The Health ePeople Resource for Mobilized Research

管理核心-项目概要/摘要 我们寻求创建健康ePeople资源，这是一个灵活，易于访问和可靠的基础设施， 进行mHealth研究。这项工作将建立在目前的健康电子心脏研究，一个基于互联网的临床 该研究平台已招募了来自世界各地的20，000多名参与者。虽然 最初是为了研究心血管疾病而开发的，健康eHeart被来自多个领域的研究人员使用， 并帮助我们启动当前RFA中设定的许多目标。我们成功地实施了一项 用户友好的界面，用于收集患者报告的结局、经验证的调查数据，并与 多个传感器、设备和应用程序;我们有一个IRB批准的系统，使用模块化电子同意; 我们有超过20，000名有兴趣为移动健康研究做出贡献的参与者;我们有 为外部研究者开发了以可定制的方式利用和招募他们自己的参与者的方法; 我们开发了一个研究管理门户（包括实时仪表板和参与者特征- 基于过滤系统）和一个灵活的消息传递系统，可供外部调查人员使用;我们有 建立了一个数据库和数据管理系统，以遵守最高的隐私标准， 安全性和可靠性;我们已经迭代和调整了平台，以利用新兴的 技术和尖端方法。在这些优势的基础上，我们准备充分利用 该奖项提供的机会，将健康eHeart研究转变为一般健康ePeople Resource.行政核心将由管理卫生保健的人员基础设施组成， ePeople资源，并将为来自学术界、非营利组织和非政府组织的调查人员提供行政支持。 组织，政府机构和行业使用健康ePeople资源进行研究。 行政核心将提供行政基础设施，以确保数据安全和隐私， 与各种合作者，mHealth产品和研究设计合作。行政核心将 负责开发和管理健康电子人的可持续财务模式 Resource.最后，行政核心将提供管理公共事务的行政基础设施。 关系、营销、通信和知识传播。

ADMINISTRATIVE CORE— PROJECT SUMMARY/ABSTRACT We seek to create the Health ePeople Resource, a nimble, readily-accessible, and reliable infrastructure to conduct mHealth research. This effort will build on the current Health eHeart Study, an internet-based clinical research platform that has enrolled more than 20,000 engaged participants from around the world. Although initially developed to study cardiovascular disease, Health eHeart is in use by investigators from multiple fields, and helps us jumpstart many of the objectives set out in the current RFA. We have successfully implemented a user-friendly interface built to collect patient-reported outcomes, validated survey data, and integrations with multiple sensors, devices, and apps; we have an IRB approved system using modular electronic consenting; we have over 20,000 deeply involved participants interested in contributing to mHealth research; we have developed ways for external investigators to utilize and enroll their own participants in a customizable fashion; we have developed a study management portal (including a real-time dashboard and participant characteristic- based filtering system) and a flexible messaging system that can be utilized by external investigators; we have built a database and data management system constructed to adhere to the highest standards of privacy, security, and reliability; and we have iterated and adapted the platform to take advantage of emerging technology and cutting-edge methods. Building from these strengths, we are ready to fully leverage the opportunities afforded by this award, transforming the Health eHeart Study into a general Health ePeople Resource. The Administrative Core will be comprised of the personnel infrastructure to manage the Health ePeople Resource and will provide the administrative support for investigators from academia, nonprofit organizations, governmental agencies and industry to conduct research using the Health ePeople Resource. The Administrative Core will provide the administrative infrastructure to ensure data security and privacy in working with a variety of collaborators, mHealth products, and research designs. The Administrative Core will be responsible for the development and management of a sustainable financial model for the Health ePeople Resource. Finally, the Administrative Core will furnish the administrative infrastructure to manage public relations, marketing, communications and dissemination of knowledge.