Midwest Biomedical Accelerator Consortium: MBArC

中西部生物医学加速器联盟：MBArC

• 批准号: 9897387
• 负责人: William P Fay
• 金额: $ 99.47万
• 依托单位: UNIVERSITY OF MISSOURI-COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9897387
• 关键词: Active Learning; Address; Award; Awareness; Biological; Biomedical Engineering; Biomedical Research; Biomedical Technology; Businesses; Cities; Clinical; Clinical and Translational Science Awards; Collaborations; Complex; Coupling; Data; Development; Devices; Diagnosis; Economic Development; Entrepreneurship; Evaluation Research; Faculty; Failure; Fostering; Funding; Funding Agency; Geography; Goals; Health; Infrastructure; Institution; Investments; Kansas; Laboratories; Laboratory Research; Leadership; Learning; Legal; Medical; Medical center; Mentors; Mentorship; Methodology; Midwestern United States; Missouri; Modeling; Pathway interactions; Patient Care; Pharmaceutical Preparations; Phase; Population; Postdoctoral Fellow; Process; Public Domains; Research; Research Personnel; Resource Sharing; Resources; Rewards; Risk; Science; Scientist; Societies; Students; System; Talents; Technology; Technology Transfer; Training; Translating; Translational Research; Translations; United States National Institutes of Health; Universities; Work; base; bench to bedside; biological research; biomedical scientist; burden of illness; citizen science; commercialization; frontier; human disease; improved; innovation; inter-institutional; member; method development; novel; novel strategies; prevent; programs; recruit; working group

Project Summary/Abstract The ultimate goal of biomedical research is to create new devices, drugs, and technologies that prevent, diagnose, and treat human diseases. Like scientific discovery, biomedical technology commercialization is complex and requires mentorship, resources, collaboration, and risk. However, several hurdles limit commercialization of promising laboratory discoveries, including 1) lack of awareness by academicians that commercialization is an option, 2) concerns that commercialization efforts delay academic advancement, and 3) failure to connect investigators with the collaborators and experts necessary to complete the commercialization process. The objective of this Research Evaluation and Commercialization Hub (REACH) proposal is to establish a partnership between the University of Missouri-Columbia (MU) and the University of Kansas Medical Center (KUMC) that will promote academic entrepreneurship and commercialization. To this collaboration MU brings its outstanding biomedical and bioengineering research programs and its vibrant track record of participation in the Coulter Translational Research Partnership Award program. KUMC provides its exceptional biomedical research programs and Frontiers, its NIH Clinical and Translational Science Award (CTSA). In addition, each institution has existing partnerships that strengthen and extend the alliance - i.e. 1) MU with University of Missouri state system universities in Kansas City, St. Louis, and Rolla; and 2) KUMC with the Kansas Idea Network of Biomedical Research Excellence (K-INBRE) and the Sustainable Heartland Accelerator Regional Partnership Hub (SHARPhub). The leadership team of this network, entitled the Midwest Biomedical Accelerator Consortium (MBArC), will employ the following strategies to increase biomedical research commercialization: 1) leverage MBArC’s geographic and institutional scope to develop strategic partnerships that invite scientists to engage in technology transfer and commercialization, 2) give academicians the training and resources needed to validate the clinical and commercial feasibility of their innovations, 3) provide researchers with funding and mentorship to complete product definition studies and attract follow- on funding, and 4) offer experiential learning opportunities in biomedical innovation and entrepreneurship. This initiative will build on existing programs in outstanding institutions to increase health-related business development, including small businesses, in Missouri, Kansas, and adjoining states. The MBArC REACH Hub will promote commercialization of novel scientific discoveries and establish a sustainable infrastructure to translate scientific discoveries into commercial products that prevent and treat high-burden diseases afflicting the US population.

项目概要/摘要 生物医学研究的最终目标是创造新的设备、药物和技术 预防、诊断和治疗人类疾病。比如科学发现、生物医学技术 商业化是复杂的，需要指导、资源、协作和风险。 然而，有几个障碍限制了有前途的实验室发现的商业化，包括 1) 院士们缺乏对商业化是一种选择的认识，2) 担心 商业化努力延迟了学术进步，3）未能联系研究人员 与完成商业化过程所需的合作者和专家。这 该研究评估和商业化中心 (REACH) 提案的目标是 密苏里大学哥伦比亚分校 (MU) 与密苏里大学哥伦比亚分校建立合作伙伴关系 堪萨斯医学中心 (KUMC) 将促进学术创业和 商业化。此次合作中，MU 带来了其杰出的生物医学和生物工程 研究项目及其参与库尔特翻译项目的活跃记录 研究合作奖计划。 KUMC 提供卓越的生物医学研究 项目和前沿，其 NIH 临床和转化科学奖 (CTSA)。此外， 每个机构都有现有的合作伙伴关系，可以加强和扩展联盟 - 即 1) MU 与 位于堪萨斯城、圣路易斯和罗拉的密苏里大学州立系统大学； 2) 昆明大学医学中心 与堪萨斯生物医学卓越研究理念网络 (K-INBRE) 和可持续发展 Heartland 加速器区域合作中心 (SHARPhub)。本次领导班子 名为中西部生物医学加速器联盟（MBArC）的网络将采用 以下策略可提高生物医学研究商业化：1) 利用 MBArC 发展战略伙伴关系的地理和机构范围，邀请科学家 从事技术转让和商业化，2）为院士提供培训和 验证其创新的临床和商业可行性所需的资源，3) 提供 研究人员获得资金和指导来完成产品定义研究并吸引追随者 资金，以及 4）提供生物医学创新的体验式学习机会 创业。该举措将建立在优秀机构的现有计划的基础上 促进密苏里州、堪萨斯州与健康相关的企业发展，包括小型企业， 以及毗邻的州。 MBArC REACH 中心将促进新型科学技术的商业化 发现并建立可持续的基础设施，将科学发现转化为 预防和治疗困扰美国人口的高负担疾病的商业产品。