The Role of Emotion in Word Production in Adults With and Without Aphasia

情绪在患有和不患有失语症的成年人的言语产生中的作用

• 批准号: 9759715
• 负责人: Deena Schwen Blackett
• 金额: $ 3.81万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-01 至 2021-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9759715
• 关键词: Acquired Language Disorders; Address; Adult; Age; Aging; Anomia; Aphasia; Arousal; Attention; Behavioral; Brain Injuries; Categories; Characteristics; Clinical; Communication impairment; Data; Development; Diagnostic; Educational workshop; Elderly; Emotional; Emotions; Fellowship; Frequencies; Generations; Goals; Grant; Image; Individual; Investigation; Knowledge; Language; Language Disorders; Lead; Linguistics; Literature; Measures; Mentorship; Modeling; Motivation; Names; Neurologic; Participant; Performance; Play; Population; Prevalence; Process; Production; Reaction Time; Reading; Research; Research Design; Research Training; Retrieval; Role; Series; Short-Term Memory; Statistical Data Interpretation; Stimulus; Symptoms; Testing; Theoretical model; Thinking; Training; Universities; Writing; age related; auditory comprehension; clinical material; clinical practice; clinically significant; comparison group; design; emotional factor; emotional stimulus; experience; experimental study; healthy aging; improved; language impairment; language processing; normal aging; post stroke; preference; recruit; skills; stroke survivor; success; theories; therapy design; young adult

PROJECT SUMMARY/ABSTRACT Aphasia is a communication disorder that can occur after stroke and impacts approximately one-third of stroke survivors. One of the hallmark symptoms of aphasia is anomia or difficulty thinking of the word one wants to use (i.e., word retrieval). Due to the prevalence of anomia across people with aphasia (PWA), many assessment and treatment approaches have focused on this symptom. Choosing appropriate stimuli is important to diagnostic and treatment success. Characteristics of pictured or written stimuli (e.g. word frequency or imageability) impact the ease with which one is able to recall words and have subsequently influenced language assessment and treatment design. Emotion is another variable that may impact word retrieval, but has not been thoroughly investigated. PWA have previously demonstrated superior language performance for emotional compared to non- emotional stimuli on a range of language tasks including auditory comprehension,5,61 verbal pragmatics,9 repetition,60 and reading and writing,40 suggesting that emotion favorably impacts language processing for this population. There is sparse literature investigating the emotion facilitation effect in PWA in quantity and in scope, assessing only a limited number of language processes. Furthermore, there have been no attempts to integrate the variable of emotion into existing word retrieval models. There is a need to better understand the role emotion plays in language to improve our word retrieval models and subsequently inform clinical practice. To accomplish this, it will be important to understand the effect of emotion on word retrieval in neurologically-intact (NI) adults and to compare them to adults with aphasia. To fill the gaps discussed above, two experiments are proposed to investigate the effect of emotion on word retrieval in NI younger and older adults (Aim 1) and in PWA (Aim 2). Participants will engage in a series of single- word production tasks (object picture naming, action picture naming, object/action word reading, and object/action word repetition) that include positive, negative, and neutral stimuli to a) compare within-group differences among emotional valence groups, b) compare differences among language tasks, and c) compare between-group differences between younger and older adults and between PWA and age-matched NI controls. Potential moderating variables, including arousal and age, will be accounted for in the proposed project. In addition, a theory is presented to support our hypotheses, which considers contemporary word retrieval models. The fellowship training plan will include formalized courses and independent studies to enhance background knowledge in word retrieval and emotion processing, research design, and statistical analysis. In addition, the training plan will include workshops and other experiences aimed at improving scientific dissemination and grant writing skills. The research training will take place at a large, research-intensive university under the direction of a strong, well-matched mentorship team.

项目摘要/摘要 失语症是一种传播障碍，可能会在中风后发生，并影响大约三分之一的传播障碍 中风幸存者。失语症的标志性症状之一是异常或难以思考一个人想要的一词 使用（即单词检索）。由于失语症患者（PWA）的异常症患病率（PWA），许多人 评估和治疗方法集中在此症状上。选择适当的刺激很重要 诊断和治疗成功。如图或书面刺激的特征（例如单词频率或 成像性）影响人们能够回忆单词并随后影响语言的容易性 评估和治疗设计。情感是另一个可能影响单词检索的变量，但不是 彻底调查。 与非 - 情感刺激对包括听觉理解，5,61种口头语用学，9个语言任务的情感刺激，9 重复，60和阅读和写作，40表明情感对此有利影响语言处理 人口。有稀疏的文献调查了PWA在数量和范围中的情绪促进作用， 仅评估有限数量的语言过程。此外，没有尝试整合 情绪变量变成现有单词检索模型。有必要更好地理解情感的角色 使用语言来改善我们的单词检索模型，并随后为临床实践提供依据。完成 这是重要的是要了解情感对神经学（NI）成年人的单词检索的影响 并将他们与失语症的成年人进行比较。 为了填补上面讨论的空白，提出了两个实验来研究情绪对单词的影响 在NI年轻和老年人（AIM 1）和PWA中检索（AIM 2）。参与者将参与一系列单一 单词生产任务（对象图片命名，动作图片命名，对象/动作单词读数和 对象/动作单词重复），其中包括正，负和中性刺激与a）比较集团内部 情感价群体之间的差异，b）比较语言任务之间的差异，c）比较 年轻人和老年人之间以及PWA和年龄匹配的NI对照之间的差异。 在拟议的项目中将考虑潜在的调节变量，包括唤醒和年龄。在 此外，提出了一种理论来支持我们的假设，该假设考虑了当代单词检索模型。 奖学金培训计划将包括正式的课程和独立研究，以增强背景 单词检索和情感处理，研究设计和统计分析方面的知识。另外， 培训计划将包括旨在改善科学传播和授予的其他旨在改善科学传播的经验 写作技巧。研究培训将在一所大型研究密集于大学的指导下进行 一个强大，匹配的指导团队。