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Use of Novel Mobile Technology to Screen Sexual Partners for HIV and STIs

使用新型移动技术筛查性伴侣的艾滋病毒和性传播感染

基本信息

批准号：
9270044
负责人：
Ivan C Balan
金额：
$ 58.05万
依托单位：
NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-05-05 至 2020-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9270044
关键词：
Acquired Immunodeficiency Syndrome Antibodies Anus Balan Behavior Behavioral Biomedical Engineering Blood Blood Tests Caring Cellular Phone Computers Conscious Detection Development Devices Drops Early treatment Electronics Empathy Engineering Epidemic Feedback Frequencies Funding HIV HIV Infections HIV Seropositivity HIV/STD Hand Harm Reduction Health High Risk Woman Home environment Human immunodeficiency virus test Incidence Individual Infection Instruction Intervention Interview Interviewer LIF gene Lead Link Methods Monitor Motivation Newly Diagnosed Participant Phase Phonation Prevention Prevention strategy Recommendation Research Research Personnel Risk Risk Assessment Schools Sex Behavior Sexual Partners Shapes Symptoms Syphilis Technology Telephone Test Result Testing Time Universities Use Effectiveness Visit Work base condoms experience high risk high risk population high risk sexual behavior innovation men men who have sex with men mobile computing monitoring device novel novel strategies pre-exposure prophylaxis prevent public health relevance screening seroconversion sex risk sexual encounter skills social norm tool transgender women transmission process usability

项目摘要

DESCRIPTION (provided by applicant): Increasing incidence of HIV and STIs among men who have sex with men (MSM) and transgender women (TGW) highlight the need for novel approaches to reducing infections-especially among individuals who do not use condoms consistently. Our prior studies on the use of rapid HIV self-testing (ST) by MSM who regularly engage in high-risk sexual behavior, show that these men are willing to use ST with partners, avoid intercourse in situations where partners test HIV-positive, and, over time tend to reduce their high-risk sexual behavior. This proposed study expands this line of research by exploring the use of a new device, the mChip dongle. Developed at the Columbia University School of Engineering, this device uses smartphone technology to analyze a drop of blood and test it for HIV and syphilis antibodies. The mChip dongle brings more precision to ST, tests for HIV and syphilis and potentially other STIs, and can capitalize on smartphone technology to provide clearer user instructions, on-hand information about HIV/STI, remote monitoring of the its use, and linkage of newly diagnosed individuals to care. For this proposed quantitative and qualitative study, we will again focus on HIV-uninfected MSM and TGW with multiple sexual partners who know how to prevent HIV infection, yet engage in high-risk sexual behavior. The Specific Aims are to: 1) Assess acceptability among MSM and TGW of using the mChip dongle to test sexual partners; 2) Optimize the smartphone app and mChip dongle for home use; and 3) Assess the feasibility of using the mChip dongle to test sexual partners, including: a) frequency of use of the mChip dongle with sexual partners over 3 months; b) factors associated with mChip dongle use or non-use; c) condom use with partners who were not screened vs. partners screened HIV or STI- negative with the mChip dongle; and d) factors associated with changes in sexual risk behavior over 3 months. The study consists of two phases. In Phase 1A, 60 participants will undergo a quantitative, qualitative, and skill-demonstration assessment (using the mChip dongle in front of the interviewer) in a single study visit. Phase 1A findings wil inform Phase 1B, which focuses on revising the smartphone app and mChip dongle for home users, as well as revisions to the Phase 2 assessment. In Phase 2A, 80 new participants will undergo a baseline quantitative and skill-demonstration assessment in order to screen for 50 participants who will be invited into the Phase 2B 3-month study. These 50 participants will be provided with an mChip dongle and given the choice to use it to screen sexual partners. After 3 months participants will undergo a quantitative and qualitative interview about experiences using (or not using) the mChip dongle with partners. This study will capitalize on a critical juncture in the development of the mChip dongle by systematically engaging its intended users in offering feedback to the engineering team on how to optimize its usability and acceptability among high-risk populations. This study will also allow us to assess the feasibility of conducting a larger and longer trial to develop and test an mChip-based harm-reduction intervention.