Enhancing the impact of behavioral pain management on MAT outcomes
增强行为疼痛管理对 MAT 结果的影响
基本信息
- 批准号:9892107
- 负责人:
- 金额:$ 323.75万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-09-28 至 2024-05-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdherenceAdoptedAdverse eventAlcohol or Other Drugs useAwardBehavior TherapyBehavioralBuprenorphineCaringCommunitiesComorbidityComplementary HealthDataEffectivenessFocus GroupsFrequenciesFundingFutureGoalsGrantHealth PersonnelHealth Services AccessibilityHealthcare SystemsHigh PrevalenceHybridsIndividualIntegrative MedicineInterventionInterviewLengthLinkLiteratureMeasurementMediationMediator of activation proteinMethodologyMethodsMichiganOpioidOutcomeOverdosePainPain managementParticipantPatient RecruitmentsPatientsPharmaceutical PreparationsPhasePopulationProviderPsychosocial Assessment and CarePublic HealthRandomizedReportingResearchRiskSamplingShapesSiteSubstance Use DisorderTelephoneTestingTimeTreatment outcomeUnited StatesUnited States National Institutes of HealthUnited States Substance Abuse and Mental Health Services AdministrationVeteransVulnerable PopulationsWorkadverse outcomebasechronic painchronic pain patientdesignevidence basefollow up assessmentfollow-uphigh risk populationimplementation scienceimprovedimproved outcomemedication-assisted treatmentopioid epidemicopioid therapyopioid useopioid use disorderpatient populationpilot trialpsychosocialrandomized trialrecruitresponsetreatment adherencetreatment as usual
项目摘要
Project Summary/Abstract
In order to address the opioid epidemic in the United States, it is essential to improve outcomes in individuals
with opioid use disorders (OUD). Medication Assisted Treatments (MAT) can be extremely helpful for those
with OUDs but poor treatment retention on MAT diminishes the potential positive impact of these interventions.
One factor that has been linked to poorer outcomes in those with OUD and may undermine treatment
adherence is chronic pain, which is reported in the majority of those receiving OUD treatment. Psychosocial
interventions for pain have been effective in patients with chronic pain and substance use disorders, but these
interventions have not been thoroughly examined in the OUD population receiving MAT. The study team
received a recent grant from the National Center for Complementary and Integrative Health to refine and adapt
a psychosocial pain management intervention (PPMI) to be delivered by telephone for patients with OUD
receiving MAT. After finalizing the intervention this funded study will conduct a randomized trial (N=100)
comparing telephone-based PPMI approach to EUC to assess the impact of randomization to PPMI on MAT
retention, pain level, pain-related functioning, and frequency of opioid use. However, more work is needed to
understand the potential applicability of this intervention to other high-risk groups, study the longer-term impact
of PPMI and gather data to inform the implementation of PPMI in MAT patients. In particular, understanding
methods to reach Veterans is important because of consistent evidence highlighting the high prevalence of
OUDs and opioid-related adverse events, including overdose, in Veterans. The proposed work addresses the
gaps in the literature and builds on the ongoing, funded project by: (aim 1) adding additional recruitment sites
at the VA Ann Arbor Healthcare System (100 additional participants or a total N of 200 when combined with the
ongoing study); (aim 2) extending the measurement of longer-term outcomes by adding follow-up assessments
at 6-, 9- and 12-months for the entire sample (N=200); (aim 3) facilitating the rapid implementation of results by
gathering qualitative data from key stakeholders including MAT treatment providers (N=15) and patients who
received the PPMI intervention (N=20 participants recruited at the end of the trial). This work will provide a
robust test of the PPMI intervention to help enhance MAT outcomes in a larger and more-representative group
of participants while also paving the way for future implementation of interventions to improve MAT retention.
项目总结/摘要
为了解决美国的阿片类药物流行病,必须改善个人的结果
阿片类药物使用障碍(OUD)药物辅助治疗(MAT)对那些
OUD患者,但MAT的治疗保留较差,降低了这些干预措施的潜在积极影响。
一个与OUD患者预后较差有关的因素可能会破坏治疗
坚持是慢性疼痛,这是在大多数接受OUD治疗的患者中报告的。心理社会
疼痛干预措施对慢性疼痛和物质使用障碍患者有效,但这些
在接受MAT的OUD人群中,尚未彻底检查干预措施。研究团队
最近收到了国家补充和综合健康中心的一笔赠款,
通过电话为OUD患者提供心理社会疼痛管理干预(PPMI)
接收MAT。在最终确定干预措施后,该资助研究将进行随机试验(N=100)
将基于电话的PPMI方法与EUC进行比较,以评估PPMI随机化对MAT的影响
保留,疼痛水平,疼痛相关功能和阿片类药物使用频率。然而,还需要做更多的工作,
了解这种干预措施对其他高危人群的潜在适用性,研究其长期影响,
并收集数据,为MAT患者实施PPMI提供信息。特别是,理解
接触退伍军人的方法很重要,因为有一致的证据表明,
OUD和阿片类药物相关的不良事件,包括过量,退伍军人。拟议的工作涉及
文献中的空白,并通过以下方式在正在进行的供资项目基础上再接再厉:(目标1)增加更多的招募地点
在VA安阿伯医疗保健系统(100名额外参与者或当与
(目标2)通过增加后续评估,扩大长期结果的衡量
在6个月、9个月和12个月时对整个样本(N=200)进行评估;(目标3)通过以下方式促进结果的快速实施
收集关键利益相关者的定性数据,包括MAT治疗提供者(N=15)和
接受PPMI干预(在试验结束时招募的N=20名参与者)。这项工作将提供
对PPMI干预措施进行强有力的测试,以帮助在更大且更具代表性的群体中增强MAT结果
同时也为今后采取干预措施提高MAT成绩铺平了道路。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
MARK A. ILGEN其他文献
MARK A. ILGEN的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('MARK A. ILGEN', 18)}}的其他基金
Facilitating use of the National Suicide Prevention Lifeline in Alcohol Patients
促进酒精患者使用国家自杀预防生命线
- 批准号:
10228104 - 财政年份:2019
- 资助金额:
$ 323.75万 - 项目类别:
Facilitating use of the National Suicide Prevention Lifeline in Alcohol Patients
促进酒精患者使用国家自杀预防生命线
- 批准号:
10659125 - 财政年份:2019
- 资助金额:
$ 323.75万 - 项目类别:
Facilitating use of the National Suicide Prevention Lifeline in Alcohol Patients
促进酒精患者使用国家自杀预防生命线
- 批准号:
10451764 - 财政年份:2019
- 资助金额:
$ 323.75万 - 项目类别:
Psychosocial pain management to improve opioid use disorder treatment outcomes
心理社会疼痛管理可改善阿片类药物使用障碍的治疗结果
- 批准号:
9982460 - 财政年份:2018
- 资助金额:
$ 323.75万 - 项目类别:
Psychosocial pain management to improve opioid use disorder treatment outcomes
心理社会疼痛管理可改善阿片类药物使用障碍的治疗结果
- 批准号:
10020320 - 财政年份:2018
- 资助金额:
$ 323.75万 - 项目类别:
Improving Outcomes among Medical/Surgical Inpatients with Alcohol Use Disorders
改善酒精使用障碍内科/外科住院患者的治疗效果
- 批准号:
9981433 - 财政年份:2017
- 资助金额:
$ 323.75万 - 项目类别:
相似海外基金
An innovative, AI-driven prehabilitation platform that increases adherence, enhances post-treatment outcomes by at least 50%, and provides cost savings of 95%.
%20创新、%20AI驱动%20康复%20平台%20%20增加%20依从性、%20增强%20治疗后%20结果%20by%20at%20至少%2050%、%20和%20提供%20成本%20节省%20of%2095%
- 批准号:
10057526 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Grant for R&D
Improving Repositioning Adherence in Home Care: Supporting Pressure Injury Care and Prevention
提高家庭护理中的重新定位依从性:支持压力损伤护理和预防
- 批准号:
490105 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Operating Grants
I-Corps: Medication Adherence System
I-Corps:药物依从性系统
- 批准号:
2325465 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Standard Grant
Unintrusive Pediatric Logging Orthotic Adherence Device: UPLOAD
非侵入式儿科记录矫形器粘附装置:上传
- 批准号:
10821172 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples with Implications for Alzheimer’s Disease Risk
Nuestro Sueno:夫妻干预措施的文化适应,以改善拉丁裔夫妇的 PAP 依从性和睡眠健康,对阿尔茨海默病风险产生影响
- 批准号:
10766947 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
CO-LEADER: Intervention to Improve Patient-Provider Communication and Medication Adherence among Patients with Systemic Lupus Erythematosus
共同领导者:改善系统性红斑狼疮患者的医患沟通和药物依从性的干预措施
- 批准号:
10772887 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Pharmacy-led Transitions of Care Intervention to Address System-Level Barriers and Improve Medication Adherence in Socioeconomically Disadvantaged Populations
药房主导的护理干预转型,以解决系统层面的障碍并提高社会经济弱势群体的药物依从性
- 批准号:
10594350 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Antiretroviral therapy adherence and exploratory proteomics in virally suppressed people with HIV and stroke
病毒抑制的艾滋病毒和中风患者的抗逆转录病毒治疗依从性和探索性蛋白质组学
- 批准号:
10748465 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Improving medication adherence and disease control for patients with multimorbidity: the role of price transparency tools
提高多病患者的药物依从性和疾病控制:价格透明度工具的作用
- 批准号:
10591441 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Development and implementation of peer-facilitated decision-making and referral support to increase uptake and adherence to HIV pre-exposure prophylaxis in African Caribbean and Black communities in Ontario
制定和实施同行协助决策和转介支持,以提高非洲加勒比地区和安大略省黑人社区对艾滋病毒暴露前预防的接受和依从性
- 批准号:
491109 - 财政年份:2023
- 资助金额:
$ 323.75万 - 项目类别:
Fellowship Programs