Magnesium sulphate in women at risk of preterm birth for fetal neuroprotection - an individual patient data review

硫酸镁对有早产风险的女性的胎儿神经保护作用 - 个体患者数据审查

• 批准号: nhmrc : 627228
• 负责人: A/Pr Lisa Askie
• 金额: $ 18.4万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/magnesium-sulphate-women-patient-review/82702
• 关键词: Magnesium; sulphate; women; risk; preterm

Infants born preterm are at high risk of dying and survivors have a higher risk of neurological problems. Evidence suggests that giving magnesium sulphate to women at risk of preterm birth prior to delivery reduces cerebral palsy in surviving children. It is unclear which women may benefit, what dose and when prior to birth should magnesium sulphate be given. This review will determine how individual women should be treated with magnesium to help protect the brain of a baby born too soon.

早产婴儿死亡的风险很高，幸存者患神经系统疾病的风险更高。有证据表明，在分娩前给有早产风险的妇女服用硫酸镁可减少幸存儿童脑瘫的发生。目前尚不清楚哪些妇女可能受益，在出生前应给予多大剂量以及何时给予硫酸镁。这项研究将决定个体女性应该如何接受镁的治疗，以帮助保护早产婴儿的大脑。