International Health Research Ethics Training Program

描述（申请人提供）：撒哈拉以南非洲仅占世界人口的11%，但却占全球疾病负担的24%以上，占世界艾滋病毒感染者的70%以上，仅占全球劳动力的3%，用于卫生的财政资源不到世界的1%。在乌干达这个有3 500万人口、疾病负担沉重的国家，只有7名乌干达专家受过生物伦理学硕士培训。这7人是一个由9名生物伦理学家组成的小组的一部分，他们都在北美和欧洲接受过培训，其中2人在接受生物伦理学培训后离开了该国，去了更好的地方。有必要在乌干达开始培训，以弥补供应缺口。在该地区内进行培训将降低该计划的成本，因为接受培训的人数增加，并提高保留率。该项目是创新的，并提出了一个可持续的并行三级国际道德培训计划，包括证书， 文凭和硕士学位的奖励，建立一个坚实的基础，随后的博士培训（不属于本建议的一部分）在大约十年的时间。该国际研究伦理计划的总体目标是产生可持续供应的毕业生，他们将表现出领导力，并为提高研究伦理的标准和实践做出重大贡献，以保护乌干达和更广泛的撒哈拉以南非洲地区研究参与者的安全和福利。这将通过培养：（1）毕业生能够在国际研究伦理方面发挥领导作用，并有效地应用于教学和指导个人参与健康研究，管理研究项目/计划，并提供生物伦理服务咨询和政策建议。(2)能够对具有挑战性的伦理问题进行经验和应用研究的个人。能够有效提供国际研究伦理咨询服务和政策建议的从业人员和研究人员。这将通过各种与道德有关的课程来实现，这些课程的提供以成人学习的使用原则和方案的其他特点为指导，旨在确保受训者获得的知识转移到他们的家庭机构环境中。预计这将有助于加强乌干达和该地区研究伦理能力的提高，以保持高质量的国际研究伦理。与公共服务部和卫生部等相关政府部门合作，我们将确保该计划毕业生的职业道路在乌干达得到明确界定，从而成为其他非洲国家的榜样。拥有91年历史的马凯雷雷大学拥有近40，000名学生，是迄今为止乌干达最古老和最大的大学，也是撒哈拉以南非洲研究最密集的大学之一，在非洲大陆排名前10位。健康科学学院有医学、公共卫生、生物医学科学和健康科学四个大的学院，包括护理、药学和牙科系。该大学拥有一个庞大而迅速扩大的健康研究企业，由于学院有许多国际研究合作。东非区域国家集团（肯尼亚、卢旺达、坦桑尼亚、乌干达和布隆迪）为开创性的研究做出了贡献，这些研究在国际上影响了政策和做法的变化，特别是在传染病方面，包括被忽视的热带病，但也越来越多地影响到非传染病、卫生系统和其他卫生挑战。马凯雷雷大学的愿景是成为一所研究型大学，并成为公认的区域和参考中心，为伦理挑战提供咨询，研究优先挑战的国际伦理学，并发展生物伦理学研究能力。

DESCRIPTION (provided by applicant): Sub Saharan Africa with only 11% of the world's population has more than 24% of the global disease burden, over 70% of the world's HIV infected persons, and only 3% of the global work force, and spends less than 1% of the world financial resources on health. In the case of Uganda, a country of 35 million people who suffer with a heavy disease burden, there are only 7 Ugandan specialists trained at masters level in bioethics. These 7 are part of a group of 9 bioethicists who were all trained in North America and Europe of whom 2 have since left the country for greener pastures after their bioethics training. There is need to start training in Uganda in order to bridge the supply gap. Training within the region will reduce the cost of the program as a result of the increased numbers of individual trained and result in higher retention rates. The project is innovative and proposes a sustainable concurrent three level international ethics training program that includes certificate, diploma and master's degree awards that build a strong foundation for subsequent doctoral training (not part of this proposal) in about ten years' time. The overarching goal of this international research ethics program is to produce a sustainable supply of graduates who will show leadership and significantly contribute to improving standards and practice of research ethics to protect the safety and welfare of research participants in Uganda and the wider sub-Saharan Africa region. This will be done by developing: (1) Graduates capable of providing leadership in international research ethics and apply it effectively in teaching and mentoring individuals to participate in health research, manage research projects/ programs and also offer bioethics services consultations and policy advice. (2) Individuals who can undertake empirical and applied research on challenging ethical issues. And (3) Practitioners and researchers who can effectively provide consultation services and policy advise in international research ethics. This will be done using various ethics related courses whose delivery is guided by the use principles of adult learning and other features of the program aimed at ensuring the transfer of knowledge gained by the trainee to their home institutional environment. This is expected to contribute to strengthening improvements in research ethics capacity in Uganda and in the region to sustain high quality of international research ethics. Working with the relevant government departments like ministries of Public Service and of Health we will ensure that a career path for graduates of the program is well defined in Uganda and this may thus become a role model for other African countries. The 91 year old Makerere University with a student population of nearly 40,000 is by far the oldest and largest university in Uganda and is one of the most research intensive universities in Sub-Saharan Africa, ranked among the top 10 universities on the continent. The College of Health Sciences has four large schools of Medicine, Public Health, Biomedical Sciences and Health Sciences that include the Departments of Nursing, Pharmacy and Dentistry. The university has a large and rapidly expanding health research enterprise due to the many international research collaborations the college has. The East African regional block of countries (Kenya, Rwanda, Tanzania, Uganda and Burundi) have contributed to ground breaking research that has impacted policy and practice changes internationally particularly on communicable diseases including neglected tropical diseases, but also increasingly on non-communicable diseases, health systems and other health challenges. The Makerere University's vision is to become a research driven university and serve as a recognized regional and reference center of first choice for advice on ethical challenges, research on international ethics regarding priority challenges and for development of bioethics research capacity.