2018 Proteoglycans Gordon Research Conference and Gordon Research Seminar

项目摘要/摘要 戈登蛋白质多糖研究会议(GRC)是一次订阅量很高的会议， 来自领域领导者的口径未公布的数据，并提供了促进合作的非常合群的氛围。 大会自1984年起每两年举办一次，口碑卓著。此当前应用程序 正在请求为下一次会议提供部分支持，会议名为“稳态和疾病中的蛋白质多聚糖：破解 PG Code“，将于2018年7月8日至13日在密歇根州安多弗的普罗科特学院举行。计划中的会议 节目由一个科学组织委员会选出的特邀演讲者组成，该委员会包括前 Proteoglycan GRC主席，其他研究人员提供意见，他们在这一广泛的领域拥有丰富的专业知识 研究领域。除了聚集了成就卓著的著名蛋白多糖研究科学家外， 其中一些人以前没有参加过这次GRC，会议为早期阶段提供了一个论坛 调查人员在海报会议和简短演讲中展示他们的工作，后者被选为 作为会议主题的补充。我们的目标是，该计划将涵盖前沿的最新研究 并为我们社区内的职业发展提供机会。 延长的讨论时间、小组聚餐和社交活动为与会者提供了充分的机会讨论 在他们的蛋白多糖领域的分支中，学习新的研究工具，并建立 新的合作..在2018年的会议上，将会报道蛋白多糖在 骨、肌肉、肌腱和椎间盘的发育、动态平衡和病理学。其他高的话题 将包括与肌肉骨骼研究的相关性，如衰老、自噬、细胞信号、纤维化、 炎症、新陈代谢和氧化应激。这些领域也将在癌症的背景下讨论， 心血管疾病、宿主-病原体相互作用、溶酶体储存障碍和神经生物学。这个 会议还将展示新开发的用于蛋白多糖研究的工具和技术，以及 蛋白多糖作为治疗学和组织工程方法的发展。 Proteoglycan GRC努力做到包容，通常实现了男性和女性的近乎平等的平衡 代表们展示了来自世界各地的科学家..与会者将通过邀请或从以下方式选择 这些申请是在网上提交的，将被选为包括一组不同的研究人员。附加输入 2018年，我们将增加一个讨论科学生涯中存在的性别问题/障碍的力量小时 发展。

Project Summary / Abstract The Gordon Research Conference (GRC) on Proteoglycans is a well-subscribed meeting that presents high caliber unpublished data from field leaders and provides a very collegial atmosphere that fosters collaboration. The conference has been held biennially since 1984 and has an outstanding reputation. This current application is requesting partial support for the next conference, “Proteoglycans in Homeostasis and Disease: Cracking the PG Code”, which will be held during July 8-13, 2018 at Proctor Academy, Andover, NH. The planned conference program is composed of invited speakers chosen by a scientific organizing committee that includes former Proteoglycan GRC Chairs with input from other investigators who have substantial expertise across this broad research area. In addition to bringing together highly accomplished, renowned proteoglycan research scientists, some of whom will have not attended this GRC previously, the conference provides a forum for early stage investigators to present their work in poster sessions and short talks, where the latter are selected to be complementary to the session themes. Our aim is that the program will cover the latest research at the forefront of the proteoglycan field and provide opportunities for career development within our community. The extended discussion times, group meals and social events give attendees ample opportunity to discuss the specific ‘state of the art’ within their branch of the proteoglycan field, learn of novel research tools, and establish new collaborations.. At the 2018 conference, there will be coverage of the role of proteoglycans in the development, homeostasis and pathology of bone, muscle, tendon and intervertebral disc. Other topics of high relevance to musculoskeletal research will be included, such as aging, autophagy, cell signaling, fibrosis, inflammation, metabolism and oxidative stress. These areas will also be discussed in the contexts of cancer, cardiovascular disease, host-pathogen interactions, lysosomal storage disorders and neuronal biology. The conference will additionally feature newly developed tools and technologies for proteoglycan research, and the development of proteoglycans as therapeutics and in tissue engineering approaches. The Proteoglycan GRC strives to be inclusive, typically achieving a near equal balance of male and female delegates and showcasing scientists from throughout the world.. Attendees will be selected by invitation or from the applications submitted online and will be chosen to comprise a diverse set of researchers, . Additionally in 2018 we will add a Power Hour for discussion of gender issues/ impediments that exist in scientific career development.