Multidisciplinary Training Program on Neuropsychiatry and Behavioral Disorders in

描述（由申请人提供）：我们计划提交一份提案，作为R21奖励的后续和扩展，以发展玻利维亚、秘鲁和阿根廷的可持续研究能力。我们正在进行的南美和美国研究人员之间的神经精神病学和遗传学研究领域的培训计划侧重于影响南美土著社区人民的问题。该提案描述了阿根廷、玻利维亚、秘鲁、巴拉圭和美国研究人员在流行病学、遗传学和神经影像学领域开展的为期五年的联合培训计划，以研究南美洲第一民族的主要精神疾病。该计划将以现有的研究培训机会为基础，在R21奖和K08奖的支持下开发。现有的研究项目通过与参与研究人员的师友关系和定期的合作工作，招募、招收和留住了学术教育水平较低的医学博士科学家、临床心理学家、遗传学家/统计学家和卫生工作者。我们将选择属于成员国土著居民并精通其母语的医学博士和临床心理学家。该项目的学员将在USF完成医学硕士学位（部分在线，部分在校），一次美国和两次南美研究轮转，他们将可以选择在布宜诺斯艾利斯大学攻读博士学位。选择此选项的人将能够通过NEUFIN申请试点研究资金。我们的目标是扩大他们获得最先进的研究经验的机会，并将这些经验带回他们的祖国，以解决重大的全球卫生问题。拟议的计划是多学科的，反映了理解神经精神和行为障碍的复杂病因所需的广泛专业知识，这些疾病对全球疾病负担有重大影响。我们的目标是：1；在南美已经开始培训优秀医生、心理学家、统计学家和遗传学家的势头的基础上，开展临床神经科学研究和人类遗传学方面的长期多学科培训。我们将通过以下方式实现这一目标：(i)在学徒模式下提供指导；（ii）提供30个月的研究金，用于在南佛罗里达大学莫尔萨尼医学院完成医学硕士学位，并在哈佛医学院和华盛顿大学医学院进行研究轮调，以及在秘鲁大学卡耶塔诺埃雷迪亚大学和布宜诺斯艾利斯大学进行指导研究项目。（三）指导和试点资金，开始在布宜诺斯艾利斯大学的博士论文。通过以下方式加强和丰富学术项目：(1)教员交流；(2)有美国研究人员参加的区域网络会议；(3)支持研究成果的发表。3. 实施战略，通过以下方式增加区域和国际研究结构：(i)从多个地点招聘将返回本国院校的学员；（ii）继续增加个人和多学科研究；（iii）培训负责任的研究行为，与文化相关，但符合美国政府45CFR46的指导方针。通过基于网络的电子通信工具与其他福格蒂培训计划进行互动，这些工具是在FIC/ARRA奖的支持下开发的，以分享课程和培训经验，以增强我们的计划。

DESCRIPTION (provided by applicant): We plan to submit a proposal as a follow up and expansion of an R21 award to develop sustainable research capacity in Bolivia, Peru and Argentina. Our ongoing training program between South- American and US investigators in the areas of neuropsychiatric and genetics research focused on the problems affecting people from indigenous communities in South America. The proposal describes a five year joint training program between Argentina, Bolivia, Peru, Paraguay and US investigators in the areas of epidemiology, genetics and neuroimaging to study major psychiatric disorders amongst First Nations in South America. The program will build on the existing research training opportunities developed with the support of the R21 award and a K08 award. The existing research project has recruited, enrolled, and retained MD scientists, clinical psychologists, geneticists/statisticians and health workers with lower levels of academic education in mentorship relationships with participating investigators and in regular collaborative work. We will select MDs and clinical psychologists belonging to indigenous populations of the member countries and fluent in their native languages. Trainees from the program will complete a Master of Medical Sciences at USF (partly online, partly on campus), one US and two South American research rotations, and they will have the option to pursue a Ph.D. dissertation towards a doctoral degree at the Universidad de Buenos Aires. Those who elect this option will be able to apply for pilot research funding through NEUFIN. We aim to expand on their opportunity to gain state of the art research experience and bring that experience back to their home countries to address major global health problems. The proposed program is multidisciplinary and reflecting the wide range of expertise required for understanding the complex etiology of neuropsychiatric and behavioral disorders which contribute significantly to the global burden of disease. We aim to: 1. Build on the momentum already begun training outstanding physicians, psychologists, statisticians, and geneticists in South-America for long-term multidisciplinary training in clinica neurosciences research and human genetics. We will achieve this goal by providing (i) mentorship under the apprenticeship model, (ii) 30 month fellowships to complete a Master of Medical Sciences degree at University of South Florida Morsani College of Medicine and research rotations at Harvard Medical School and Washington University School of Medicine, as well as mentored research projects at Universidad Peruana Cayetano Heredia and Universidad de Buenos Aires, (iii) mentoring and pilot funding to start doctoral dissertations at Universidad de Buenos Aires. 2. Strengthen and enrich academic programs by providing: (i) faculty exchanges, (ii) regional networking meetings with participation of US researchers, (iii) support for publication of research results. 3. Implement strategies to increase the regional and international research structure by: (i) Recruitment of trainees from multiple sites who will retur to their home institutions, (ii) Continued growth of individual and multidisciplinary research studies, (iii) Training in the responsible conduct of research that is culturally relevant yet meet the guidelines of 45CFR46 of the US Government. 4. Interact with other Fogarty Training Programs via web-based electronic communication tools developed with the support of a FIC/ARRA award to share curriculum and training experiences to enhance our programs.