Problem-Solving Therapy for Gulf War Illness

海湾战争疾病的问题解决疗法

• 批准号: 9768224
• 负责人: Lisa Marie McAndrew
• 金额: --
• 依托单位: VA NEW JERSEY HEALTH CARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-01 至 2019-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9768224
• 关键词: Adherence; Advisory Committees; Affect; Behavior; Behavior Therapy; Clinical; Clinical Trials; Cognitive Therapy; Coin; Complex; Conduct Clinical Trials; Disease; Effectiveness; Ensure; Equipment and supply inventories; Exercise; Fatigue; Focus Groups; Functional disorder; Future; Goals; Grant; Gulf War; Health; Health Services Research; Health education; Impairment; Intervention; Interview; Knowledge; Malignant Neoplasms; Manuals; Measures; Medical; Methodology; Methods; Neuropsychology; Neurosciences; Pain; Patient Self-Report; Patients; Perception; Persian Gulf; Population; Problem Solving; Provider; Publishing; Qualitative Methods; Randomized Controlled Trials; Report (document); Research; Research Personnel; Risk; Structure; Suggestion; Symptoms; Testing; Time; Training; Training Support; Treatment Protocols; Veterans; Work; World Health Organization Disability Assessment Schedule; Writing; clinical implementation; cognitive ability; cognitive rehabilitation; design; disability; evidence base; gastrointestinal symptom; improved; innovation; interest; mild traumatic brain injury; multitask; patient oriented; problem solving therapy; programs; prospective; skills; social engagement; success

DESCRIPTION (provided by applicant): The purpose of this CDA is to help Dr. Lisa McAndrew become a national leader in developing and improving patientcenteredself-managementinterventionsforVeteranswithcomplexpost-deployment health concerns. Dr.McAndrewhassignificanttrainingintheoreticalmodelsforunderstandingpatientself-managementand evidence based behavioral treatments. This CDA will allow her to obtain additional skills in (1) health services research, particularly clinical trials and implementation methods (2) qualitative and quantitative methods (3) clinical neuroscience, and (4) grant writing. To support her training goals, Dr. McAndrew will adapt, develop and test a promising cognitive rehabilitation treatment, Problem-Solving Therapy for Gulf War Illness (GWI). Problem-solving is considered one of the most complex of cognitive abilities and is related to complicated behaviors such as setting goals, sequencing and multi-tasking. Impairment in problem-solving ability affects over 70% of Gulf War Veterans (GWV) with GWI and is prospectively related to 1.5 times greater risk of disability. Despite published reports documenting these deficits there are no treatments that target the problem- solving deficits associated with GWI in order to reduce disability. Problem-Solving Therapy teaches patients skills to compensate for problem-solving deficits in order to improve disability, defined as deficits in daily activities and social participation. It has been found to be effective among civilians with mild traumatic brain injury. To modify this intervention, Dr. McAndrew will use qualitative methods to better understand GWVs with GWI as well as VA providers' views on GWI and the proposed problem-solving intervention. She will then use this information to modify Problem-Solving Therapy for use with GWVs with GWI. Finally, she will examine the efficacy of this modified Problem-Solving Therapy for reducing the disability associated with GWI in a pilot randomized controlled trial. Dr.

描述(由申请人提供)： 这项CDA的目的是帮助Lisa McAndrew博士成为发展和改善patientcenteredself-managementinterventionsforVeteranswithcomplexpost-deployment健康问题的全国领导者。 基于Dr.McAndrewhassignificanttrainingintheoreticalmodelsforunderstandingpatientself-managementand证据的行为治疗。这一CDA课程将使她在(1)卫生服务研究，特别是临床试验和实施方法(2)定性和定量方法(3)临床神经科学和(4)拨款撰写方面获得更多技能。为了支持她的训练目标，麦克安德鲁博士将适应、开发和测试一种有前景的认知康复疗法，即海湾战争疾病(GWI)的问题解决疗法。问题解决被认为是最复杂的认知能力之一，与设定目标、排序和多任务等复杂行为有关。超过70%的海湾战争退伍军人(GWV)患有海湾战争退伍军人(GWV)，其解决问题的能力受损，预计与1.5倍的残疾风险有关。尽管发表的报告记录了这些缺陷，但没有针对与GWI相关的问题解决缺陷的治疗方法，以减少残疾。问题解决疗法教授患者弥补问题解决缺陷的技能，以改善残疾，定义为日常活动和社交缺陷 参与。它已被发现对患有轻度创伤性脑损伤的平民有效。为了修改这一干预措施，麦克安德鲁博士将使用定性的方法来更好地理解GWVS与GWI以及退伍军人管理局提供者对GWI和拟议的问题解决干预的看法。然后，她将使用这些信息来修改问题解决疗法，以便与GWVS和GWI一起使用。最后，她将在一项试点随机对照试验中检验这种改进的问题解决疗法在减少与GWI相关的残疾方面的有效性。Dr。