Strengthening Research Integrity Oversight and Ethical Review of Critical HIV Research in China

加强中国艾滋病毒关键研究的研究诚信监督和伦理审查

基本信息

项目摘要

PROJECT SUMMARY/ABSTRACT Scientific research capacity has grown enormously in China in recent years, and China has since become the largest contributor to the literature. However, recent discoveries of research misconduct, which have had a negative impact on Chinese scientists and their US collaborators, related to inadequate ethical review, neglect for human subjects protections, and publication fraud have highlighted China's under-developed research ethics capacity and infrastructure. China must act now to instill the principles of responsible conduct of research (RCR) in its next generation of scientists. The National Center for AIDS/STD Control and Prevention (NCAIDS) at the Chinese Center for Disease Control and Prevention (China CDC) has a long history of conducting critical HIV research in priority areas and is dedicated to continuing this mission into the future. Moreover, it is committed to leading the way for China in elevating research integrity to the international standard, not only by serving as an example, but also by helping other domestic institutions improve in this area. The capacity building strategies proposed herein are crucial next steps toward achieving this broader, long-term goal, and are also in line with the goal of the Fogarty International Center (FIC) HIV Research Training Program “to strengthen the human capacity to contribute to the ability of institutions in low- and middle-income countries (LMIC) to conduct HIV- related research on the evolving HIV-related epidemics in their country and to compete independently for research funding.” Building on existing institutional structures and resources at NCAIDS, China CDC, 2 aims are proposed. The proposal's first aim is to strengthen research integrity oversight of manuscripts at NCAIDS and at Anhui Medical University (AMU) and Kunming Medical University (KMU). To achieve this aim, 3 activities are proposed: (1) publication ethics workshop, where researchers at all levels will receive training on issues including plagiarism (how to avoid, detect, and remedy it), acceptable citation practices, and institutional and international expectations for ethical publication, (2) publication ethics case study e-learning modules will be developed and continually be updated to cover new cases and/or new forms of ethics violations, and (3) internal pre-submission manuscript review, a new process that will be developed and launched for the purpose of evaluating manuscripts The proposal's second aim is to strengthen ethical review of research proposals for the protection of human subjects at NCAIDS and AMU and KMU. To accomplish this aim, an additional 2 activities are proposed: (4) institutional review board (IRB) apprenticeships, whereby IRB members from AMU and KMU spend 3 days at NCAIDS working directly with NCAIDS IRB members and (5) IRB workshops, where NCAIDS AMU and KMU IRB members attend each other's IRB meetings and then put on a workshop-style event where critical review and for science quality, writing quality, and integrity of reporting, ensuring compliance to ethical standards. suggestions on areas of potential improvement are provided.
项目概要/摘要 近年来,中国的科研能力大幅提升,中国已成为世界第一强国。 文学的最大贡献者。然而,最近发现的科研不端行为已经引起了 对中国科学家及其美国合作者的负面影响,与伦理审查不充分、忽视有关 人类受试者保护和发表欺诈凸显了中国研究道德的欠发达 能力和基础设施。中国必须立即采取行动,灌输负责任的研究行为(RCR)原则 在下一代科学家中。国家艾滋病/性病预防控制中心 (NCAIDS) 中国疾病预防控制中心(中国疾控中心)在开展危重艾滋病防治工作方面有着悠久的历史 重点领域的研究,并致力于在未来继续这一使命。而且,它是 承诺 引领中国将科研诚信提升至国际标准,而不仅仅是充当 例如,还可以帮助其他国内机构在这一领域进行改进。 能力建设策略 本文提出的步骤是实现这一更广泛的长期目标的关键后续步骤,并且也符合 福格蒂国际中心 (FIC) 艾滋病毒研究培训计划的目标是“加强人类 提高低收入和中等收入国家(LMIC)机构开展艾滋病毒防治工作的能力 对该国不断变化的艾滋病毒相关流行病进行相关研究,并独立竞争 研究经费。”中国疾病预防控制中心、性艾中心现有机构结构和资源的基础上,有两个目标: 建议的。 该提案的首要目标是加强性艾中心和国家艾滋病中心对稿件的研究诚信监督。 安徽医科大学(AMU)和昆明医科大学(KMU)。 为实现这一目标,开展了 3 项活动 提议:(1) 出版道德研讨会,各级研究人员将接受以下问题的培训: 抄袭(如何避免、检测和补救)、可接受的引用实践以及机构和国际 对出版道德的期望,(2) 将开发出版道德案例研究电子学习模块 不断更新以涵盖新案例和/或新形式的道德违规行为,以及 (3) 内部预提交 稿件审查,为评估稿件而开发和启动的新流程 这 该提案的第二个目标是加强对保护人类受试者的研究提案的伦理审查 在性艾中心、AMU 和 KMU。为实现这一目标,建议开展另外 2 项活动:(4) 机构 审查委员会 (IRB) 学徒期,来自 AMU 和 KMU 的 IRB 成员在性艾中心度过 3 天 直接与 NCAIDS IRB 成员合作以及 (5) IRB 研讨会,其中 NCAIDS AMU 和 KMU IRB 成员们参加彼此的 IRB 会议,然后举办研讨会式的活动,进行严格审查和 科学质量、写作质量和报告的完整性,确保遵守道德标准。 提供了有关潜在改进领域的建议。

项目成果

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ZUNYOU WU其他文献

ZUNYOU WU的其他文献

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{{ truncateString('ZUNYOU WU', 18)}}的其他基金

Strengthening Research Integrity Oversight and Ethical Review of Critical HIV Research in China
加强中国艾滋病毒关键研究的研究诚信监督和伦理审查
  • 批准号:
    10018125
  • 财政年份:
    2019
  • 资助金额:
    $ 9.94万
  • 项目类别:
Technical Collaboration with the People's Republis of China on Innovative Approac
与中华人民共和国就创新方法进行技术合作
  • 批准号:
    8848607
  • 财政年份:
    2014
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    7645997
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8309917
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8138630
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8334361
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    7919345
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    8530746
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
PREVENTION OF SECONDARY TRANSMISSION AMONG MOST-AT-RISK POPULATIONS
预防高危人群的二次传播
  • 批准号:
    7690376
  • 财政年份:
    2008
  • 资助金额:
    $ 9.94万
  • 项目类别:
China Multidisciplinary AIDS Prevention Training Program
中国艾滋病多学科预防培训项目
  • 批准号:
    6780164
  • 财政年份:
    2004
  • 资助金额:
    $ 9.94万
  • 项目类别:

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