Training in Reproductive Sciences

生殖科学培训

• 批准号: 9385648
• 负责人: PAMELA L MELLON
• 金额: $ 0.68万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-12-01 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9385648
• 关键词: Science; Training; reproductive

DESCRIPTION (provided by applicant): The urgency and importance of producing critically needed basic, translational, and clinical scientists in the area of women's health and reproduction is well recognized by the leadership of NIH, the scientific community, the national government, and the society as a whole. The UCSD T32 Training Program in Reproductive Sciences takes a unique multidisciplinary approach to the training of postdoctoral scholars as physician- scientists and reproductive biologists in the field of neuroendocrine and endocrine control of reproductive processes. The combination of clinical, physiological, and molecular approaches to reproductive biology and medicine creates an exceptional opportunity for the training of physician-scientists and basic scientists, as well- rounded reproductive endocrinologists who become extraordinarily qualified for academic careers. The program supports both fellows seeking advanced basic/translational research experience after the Ph.D. and/or M.D. degree, and those seeking clinical and research training with the aim of becoming board-certified in Reproductive Endocrinology and Infertility and continuing in academic clinical research. We have an outstanding 30-year track record as recognized by an NIH MENTOR AWARD that extended the program for 10 years from 2003-2012. A cohesive group of NIH-funded faculty from the Division of Reproductive Endocrinology in the Department of Reproductive Medicine and the Division of Endocrinology in the Department of Medicine at UCSD with common interests, shared grants, joint publications, and complimentary backgrounds, provides basic, translational, and clinical training and fosters the success and careers of the trainees. All faculty are members of the UCSD NICHD U54 Specialized Cooperative Centers Program in Reproductive and Infertility Research and all of the senior faculty members are mentors in the UCSD NICHD K12 Women's Reproductive Health Research Program for the training of OB/GYN junior faculty in research careers. Thus, this training program is integrated with both NICHD Centers, allowing the faculty and fellows to interact at many levels, creating an atmosphere of cooperation, collaboration, mentoring, and career support. Our research activities range from molecular to patient-oriented research utilizing models from in vitro analysis and cell culture, to whole animal and clinical research. Major foci of investigation include: gonadal, pituitary and hypothalamic development, ovarian physiology, polycystic ovary disease, signal transduction, Kisspeptin, NeurokininB, GnRH, and gonadotropin gene expression and secretion, metabolic impact on reproductive function, and activin and growth factors in reproduction. The program of training for the fellows includes group meetings and presentations, journal clubs, seminars, national meetings, clinical activity and training, laboratory training, independent research, grantsmanship training, and coursework in molecular biology, neuroendocrinology, bio- statistics, and ethics, and an innovative "Thesis Committee" mentoring structure. Our aim is to prepare outstanding physician-scientists and basic scientists to become the future leaders in academic reproductive research.

描述（由申请人提供）：在妇女健康和生殖领域培养急需的基础，转化和临床科学家的紧迫性和重要性得到了NIH，科学界，国家政府和整个社会的领导层的认可。UCSD T32生殖科学培训计划采用独特的多学科方法来培训博士后学者作为生殖过程神经内分泌和内分泌控制领域的医生-科学家和生殖生物学家。生殖生物学和医学的临床，生理和分子方法的结合为医生科学家和基础科学家的培训创造了一个特殊的机会，以及全面的生殖内分泌学家，他们成为非常合格的学术职业。该计划支持两位研究员在博士学位后寻求高级基础/翻译研究经验。和/或医学博士学位，以及那些寻求临床和研究培训的人，目的是成为生殖内分泌学和不孕症的委员会认证，并继续进行学术临床研究。我们有一个杰出的30年的跟踪记录，由美国国立卫生研究院导师奖，从2003年至2012年延长了10年的计划承认。一个由NIH资助的教师组成的有凝聚力的小组，来自生殖医学系生殖内分泌科和UCSD医学系内分泌科，具有共同的兴趣，共同的赠款，联合出版物和免费的背景，提供基础，翻译和临床培训，并促进学员的成功和职业生涯。所有教师都是UCSD NICHD U 54生殖和不孕不育研究专业合作中心计划的成员，所有高级教师都是UCSD NICHD K12妇女生殖健康研究计划的导师，用于研究职业中OB/GYN初级教师的培训。因此，该培训计划与两个NICHD中心相结合，允许教师和研究员在多个层面进行互动，创造合作，协作，指导和职业支持的氛围。我们的研究活动范围从分子到以患者为导向的研究，利用体外分析和细胞培养模型，整个动物和临床研究。主要研究领域包括：性腺、垂体和下丘脑发育、卵巢生理学、多囊卵巢疾病、信号转导、Kisspeptin、神经激肽B、GnRH和促性腺激素基因表达和分泌、代谢对生殖功能的影响以及生殖中的激活素和生长因子。研究员的培训计划包括小组会议和演讲、期刊俱乐部、研讨会、全国会议、临床活动和培训、实验室培训、独立研究、granimetry培训、分子生物学、神经内分泌学、生物统计学和伦理学课程以及创新的“论文委员会”指导结构。我们的目标是准备优秀的医生，科学家和基础科学家成为学术生殖研究的未来领导者。