Cardiovascular Disease among Asians and Pacific Islanders (CASPER)

亚洲人和太平洋岛民的心血管疾病 (CASPER)

• 批准号: 9309053
• 负责人: Stephen Paul Fortmann
• 金额: $ 83.95万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9309053
• 关键词: Acculturation; Age; American Heart Association; Asian Indian; Asians; Blood; Body mass index; California; Cardiovascular Diseases; Cause of Death; Chinese People; Classification; Clinical; Clinical Data; Data Reporting; Diet; Disease Outcome; Electronic Health Record; Epidemiology; Ethnic group; Filipino; Future; Geographic Locations; Growth; Hawaii; Hawaiian population; Health; Health Planning; Health behavior; Health system; Healthcare; Heart; Hypertension; Incidence; Individual; Institutes; Integrated Health Care Systems; Intervention; Japanese Population; Knowledge; Lung; Measures; Minority; Minority Groups; Modeling; Morbidity - disease rate; Native Hawaiian; Not Hispanic or Latino; Outcome; Pacific Island Americans; Patient risk; Patients; Peripheral Vascular Diseases; Population; Population Growth; Population Heterogeneity; Prevalence; Primary Prevention; Provider; Psychological Factors; Psychosocial Factor; Public Health; Quality of life; Race; Reporting; Research; Research Design; Risk Factors; Role; Secondary Prevention; Series; Smoking; Socioeconomic Status; Stroke; Subgroup; Surveys; System; Time; United States; cardiovascular disorder prevention; cardiovascular disorder risk; cardiovascular risk factor; comparison group; cost; design; effective intervention; experience; health disparity; high risk; improved; mortality; multidisciplinary; population health; psychosocial; public health relevance; study population; therapy design

 DESCRIPTION (provided by applicant): Cardiovascular disease (CVD) is the leading cause of death in the US, with total costs (including hypertension) of nearly $300 billion in 2008. The progression of CVD occurs over many years and is influenced by a series of demographic, clinical and psychosocial factors that vary across populations. In the US, these factors are least well understood among Asians and Pacific Islanders. Asians are now the fastest-growing minority population in the United States, increasing 43% from 10.2 million to 14.7 million in the past decade.7 Similarly, Native Hawaiian and other Pacific Islander populations have increased by more than 35% during this same time. While Asian populations in the U.S. are commonly thought to be healthier than other minority groups and non-Hispanic Whites, emerging research suggests that some Asian subgroups and Pacific Islanders might be at higher risk for CVD and associated poor outcomes. With such population growth, the health of these populations will have an increasing impact upon future US public health care needs and costs. This compelling CVD knowledge gap about API populations has prompted the American Heart Association and the National Lung, Heart and Blood Institute to call for research that will improve the understanding of CVD among API subpopulations.10 To fill this important gap in knowledge about health disparities among API, we will measure CVD prevalence and outcomes among 9 well-defined API populations, and comprehensively assess the role of demographic, clinical and psychosocial factors in explaining observed differences in CVD prevalence and outcomes among these groups. The multidisciplinary study team brings broad expertise in epidemiology, cardiovascular disease, and the role of social and psychological factors in health disparities. The study population will be drawn from the membership of two large, integrated health care systems located in different geographic regions with large clusters of Asian and Pacific Islander residents (Hawaii and northern California). The study will leverage the rich detail of more than a decade of clinical data contained within electronic health records (EHR) systems of both health plans. We will also collect patient reported data via a large-scale survey of 10,000 people. The study aims are to: 1. Describe differences in the prevalence of CVD among Asian, Pacific Islander, and mixed-race API subpopulations; 2. Determine whether demographic, clinical and psychosocial factors explain observed differences in CVD prevalence among these populations; and 3. Describe differences in CVD outcomes among these populations, including quality of life, and determine whether demographic, clinical and psychosocial factors explain observed differences. Study results will provide important new evidence about underlying factors associated with CVD prevalence and outcomes among rapidly growing, diverse populations in the U.S. This information will provide strategic guidance for targeted interventions at multiple levels-provider, patient, and health system-to reduce CVD mortality and morbidity.

 描述（由适用提供）：心血管疾病（CVD）是美国死亡的主要原因，2008年的总成本（包括高血压）为近3000亿美元。CVD的发展发生了多年，并且受一系列人口统计学，临床和心理社会因素的影响，这些因素遍及整个人群。在美国，这些因素在亚洲人和太平洋岛民中最不了解。现在，亚洲人是美国增长最快的少数民族人口，在过去十年中从1020万增加到1470万。7同样，同一时间，夏威夷人和其他太平洋岛民人口增加了35％以上。尽管通常认为美国的亚洲人口比其他少数群体和非西班牙裔白人更健康，但新兴的研究表明，某些亚洲亚组和太平洋岛民可能面临CVD和相关结果较差的风险。随着人口增长，这些人群的健康将对未来的美国公共保健需求和成本产生越来越多的影响。这一引人入胜的CVD知识差距促使美国心脏协会和国家肺，心脏和血液研究所呼吁进行研究，以提高对API亚群体中CVD的理解。10为了填补这一重要差距，了解API之间的健康差异，我们将在9个良好的CVD流行率和临床中评估API群体中的CVD良好因素和全面的影响，并全面地评估了这些因素，并全面感经性地界定了这些因素，并在全面范围内，并在其中识别CVD的范围，并在了解API之间，并始终如一地评估CVD临床的范围。观察到这些组之间CVD患病率和结果的差异。多学科研究团队为流行病学，心血管疾病以及社会和心理因素在健康分布中的作用带来了广泛的专业知识。该研究人群将从两个大型综合医疗保健系统的成员中得出，该系统位于不同地理区域，其中有大量的亚洲和太平洋岛民居民（夏威夷和北加州）。该研究将利用这两个健康计划中的电子健康记录（EHR）系统中包含的十多年的临床数据的丰富细节。我们还将通过对10,000人进行的大规模调查收集患者报告的数据。该研究的目的是：1。描述亚洲，太平洋岛民和混合种族API亚群中CVD患病率的差异； 2.确定人口，临床和社会心理因素是否解释了这些人群中CVD患病率的差异；和3。描述这些人群中CVD结局的差异，包括生活质量，并确定人口，临床和社会心理因素是否解释了观察到的差异。研究结果将提供有关与CVD患病率相关的潜在因素以及美国迅速增长，潜水员种群中的基本因素的重要新证据，该信息将为在多个级别提供者，患者和卫生系统的有针对性干预措施中提供战略指导，以降低CVD死亡率和发病率。