Administrative Core

管理核心-项目摘要 密歇根州化合物鉴定发展核心（MCIDC）将使用综合计算和 实验方法，以推进与化合物鉴定领域有关的科学 代谢组学在共同基金代谢组学计划的第二阶段，MCIDC将 与合作体成员和广大科学界分享这些努力的成果。 MCIDC调查人员的工作将主要利用密歇根州现有的基础设施进行。 代谢组学和肥胖中心（MMOC），最近更名为密歇根代谢组学中心（MMC）， 负责监督共同基金支持的密歇根州区域综合代谢资源核心 (U24)，儿童健康暴露分析资源（U2 C）和物理分子传感器 活动（MoTrPAC（U24））赠款。MCIDC行政核心的总体目标是协调 MCIDC内的活动，MMC的较大代谢组学基础设施，其他CIDCs，NIH 共同基金代谢组学计划和更大的代谢组学社区。 为实现这一目标，行政核心将：提供基础设施，以协调和整合研究 在MCIDC计算和实验核心之间，并促进它们的相互作用;管理人员， MCIDC及其在具体项目中的作用;确保提供所需的领导和所需的资源 到计算和实验核心;充当与其他实体协调的接口。 共同基金代谢组学联盟和更广泛的研究界;监督MCIDC的预算 评估各核心在所需化合物识别任务方面的进展情况， 查明并消除任何障碍，以稳步实现MCIDC的科学目标。

Administrative Core - Project Summary The Michigan Compound Identification Development Core (MCIDC) will use integrated computational and experimental approaches to advance sciences pertaining to compound identification in the field of metabolomics. Working within the second stage of the Common Fund Metabolomics Program, the MCIDC will share the results of these efforts with consortium members and with the larger scientific community. Work by MCIDC investigators will be performed largely using the existing infrastructure of the Michigan Metabolomics and Obesity Center (MMOC), recently renamed the Michigan Metabolomics Center (MMC), which oversees the Common Fund-supported Michigan Regional Comprehensive Metabolic Resource Core (U24), the Children's Health Exposure Analysis Resource (U2C) and the Molecular Transducers of Physical Activity (MoTrPAC (U24)) grant. The overall goal of the Administrative Core MCIDC is to coordinate the activities within the MCIDC, the larger metabolomics infrastructure of the MMC, the other CIDCs, the NIH Common Fund Metabolomics Program and the larger metabolomics community. To achieve this goal, the administrative core will: provide infrastructure to coordinate and integrate research between the MCIDC computational and experimental cores and facilitate their interaction; manage personnel in MCIDC and their roles within specific projects; ensure required leadership and required resources are available to the computational and experimental cores; act as an interface for coordination with other entities of the Common Funds Metabolomics Consortium and the broader research community; oversee MCIDC's budget and expenditures; and assess ongoing progress of the cores on required compound identification tasks, and identify and remove any barriers to steady progress towards completion of MCIDC's scientific objectives.