Integration of Virtual Reality Mindfulness Application Within a Mobile-Based Recovery Platform to Support Rehab and Post-Rehab Engagement

将虚拟现实正念应用程序集成到基于移动的恢复平台中，以支持康复和康复后参与

• 批准号: 9898123
• 负责人: Beau Mann
• 金额: $ 22.5万
• 依托单位: SOBER GRID, INC.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2021-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9898123
• 关键词: Aftercare; Alcohol dependence; Alcohol or Other Drugs use; Alcohols; Android; Caring; Cellular Phone; Clinic; Clinical; Communities; Coupled; Development; Drug Addiction; Enhancement Technology; Feedback; Focus Groups; Health; Health Services Accessibility; Healthcare Systems; Home environment; Immersion Investigative Technique; Individual; Informal Social Control; Inpatients; Intervention; Medical Device; Mental Health; Methods; Mission; Opioid; Outcome; Participant; Patients; Personal Satisfaction; Persons; Phase; Population; Preparation; Production; Protocols documentation; Psyche structure; Randomized; Recovery; Relapse; Research; Resources; Scientist; Services; Structure; Substance Use Disorder; Technology; Testing; Therapeutic; Therapeutic Effect; Time; Training; Training Support; Treatment Efficacy; Universities; Visual; Well in self; addiction; base; cost; cost effective; design; evidence base; experience; improved; innovation; inpatient service; machine learning algorithm; member; mindfulness; mindfulness intervention; mobile application; new technology; peer; peer coaching; peer support; prototype; relapse prediction; relapse risk; sobriety; social; sound frequency; success; telehealth; therapy design; treatment as usual; treatment program; virtual reality

ABSTRACT Post-treatment substance use disorder (SUD) relapse rates are high (40-60% at one year), with relapse occurring early (median time to relapse 1-3 months), indicating that the transition period from inpatient care to the home environment is particularly challenging for patients seeking sobriety. Telehealth and VR technologies have the ability to greatly increase the accessibility of highly engaging recovery support. Combining these two approaches provides a unique opportunity to create a highly engaging, cost-effective take home recovery support solution targeting the critical transition from inpatient care. Sober Grid proposes to leverage its existing highly accessible social and peer coaching mobile recovery app, to develop a convenient and cost-effective integrated take-home combined VR and professional peer coaching recovery support intervention (RecoVRi) that begins in the inpatient clinic. RecoVRi is designed to increase engagement with recovery therapy during the critical transition from inpatient to home, thereby reducing the risk of relapse and associated health and monetary costs. Sober Grid is collaborating with TRIPP, Inc. to utilize TRIPP’s immersive wellness platform. The design of the TRIPP experience leverages a large body of existing research on the use of VR technology in the mental wellness arena and utilizes proven mindfulness structures, targeted sound frequencies, visuals and interactions that have a multiplicative effect when administered through immersion. The Sober Grid Network will create a support wrapper to the VR experience that facilitates access to crisis management experts and community for the person in early recovery. The unique combination of a personalized and targeted self-regulation toolkit and community and professional support is a key differentiator for this service. In phase I of the project, we will develop and pilot test a proof-of-concept RecoVRi VR-mindfulness protocol and intervention to ascertain feasibility and acceptability (Aim 1). In phase II of the project, a production-quality intervention will be developed with new VR content created by the TRIPP development team specifically targeting themes supporting recovery from alcohol, stimulant and opioid SUD separately (Aim 2). We will then test post-treatment recovery support engagement in the RecoVRi intervention in comparison to treatment as usual in a randomized comparison trial involving 80 patients receiving inpatient treatment and transitioning to the home setting (Aim 3). Over the span of both phases, we will seek regulatory guidance from the FDA in order to attain clearance for use of the RecoVRi intervention as a therapeutic medical device (Aim 4).

摘要 治疗后物质使用障碍（SUD）复发率很高（一年时为40-60%）， 早期发生（复发的中位时间为1-3个月），表明从住院治疗到 家庭环境对于寻求清醒的患者来说尤其具有挑战性。远程医疗和VR技术 有能力大大提高高参与度恢复支持的可访问性。结合这两 方法提供了一个独特的机会，以创建一个高度参与，具有成本效益的带回家的恢复支持 针对从住院治疗的关键过渡的解决方案。 Sober Grid建议利用其现有的高度可访问的社交和同伴教练移动的恢复应用程序， 开发一个方便和具有成本效益的集成带回家结合虚拟现实和专业的同伴教练 康复支持干预（CARVRI），从住院诊所开始。VIPVRi旨在提高 在从住院病人到家庭的关键过渡期间参与恢复治疗，从而降低风险 以及相关的健康和金钱成本。Sober Grid正在与TRIPP，Inc.利用 TRIPP的沉浸式健康平台。TRIPP体验的设计利用了现有的大量 研究虚拟现实技术在心理健康竞技场中的应用，并利用经过验证的正念结构， 有针对性的声音频率，视觉和互动，具有倍增效应时，管理通过 沉浸式。Sober Grid Network将为VR体验创建一个支持包装， 危机管理专家和社区的人在早期恢复。独特的组合， 个性化和有针对性的自我监管工具包以及社区和专业支持是一个关键的区别 对于这项服务。 在该项目的第一阶段，我们将开发和试点测试概念验证VR-VR-正念协议， （一）可行性和可接受性（目标1）。在项目的第二阶段， 干预将使用TRIPP开发团队专门创建的新VR内容进行开发 分别针对支持从酒精、兴奋剂和阿片类SUD中康复的主题（目标2）。然后我们将 与治疗相比，测试治疗后恢复支持在BMPVRi干预中的参与， 在随机对照试验中常见，该试验涉及80例接受住院治疗并过渡到 家庭环境（目标3）。在这两个阶段的跨度内，我们将寻求FDA的监管指导， 获得批准，允许将ARMVRi介入器械用作治疗性医疗器械（目标4）。