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NCCU-LCCC Partnership in Cancer Research

NCCU-LCCC 癌症研究合作伙伴关系

基本信息

批准号：
10247140
负责人：
MICHELER Ricardo RICHARDSON
金额：
$ 61.87万
依托单位：
NORTH CAROLINA CENTRAL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-29 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10247140
关键词：
Address Advanced Malignant Neoplasm Advisory Committees African American American Cancer Society Attention Biotechnology Cancer Biology Cancer Burden Cancer Research Project Clinical Collaborations Community Outreach Complex Comprehensive Cancer Center Disease Education Education and Outreach Educational process of instructing Effectiveness Environmental Exposure Eye Faculty Foundations Funding Genetic Genomics Goals Grant Health Promotion Health Sciences Health Services Accessibility Histopathology Human Incidence Infrastructure Institution Intervention Leadership Malignant Neoplasms Mentorship Minority Minority Recruitment Molecular Morbidity - disease rate National Cancer Institute North Carolina Outreach Research Pathway interactions Pilot Projects Population Population Sciences Positioning Attribute Predisposition Public Health Recurrence Research Research Infrastructure Research Institute Research Personnel Research Training Resources Scientist Socioeconomic Factors Students Tissues Training Treatment Failure U-Series Cooperative Agreements UNC Lineberger Comprehensive Cancer Center Underrepresented Students Universities anticancer research base cancer education cancer health disparity cancer therapy career caucasian American cohort community intervention education research experience graduate student health disparity health equity interest member minority communities minority health minority student minority undergraduate mortality outreach population based programs public health relevance recruit senior faculty theories training opportunity translational cancer research translational scientist undergraduate student

项目摘要

DESCRIPTION (provided by applicant) Abstract: The North Carolina Central University (NCCU) and the Lineberger Comprehensive Cancer Center (LCCC) at the University of North Carolina Chapel Hill (UNC-CH) will continue their effective and mutually beneficial partnership focusing on African-American health disparities. During the past 13 years NCI funding has firmly established the Partnership building on complementary institutional strengths, conducting molecular and population-based cancer research and training of junior faculty and students. This Comprehensive Partnership to Advance Cancer Health Equity (CPACHE) application builds upon the foundation already established through the previous U54 funding to meet the challenge of disparities in cancer incidence and mortality in North Carolina and the US through cancer research, education and community outreach. Our goals are to: (1) strengthen cancer research capacity at NCCU providing NCCU scientists mentorship and collaborative opportunities to compete for NCI grants; (2) enrich the capacity of NCCU and LCCC to further explore mechanisms underlying the disproportionate incidence of cancer mortality and morbidity between African Americans and Caucasian Americans, using both molecular and population-based approaches; (3) increase the number of NCCU scientists focused on cancer research as well as the education of minority undergraduate and graduate students in cancer research; (4) increase the faculty at the UNC LCCC focused on minority disparities research; and (5) create long-term collaborations between basic, public health, and translational scientists from NCCU and UNC LCCC. The strengths of each institution are uniquely positioned to overcome the weaknesses found in the other to achieve these priorities. Specific collaborative components of the proposal include: Two full and one pilot projects in community intervention and population science, one full and one pilot project in basic/translational cancer research in diseases with a higher incidence in African Americans, and 3 cores: Outreach, Research Education, and Histopathology. The partnership combines the expertise and resources of LCCC in population/public health sciences emphasizing disparities in North Carolina, genomics, cancer biology and cancer education and NCCU's demonstrated interest and faculty with minority health disparities research particularly in Durham NC, the state-funded NCCU units that allow faculty release from teaching and the emphasis on reaching minority populations and developing the careers of, faculty and students. These complementary institutional strengths will assure that the Partnership builds the infrastructure necessary for a lasting collaborative research, effective community outreach and a substantial contribution to our understanding of minority disparities.

描述（由申请人提供）摘要：北卡罗莱纳中央大学 (NCCU) 和北卡罗莱纳大学教堂山分校 (UNC-CH) 的莱恩伯格综合癌症中心 (LCCC) 将继续建立有效和互利的合作伙伴关系，重点关注非裔美国人的健康差异。在过去的 13 年里，NCI 的资助牢固地建立了合作伙伴关系，建立在互补的机构优势、开展分子和人群癌症研究以及对初级教师和学生的培训的基础上。这一促进癌症健康公平的全面合作伙伴关系 (CPACHE) 申请建立在之前 U54 资助所建立的基础上，旨在通过癌症研究、教育和社区外展应对北卡罗来纳州和美国癌症发病率和死亡率差异的挑战。我们的目标是：(1) 加强 NCCU 的癌症研究能力，为 NCCU 科学家提供指导和合作机会，以竞争 NCI 资助； (2) 增强 NCCU 和 LCCC 的能力，利用分子和基于人口的方法，进一步探索非洲裔美国人和白人美国人之间癌症死亡率和发病率不成比例的机制； (3) 增加国立政治大学专注于癌症研究的科学家数量以及少数民族本科生和研究生癌症研究的教育； (4) 增加北卡罗来纳大学 LCCC 专注于少数群体差异研究的师资队伍； (5) 在 NCCU 和 UNC LCCC 的基础科学家、公共卫生科学家和转化科学家之间建立长期合作。每个机构都具有独特的优势，能够克服对方的弱点，从而实现这些优先事项。该提案的具体合作组成部分包括：社区干预和人口科学方面的两个完整项目和一个试点项目，非裔美国人发病率较高疾病的基础/转化癌症研究的一个完整项目和一个试点项目，以及三个核心项目：外展、研究教育和组织病理学。该合作伙伴关系结合了 LCCC 在人口/公共卫生科学方面的专业知识和资源，强调北卡罗来纳州的差异、基因组学、癌症生物学和癌症教育，以及 NCCU 对少数民族健康差异研究表现出的兴趣和教员，特别是在北卡罗来纳州达勒姆，国家资助的 NCCU 单位允许教师从教学中解脱出来，并强调接触少数族裔并发展教师和学生的职业生涯。这些互补的机构优势将确保该伙伴关系建立必要的基础设施，以进行持久的合作研究、有效的社区外展以及对我们对少数族裔差异的理解做出重大贡献。