12th International Symposium on Bordetella

项目摘要/摘要：百日咳或百日咳曾被认为是一种 但它现在是疫苗可预防的最难控制的疾病之一。百日咳是 主要由革兰氏阴性病原体百日咳杆菌引起，但其他几种 波氏杆菌在人类和动物中都会引起类似的疾病。卷土重来 百日咳与向无细胞百日咳疫苗(DTaP和Tdap)的过渡有关 20世纪90年代初。自20世纪60年代以来，波尔德泰拉研究界组织了 国际会议为学员、医生、科学家、 流行病学家、公共卫生官员和疫苗制造商聚集在一起，专注于 问题齐头并进。国际研讨会在3点4分举行 年周期。波尔德泰拉国际研讨会有助于建立合作关系， 交流思想，确定优先事项，并为下一代提供培训机会 科学家的身份。在第11次研讨会上，有50个口头陈述和110张海报 由来自20个国家的196名与会者介绍。第十二次研讨会将于 布鲁塞尔大学将由Françoise Mascart教授和Camille Locht博士主持。这个 由11名国际知名科学家组成的组委会将直接参加 参与会议的策划和管理。预计第十二届研讨会将接待300人 参与者。会议议程包括：波尔德氏菌生物学、基因组学、进化、 流行病学、致病机制和致病因素、疾病和传播的动物模型、 对感染的免疫反应和免疫、疫苗设计以及其他重要的 主题。虽然有很多讨论细菌病原体的会议，但这是唯一的 专门关注波尔德泰拉的研讨会。为了支持下一代的发展 一代科学家，这个R13应用程序正在申请资金，以支持以下项目的旅行奖励 初级科学家(博士后和博士后)出席并在 2019年4月，第十二届国际波尔德泰拉研讨会。

Project Summary/Abstract: Pertussis or whooping cough was once considered a disease of the past but it is now one of the least controlled vaccine preventable diseases. Pertussis is primarily caused by the Gram negative pathogen, Bordetella pertussis, but several other Bordetellae cause similar diseases in humans as well as animals. The reemergence of pertussis correlates with the transition to the acellular pertussis vaccines (DTaP and Tdap) in the early 1990s. Since the 1960's the Bordetella research community has organized international meetings which provide an opportunity for trainees, physicians, scientists, epidemiologists, public health officials, and vaccine manufacturers to assemble and focus on the problems together to move forward. The International Symposium occurs on a three-four year cycle. The International Bordetella Symposium has served to build collaborations, exchange ideas, establish priorities, and facilitate training opportunities for the next generation of scientists. At the 11th symposium there were 50 oral presentations and 110 posters presented by 196 attendees from 20 total countries. The 12th Symposium will be held at Brussels University and will be hosted by Prof. Françoise Mascart and Dr. Camille Locht. The organizing committee made up of 11 internationally known scientists who will directly participate in the planning and administration of meeting. It is expected the 12th symposium will host 300 participants. The meeting agenda includes: Bordetella biology, genomics, evolution, epidemiology, pathogenesis and virulence factors, animal models of disease and transmission, immune responses to infection and immunization, vaccine design, as well as other important topics. While there are numerous meetings that discuss bacterial pathogens, this is the only symposium that exclusively focuses on Bordetella. In order to support development of the next generation of scientists, this R13 application is requesting funds to support travel awards for junior scientists (pre- and post-doctoral) to attend and present innovative research at the 12th International Bordetella Symposium in April 2019.