Patterns and Risk Factors of HIV and Non-Communicable Disease Co-Morbidity in Urban Tanzania-Exploring the Potential for Family-Based Interventions

坦桑尼亚城市艾滋病毒和非传染性疾病共病的模式和危险因素——探索基于家庭的干预措施的潜力

• 批准号: 9231666
• 负责人: Virginia Fonner
• 金额: $ 17.14万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9231666
• 关键词: Address; Adult; Africa; Africa South of the Sahara; Anti-Retroviral Agents; Area; Attitude; Behavioral; Belief; Blood Pressure; Body Weight decreased; Caring; Chronic; Chronic Care; Chronic Disease; Client; Clinic Visits; Collaborations; Communicable Diseases; Comorbidity; Country; Development; Diabetes Mellitus; Diagnosis; Diet; Disease; Disease Outcome; Disease Progression; Economics; Environment; Etiology; Face; Family; Family member; Foundations; Funding; Future; Glycosylated hemoglobin A; Goals; HIV; Health; Health system; Home environment; Hypertension; Income; Institution; Intervention; Interview; Knowledge; Lead; Life; Life Style; Link; Long-Term Care; Maintenance; Medical; Metabolic syndrome; Methods; Non-Insulin-Dependent Diabetes Mellitus; Outcome; Patients; Pattern; Pharmaceutical Preparations; Physical activity; Positioning Attribute; Prevalence; Public Health; Research; Research Infrastructure; Research Personnel; Resources; Risk; Risk Factors; Role; Rural; Sampling; Scientist; Self Care; Self Efficacy; Services; Site; Social status; Social support; System; Tanzania; Testing; Time; Treatment Efficacy; base; cost effective; design; diet and exercise; disorder risk; efficacy trial; experience; family support; healthy lifestyle; improved; innovation; low income country; medication compliance; multidisciplinary; population health; screening; success

PROJECT SUMMARY/ABSTRACT Non-communicable diseases (NCDs), including diabetes and hypertension, are becoming grave emerging health threats in sub-Saharan Africa, especially among people living with HIV. The health of people living with NCDs and HIV could be significantly improved through interventions encouraging behavioral lifestyle changes, and family-based interventions to enact such change show exciting promise. However, little research has been conducted on these conditions and on interventions to address them in sub-Saharan Africa. In contrast, HIV has been extensively researched and has become a chronic condition in these settings. Due to the existing, well-developed infrastructure of HIV-related services and the commonalities in providing long-term care for HIV and NCDs, developing interventions that integrate screening and care for non-communicable diseases with HIV care is needed. However, more needs to be understood on the prevalence and risk factors of these conditions prior to developing an effective, feasible intervention. Therefore, this mixed methods study seeks to (1) establish the prevalence and risk factors of diabetes and hypertension among people receiving HIV-related care in urban Tanzania and (2) understand families’ knowledge, beliefs, and actions relating to diabetes and hypertension and how this can lead to implementing a family-centered intervention to improve health for this population. To realize these objectives, we propose screening 364 clients receiving HIV-related care for diabetes and hypertension and conducting further assessments with a sub-set of clients’ families. Within 40 families, we will conduct home-based screening for diabetes and hypertension for all adult family members. These families will also be interviewed to assess their understanding of diabetes and hypertension, how the family environment contributes to NCD risks, and how the family can be used to increase support and decrease NCD risks for people living with HIV. Results from this study will be used to develop and test a relevant, culturally-appropriate family-based intervention to improve patient health outcomes for HIV and NCDs.

项目总结/摘要 包括糖尿病和高血压在内的非传染性疾病正在变得越来越严重， 在撒哈拉以南非洲，特别是艾滋病毒感染者的健康威胁。与艾滋病患者一起生活的人的健康 通过鼓励改变行为生活方式的干预措施，非传染性疾病和艾滋病毒可以得到显著改善， 而以家庭为基础的干预措施也显示出令人振奋的前景。然而，很少有研究 在撒哈拉以南非洲，针对这些条件和干预措施进行了研究。相比之下，艾滋病毒 已被广泛研究，并已成为一种慢性疾病，在这些设置。由于现有的、 与艾滋病毒有关的服务的完善基础设施和提供艾滋病毒长期护理的共同点 和非传染性疾病，制定干预措施，将非传染性疾病的筛查和护理 艾滋病需要护理。然而，需要更多地了解这些疾病的患病率和风险因素， 在制定有效、可行的干预措施之前，因此，这项混合方法研究旨在 (1)确定接受艾滋病毒相关治疗的人中糖尿病和高血压的患病率和危险因素， （2）了解家庭对糖尿病的知识、信念和行动， 高血压，以及这如何导致实施以家庭为中心的干预措施，以改善健康， 人口为了实现这些目标，我们建议对364名接受艾滋病毒相关护理的病人进行筛查， 糖尿病和高血压，并与一组客户家庭进行进一步评估。只需40 在家庭方面，我们会为所有成年家庭成员进行糖尿病和高血压的家居检查。 这些家庭也将接受采访，以评估他们对糖尿病和高血压的理解， 家庭环境有助于非传染性疾病的风险，以及如何利用家庭来增加支持， 降低艾滋病毒感染者的非传染性疾病风险。这项研究的结果将用于开发和测试一种 相关的、文化上适当的、以家庭为基础的干预措施，以改善艾滋病毒患者的健康结果， 非传染性疾病