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NCCU-LCCC Partnership in Cancer Research

NCCU-LCCC 癌症研究合作伙伴关系

基本信息

批准号：
9761993
负责人：
MICHELER Ricardo RICHARDSON
金额：
$ 120.36万
依托单位：
NORTH CAROLINA CENTRAL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-29 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9761993
关键词：
Address Advanced Malignant Neoplasm Advisory Committees African American American Cancer Society Attention Biotechnology Cancer Biology Cancer Burden Cancer Research Project Clinical Collaborations Community Outreach Complex Comprehensive Cancer Center Disease Education Education and Outreach Educational process of instructing Effectiveness Environmental Exposure Eye Faculty Foundations Funding Genetic Genomics Goals Grant Health Promotion Health Sciences Health Services Accessibility Histopathology Human Incidence Infrastructure Institution Intervention Leadership Malignant Neoplasms Mentorship Minority Minority Recruitment Molecular Morbidity - disease rate National Cancer Institute North Carolina Outreach Research Pathway interactions Pilot Projects Population Population Sciences Positioning Attribute Predisposition Public Health Recurrence Research Research Infrastructure Research Institute Research Personnel Research Training Resources Scientist Socioeconomic Factors Students Tissues Training Treatment Failure U-Series Cooperative Agreements UNC Lineberger Comprehensive Cancer Center Underrepresented Students Universities anticancer research base cancer education cancer health disparity cancer therapy career caucasian American cohort community intervention education research experience graduate student health disparity health equity interest member minority communities minority health minority student minority undergraduate mortality outreach population based programs public health relevance recruit senior faculty theories training opportunity translational cancer research translational scientist undergraduate student

项目摘要

DESCRIPTION (provided by applicant) Abstract: The North Carolina Central University (NCCU) and the Lineberger Comprehensive Cancer Center (LCCC) at the University of North Carolina Chapel Hill (UNC-CH) will continue their effective and mutually beneficial partnership focusing on African-American health disparities. During the past 13 years NCI funding has firmly established the Partnership building on complementary institutional strengths, conducting molecular and population-based cancer research and training of junior faculty and students. This Comprehensive Partnership to Advance Cancer Health Equity (CPACHE) application builds upon the foundation already established through the previous U54 funding to meet the challenge of disparities in cancer incidence and mortality in North Carolina and the US through cancer research, education and community outreach. Our goals are to: (1) strengthen cancer research capacity at NCCU providing NCCU scientists mentorship and collaborative opportunities to compete for NCI grants; (2) enrich the capacity of NCCU and LCCC to further explore mechanisms underlying the disproportionate incidence of cancer mortality and morbidity between African Americans and Caucasian Americans, using both molecular and population-based approaches; (3) increase the number of NCCU scientists focused on cancer research as well as the education of minority undergraduate and graduate students in cancer research; (4) increase the faculty at the UNC LCCC focused on minority disparities research; and (5) create long-term collaborations between basic, public health, and translational scientists from NCCU and UNC LCCC. The strengths of each institution are uniquely positioned to overcome the weaknesses found in the other to achieve these priorities. Specific collaborative components of the proposal include: Two full and one pilot projects in community intervention and population science, one full and one pilot project in basic/translational cancer research in diseases with a higher incidence in African Americans, and 3 cores: Outreach, Research Education, and Histopathology. The partnership combines the expertise and resources of LCCC in population/public health sciences emphasizing disparities in North Carolina, genomics, cancer biology and cancer education and NCCU's demonstrated interest and faculty with minority health disparities research particularly in Durham NC, the state-funded NCCU units that allow faculty release from teaching and the emphasis on reaching minority populations and developing the careers of, faculty and students. These complementary institutional strengths will assure that the Partnership builds the infrastructure necessary for a lasting collaborative research, effective community outreach and a substantial contribution to our understanding of minority disparities.

摘要：北卡罗来纳中央大学（NCCU）和北卡罗来纳大学教堂山分校（UNC-CH）的Lineberger综合癌症中心（LCCC）将继续开展有效互利的合作伙伴关系，重点关注非裔美国人的健康差异。在过去的13年里，NCI的资金已经在互补的机构优势上建立了牢固的伙伴关系，开展了基于分子和人群的癌症研究，并培训了初级教师和学生。这项促进癌症健康公平的全面伙伴关系（CPACHE）应用建立在此前U54基金已经建立的基础上，该基金通过癌症研究、教育和社区外展来应对北卡罗来纳州和美国癌症发病率和死亡率差异的挑战。我们的目标是：(1)加强ncccu的癌症研究能力，为ncccu的科学家提供指导和合作机会，以竞争NCI的资助；(2)丰富NCCU和LCCC的能力，利用分子和人群为基础的方法，进一步探索非裔美国人和白种人之间不成比例的癌症死亡率和发病率的机制；(3)增加从事癌症研究的科研人员数量，加强对少数民族本科生和研究生的癌症研究教育；(4)增加北卡罗来纳大学LCCC专注于少数民族差异研究的师资队伍；(5)在NCCU和UNC LCCC的基础、公共卫生和转化科学家之间建立长期合作。每个机构的优势都具有独特的优势，可以克服对方的弱点，实现这些优先事项。该提案的具体合作组成部分包括：社区干预和人口科学方面的两个完整和一个试点项目，非洲裔美国人发病率较高的疾病的基础/转化癌症研究方面的一个完整和一个试点项目，以及3个核心项目：外展、研究教育和组织病理学。这一合作关系结合了LCCC在人口/公共卫生科学方面的专业知识和资源，强调北卡罗来纳州的差异，基因组学，癌症生物学和癌症教育，以及NCCU对少数民族健康差异研究的表现出的兴趣和教师，特别是在北卡罗来纳州达勒姆，国家资助的NCCU单位允许教师从教学中解脱出来，强调接触少数民族人口并发展教师和学生的职业生涯。这些互补的机构优势将确保伙伴关系建立持久的合作研究、有效的社区外展和对我们对少数群体差异的理解作出重大贡献所需的基础设施。