Analytical Biochemistry

分析生物化学

• 批准号: 9634852
• 负责人: Douglas Yee
• 金额: --
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-02-01 至 2019-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9634852
• 关键词: 1,3-Butadiene; 2-butenal; Acetylcysteine; Acrolein; Analytical Biochemistry; Analytical Chemistry; Aromatic Polycyclic Hydrocarbons; Benzene; Biological; Biological Markers; Butanones; Cancer Center; Cancer Center Support Grant; Carcinogens; Cardiovascular system; Chemoprevention; Chromatography; Consult; Contract Services; Coupled; DNA Adducts; Doctor of Philosophy; Equipment; Ethylene Oxide; Etiology; Funding; Gas Chromatography; Glucuronides; Head; High Pressure Liquid Chromatography; Human Resources; Liquid Chromatography; Maintenance; Malignant Neoplasms; Mass Spectrum Analysis; Mission; N' -nitrosonornicotine; Nature; Nicotine; Nitrosamines; Nucleic Acids; Nucleosides; Oligonucleotides; Organic Chemistry; Peptides; Plasma; Prevention; Proteins; Proteomics; Research; Research Activity; Research Personnel; Resource Sharing; Resources; Scientist; Services; Site; Techniques; Time; Tobacco; Tobacco-Associated Carcinogen; Universities; Urine; carcinogenesis; cost; cost effective; cost efficient; design; experience; instrument; instrumentation; mass spectrometer; member; method development; operation; programs; repaired; small molecule; tobacco toxicant; toxicant; urinary

The mission of the Analytical Biochemistry Shared Resource is to provide high-quality analytical services to members of the Masonic Cancer Center (MCC) by providing state-of-the-art chromatographic, mass spectrometric, and related techniques, in a timely and cost-efficient manner. The Resource provides • mass spectrometry services • analytical biochemistry services, emphasizing tobacco carcinogen and toxicant biomarker analyses • chromatography services: on-site consulting for the maintenance and service of high-performance liquid chromatography and gas chromatography equipment Stephen Hecht, PhD, the director of Analytical Biochemistry, has many years of experience in analytical organic chemistry and mass spectrometry. Four other staff members also bring decades of experience with mass spectrometry (Dr. Peter Villalta and Brock Matter), nicotine metabolites (Dr. Sharon Murphy), and chromatography (Steven Carmelia). Analytical Biochemistry remains an outstanding and extensively used resource that serves members of almost all of the MCC Programs as well as other researchers at the University. The specialized nature of the facility enables services to be provided at very cost-effective rates, while providing users access to equipment in a timely manner. Most instruments are maintained and repaired by Resource staff, avoiding the need for costly service contracts. Members of the MCC rely on Analytical Biochemistry staff for guidance on related projects, method development, and troubleshooting of instruments. This heavily used and technically outstanding facility continues to provide crucial services to its highly productive users.

分析生物化学共享资源的使命是提供高质量的分析服务