Strengthening Research Integrity Oversight and Ethical Review of Critical HIV Research in China

加强中国艾滋病毒关键研究的研究诚信监督和伦理审查

基本信息

项目摘要

PROJECT SUMMARY/ABSTRACT Scientific research capacity has grown enormously in China in recent years, and China has since become the largest contributor to the literature. However, recent discoveries of research misconduct, which have had a negative impact on Chinese scientists and their US collaborators, related to inadequate ethical review, neglect for human subjects protections, and publication fraud have highlighted China's under-developed research ethics capacity and infrastructure. China must act now to instill the principles of responsible conduct of research (RCR) in its next generation of scientists. The National Center for AIDS/STD Control and Prevention (NCAIDS) at the Chinese Center for Disease Control and Prevention (China CDC) has a long history of conducting critical HIV research in priority areas and is dedicated to continuing this mission into the future. Moreover, it is committed to leading the way for China in elevating research integrity to the international standard, not only by serving as an example, but also by helping other domestic institutions improve in this area. The capacity building strategies proposed herein are crucial next steps toward achieving this broader, long-term goal, and are also in line with the goal of the Fogarty International Center (FIC) HIV Research Training Program “to strengthen the human capacity to contribute to the ability of institutions in low- and middle-income countries (LMIC) to conduct HIV- related research on the evolving HIV-related epidemics in their country and to compete independently for research funding.” Building on existing institutional structures and resources at NCAIDS, China CDC, 2 aims are proposed. The proposal's first aim is to strengthen research integrity oversight of manuscripts at NCAIDS and at Anhui Medical University (AMU) and Kunming Medical University (KMU). To achieve this aim, 3 activities are proposed: (1) publication ethics workshop, where researchers at all levels will receive training on issues including plagiarism (how to avoid, detect, and remedy it), acceptable citation practices, and institutional and international expectations for ethical publication, (2) publication ethics case study e-learning modules will be developed and continually be updated to cover new cases and/or new forms of ethics violations, and (3) internal pre-submission manuscript review, a new process that will be developed and launched for the purpose of evaluating manuscripts The proposal's second aim is to strengthen ethical review of research proposals for the protection of human subjects at NCAIDS and AMU and KMU. To accomplish this aim, an additional 2 activities are proposed: (4) institutional review board (IRB) apprenticeships, whereby IRB members from AMU and KMU spend 3 days at NCAIDS working directly with NCAIDS IRB members and (5) IRB workshops, where NCAIDS AMU and KMU IRB members attend each other's IRB meetings and then put on a workshop-style event where critical review and for science quality, writing quality, and integrity of reporting, ensuring compliance to ethical standards. suggestions on areas of potential improvement are provided.
项目摘要/摘要 近年来,中国的科研能力有了很大提高,中国从此成为 文学作品的最大贡献者。然而,最近发现的研究不端行为,已经产生了 对中国科学家和他们的美国合作者的负面影响,与伦理审查不足、忽视有关 对于人体受试者的保护,以及发表论文造假,突显了中国研究伦理的欠发达 容量和基础设施。中国现在必须行动起来,灌输负责任的研究行为原则。 在其下一代科学家中。国家艾滋病/性病控制和预防中心(NCAIDS) 中国疾病预防控制中心(中国疾控中心)在处理危重艾滋病病毒方面有很长的历史 在优先领域进行研究,并致力于在未来继续这项任务。此外,它是 致力于 在将研究诚信提升到国际标准方面,中国走在了前面,不仅是通过担任 例如,还通过帮助其他国内机构改进这一领域。 能力建设战略 在此提出的是实现这一更广泛的长期目标的关键下一步,也符合 福格蒂国际中心(FIC)艾滋病毒研究培训计划的目标是“加强人类 促进低收入和中等收入国家机构开展艾滋病毒-- 关于本国艾滋病毒相关疫情演变的相关研究,并独立竞争 研究经费。“在NCAID现有机构结构和资源的基础上,中国疾控中心的2个目标是 建议。 该提案的第一个目标是加强对NCAID和ACT手稿的研究完整性监督 安徽医科大学(AMU)和昆明医科大学(KMU)。 为了实现这一目标,有3项活动 拟议:(1)出版道德问题讲习班,各级研究人员将接受关于以下问题的培训 剽窃(如何避免、发现和补救),可接受的引用做法,以及机构和国际 对道德出版物的期望,(2)将开发出版物道德案例研究电子学习单元,并 不断更新,以涵盖新案件和/或新形式的违反道德行为;以及(3)内部提交前 审稿,将开发和启动的一种新的程序,目的是评估手稿 这个 提案的第二个目标是加强对保护人类受试者的研究提案的伦理审查 在NCAIDS、AMU和KMU。为实现这一目标,建议开展另外两项活动:(4)体制活动 审查委员会(IRB)学徒制,来自AMU和KMU的IRB成员在NCAID停留3天 直接与NCAIDSIRB成员合作和(5)IRB研讨会,NCAIDSAMU和KMU IRB 成员彼此参加IRB会议,然后举行研讨会式的活动,在那里进行批判性审查和 对于科学质量、写作质量和报道的完整性,确保遵守道德标准。 对可能改进的领域提出了建议。

项目成果

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ZUNYOU WU其他文献

ZUNYOU WU的其他文献

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{{ truncateString('ZUNYOU WU', 18)}}的其他基金

Strengthening Research Integrity Oversight and Ethical Review of Critical HIV Research in China
加强中国艾滋病毒关键研究的研究诚信监督和伦理审查
  • 批准号:
    10018125
  • 财政年份:
    2019
  • 资助金额:
    $ 9.94万
  • 项目类别:
Technical Collaboration with the People's Republis of China on Innovative Approac
与中华人民共和国就创新方法进行技术合作
  • 批准号:
    8848607
  • 财政年份:
    2014
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    7645997
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8309917
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8138630
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    7919345
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8334361
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8530746
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    7690376
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
China Multidisciplinary AIDS Prevention Training Program
中国艾滋病多学科预防培训项目
  • 批准号:
    6780164
  • 财政年份:
    2004
  • 资助金额:
    $ 9.94万
  • 项目类别:

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