T21RS meeting June 2019 Barcelona meeting grant

T21RS 会议 2019 年 6 月 巴塞罗那会议补助金

• 批准号: 9763218
• 负责人: ANITA BHATTACHARYYA
• 金额: $ 1.75万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-05-15 至 2020-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9763218
• 关键词: Address; Alzheimer' s Disease; American; Applied Research; Award; Basic Science; Brain; Cells; Chicago; Chromosomes, Human, Pair 21; Clinical Research; Clinical Trials; Cognition; Cognitive deficits; Collaborations; Communication; Country; Defect; Down Syndrome; Ethnic Origin; Europe; Family; Foundations; Funding; Future; Genetic; Genetic Research; Glean; Goals; Grant; Human; Impairment; Individual; Intellectual functioning disability; Intelligence; International; Journals; Knowledge; Laboratories; Museums; Nerve Degeneration; Neurobiology; Paris, France; Participant; Postdoctoral Fellow; Predisposition; Premature aging syndrome; Public Health; Request for Applications; Research; Research Personnel; Scientist; Societies; Spain; Structural defect; Students; Training and Education; Translating; Translational Research; Travel; Visit; base; career; design; developmental disease; developmental genetics; effective therapy; graduate student; improved; innovation; interest; knowledge base; meetings; member; middle age; neuron development; neuropathology; next generation; novel; posters; programs; science museum; success; symposium; therapeutic target; transcriptomics

Down syndrome (DS) is caused by the inheritance of three rather than the expected two copies of chromosome 21, or trisomy 21. It is characterized by specific structural abnormalities in the brain, by a range of cognitive deficits and intellectual disability, and by a tremendous susceptibility to develop Alzheimer’s dementia by middle age. The rapid pace of progress in DS research that has taken place in the last few years demand effective communication between scientists and clinicians working in this field in order to take basic research discoveries from the laboratory to clinical trials. Advances in DS research highlight the need to bring young scientists into this field. This application requests funding to cover travel expenses of American-based junior investigators, postdoctoral fellows and graduate students to attend the Third International conference of the Trisomy 21 Research Society (T21RS). Participants will include established DS and non-DS investigators whose research directly or indirectly informs critical aspects of DS cognition, neuropathology, translational opportunities and clinical trials. The meeting will take place in Barcelona, Spain from June 6 to June 9, 2019. We anticipate that this conference will lead to fruitful discussions and novel collaborations that are essential to define the future of DS research.

唐氏综合症（DS）是由三个而不是预期的两个染色体拷贝遗传引起的 21或21三体。它的特点是大脑中特定的结构异常，一系列的认知功能障碍， 缺陷和智力残疾，以及在中年时发展为阿尔茨海默氏痴呆症的巨大易感性， 年龄在过去几年中，DS研究的快速进展需要有效的 在这个领域工作的科学家和临床医生之间的交流，以采取基础研究发现 从实验室到临床试验。DS研究的进展突出了将年轻科学家带入 该领域这项申请要求提供资金，以支付美国初级调查员的差旅费， 博士后研究员和研究生参加第三届国际会议的三体21 研究学会（T21RS）。参与者将包括已建立的DS和非DS研究者，他们的研究 直接或间接地告知DS认知，神经病理学，翻译机会和 临床试验会议将于2019年6月6日至6月9日在西班牙巴塞罗那举行。我们预计 这次会议将导致富有成效的讨论和新的合作，这是必不可少的定义未来的 DS研究。