Breast Oncology Program
Breast Oncology Program
批准号:
9784179
负责人:
Laura J Van't Veer
金额:
$1.07万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AgeBiologicalBiologyBreast Cancer Risk FactorBreast OncologyCDC2 Protein KinaseCDK2 geneCancer Center Support GrantCancer EtiologyCaringCessation of lifeClinical TrialsDevelopmentDiagnosticDirect CostsDiseaseERBB2 geneERBB3 geneEpithelial-Stromal CommunicationFundingGoalsHarm ReductionHealthcareHeterogeneityHomeostasisImageIndividualInterventionKnowledgeMalignant - descriptorMalignant NeoplasmsMammographic DensityMammographyMetabolismMissionMolecularOutcomePIM1 genePathway interactionsPatientsPeer ReviewPhysiologicalPredispositionProcessPublicationsRadiation exposureResearch PersonnelRisk EstimateSan FranciscoSchoolsScienceTherapeuticTissuesToxic effectWomanWorkbasecheckpoint modulationcostdisorder riskdrug developmenthigh riskimmune checkpointimprovedimproved outcomeindividualized medicineinnovationmalignant breast neoplasmmammography registrynew therapeutic targetoncology programovertreatmentpersonalized diagnosticspersonalized screeningpreventprogramsrandomized trialresponseroutine screeningscreeningsuccesstooltrial designtriple-negative invasive breast carcinoma
中文摘要
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英文摘要
Breast Oncology Program: Summary
The mission of the Breast Oncology (BR) Program is to develop innovative approaches to describe the
molecular and cellular networks underlying breast cancer susceptibility, heterogeneity, diversity, and disparities
with the aim of improving outcomes for healthy women and women with breast cancer. The BR Program's
work aims to reduce overdiagnosis and overtreatment through individualizing screening and treatment, and
derive better outcomes at lower cost. The BR Program achieves its goals through four themes:
Theme 1: Improving the Understanding of Breast Cancer Etiology in the Context of the Microenvironment
Theme 2: Personalizing Screening and Diagnostics to Increase Health Care Value
Theme 3: Identifying New Therapeutic Targets for High-risk Disease
Theme 4: Augmenting Efficiency of Drug Development through Innovative Trial Design
BR Program: Key Metrics
Membership (14 departments, 3 schools) 33
Full 18
Associate 15
Cancer-relevant Funding (direct costs as of
$14,454,243
05/31/2017)
NCI $5,307,970 37%
Peer-reviewed $4,630,302 32%
Non-peer-reviewed $4,515,971 31%
Cancer-relevant Publications (1/2012-7/2017) 636
Inter-programmatic 141 22%
Intra-Programmatic 175 28%
High-Impact 190 30%
Accruals to Clinical Trials (2016) 5293 58
Therapeutic 140 31
Other Interventional 9 4
Non-interventional 5144 22
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Project 3: Characterization of the biology of non-responders using Imaging and molecular analysis to inform treatment
-
批准号:10628611
-
项目类别:
-
资助金额:$86.58万
-
财政年份:2017
-
负责人:Laura J Van't Veer
-
依托单位:
Project 03 - Understanding the biology of non-responders to inform treatment selection
-
批准号:10249156
-
项目类别:
-
资助金额:$15.94万
-
财政年份:2017
-
负责人:Laura J Van't Veer
-
依托单位:
Project 03 - Understanding the biology of non-responders to inform treatment selection
-
批准号:10013139
-
项目类别:
-
资助金额:$22.87万
-
财政年份:2017
-
负责人:Laura J Van't Veer
-
依托单位:
Breast Oncology Program
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批准号:10406945
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项目类别:
-
资助金额:$8.73万
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财政年份:1999
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负责人:Laura J Van't Veer
-
依托单位:
Breast Oncology Program
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批准号:10712665
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项目类别:
-
资助金额:$18.33万
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财政年份:1999
-
负责人:Laura J Van't Veer
-
依托单位:
SPORE in Breast Cancer
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批准号:8250847
-
项目类别:
-
资助金额:$230.0万
-
财政年份:1997
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负责人:Laura J Van't Veer
-
依托单位:
SPORE in Breast Cancer
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批准号:8039212
-
项目类别:
-
资助金额:$190.23万
-
财政年份:1997
-
负责人:Laura J Van't Veer
-
依托单位:
Project 03 - Understanding the biology of non-responders to inform treatment selection
-
批准号:9560699
-
项目类别:
-
资助金额:$29.68万
-
财政年份:--
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负责人:Laura J Van't Veer
-
依托单位:
Project 03 - Understanding the biology of non-responders to inform treatment selection
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批准号:9789201
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项目类别:
-
资助金额:$28.1万
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财政年份:--
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负责人:Laura J Van't Veer
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依托单位:
海外基金