较低的卫生工作者，在与参与研究人员的指导关系中和定期合作中。我们将遴选属于成员国土著人口并能流利使用当地语言的医学博士和临床心理学家。该项目的实习生将在USF完成医学硕士学位(部分在网上，部分在校园内)，一个美国研究轮换，两个南美研究轮换，他们将可以选择在布宜诺斯艾利斯大学攻读博士学位的博士论文。选择这一选项的人将能够通过NEUFIN申请试点研究资金。我们的目标是扩大他们获得最先进研究经验的机会，并将这些经验带回他们的祖国，以解决主要的全球卫生问题。拟议的方案是多学科的，反映了了解神经、精神和行为障碍的复杂病因所需的广泛专业知识，这些疾病对全球疾病负担有很大影响。我们的目标是：1.在已经开始培训南美洲杰出的医生、心理学家、统计学家和遗传学家的基础上，为临床神经科学研究和人类遗传学提供长期的多学科培训。我们将通过提供(I)学徒模式下的导师制，(Ii)30个月的奖学金来完成南佛罗里达大学莫尔萨尼医学院的医学硕士学位，以及在哈佛医学院和华盛顿大学医学院的研究轮换，以及在Peruana Cayetano Heredia大学和布宜诺斯艾利斯大学的导师研究项目，(Iii)在布宜诺斯艾利斯大学开始博士论文的导师和试点资金，以实现这一目标。2.通过提供：(I)教师交流，(Ii)有美国研究人员参加的地区网络会议，(Iii)支持研究成果的出版，加强和丰富学术计划。3.实施战略，以增加区域和国际研究结构：(I)从多个地点招聘将返回本国机构的受训人员，(Ii)继续发展个人和多学科研究，(Iii)培训负责任地进行与文化相关但符合美国政府45CFR46准则的研究。4.通过在FIC/ARRA奖项的支持下开发的基于网络的电子通信工具，与其他Fogarty培训计划互动，以分享课程和培训经验，以增强我们的计划。

DESCRIPTION (provided by applicant): We plan to submit a proposal as a follow up and expansion of an R21 award to develop sustainable research capacity in Bolivia, Peru and Argentina. Our ongoing training program between South- American and US investigators in the areas of neuropsychiatric and genetics research focused on the problems affecting people from indigenous communities in South America. The proposal describes a five year joint training program between Argentina, Bolivia, Peru, Paraguay and US investigators in the areas of epidemiology, genetics and neuroimaging to study major psychiatric disorders amongst First Nations in South America. The program will build on the existing research training opportunities developed with the support of the R21 award and a K08 award. The existing research project has recruited, enrolled, and retained MD scientists, clinical psychologists, geneticists/statisticians and health workers with lower levels of academic education in mentorship relationships with participating investigators and in regular collaborative work. We will select MDs and clinical psychologists belonging to indigenous populations of the member countries and fluent in their native languages. Trainees from the program will complete a Master of Medical Sciences at USF (partly online, partly on campus), one US and two South American research rotations, and they will have the option to pursue a Ph.D. dissertation towards a doctoral degree at the Universidad de Buenos Aires. Those who elect this option will be able to apply for pilot research funding through NEUFIN. We aim to expand on their opportunity to gain state of the art research experience and bring that experience back to their home countries to address major global health problems. The proposed program is multidisciplinary and reflecting the wide range of expertise required for understanding the complex etiology of neuropsychiatric and behavioral disorders which contribute significantly to the global burden of disease. We aim to: 1. Build on the momentum already begun training outstanding physicians, psychologists, statisticians, and geneticists in South-America for long-term multidisciplinary training in clinica neurosciences research and human genetics. We will achieve this goal by providing (i) mentorship under the apprenticeship model, (ii) 30 month fellowships to complete a Master of Medical Sciences degree at University of South Florida Morsani College of Medicine and research rotations at Harvard Medical School and Washington University School of Medicine, as well as mentored research projects at Universidad Peruana Cayetano Heredia and Universidad de Buenos Aires, (iii) mentoring and pilot funding to start doctoral dissertations at Universidad de Buenos Aires. 2. Strengthen and enrich academic programs by providing: (i) faculty exchanges, (ii) regional networking meetings with participation of US researchers, (iii) support for publication of research results. 3. Implement strategies to increase the regional and international research structure by: (i) Recruitment of trainees from multiple sites who will retur to their home institutions, (ii) Continued growth of individual and multidisciplinary research studies, (iii) Training in the responsible conduct of research that is culturally relevant yet meet the guidelines of 45CFR46 of the US Government. 4. Interact with other Fogarty Training Programs via web-based electronic communication tools developed with the support of a FIC/ARRA award to share curriculum and training experiences to enhance our programs.