Collaborative Pediatric Critical Care Research Network

儿科重症监护协作研究网络

• 批准号: 9395918
• 负责人: KATHLEEN L. MEERT
• 金额: $ 26.49万
• 依托单位: WAYNE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2019-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9395918
• 关键词: AIDS/HIV problem; Activities of Daily Living; Address; Adolescent Medicine Trials Network; Affect; American; American College of Surgeons; Anabolism; Anxiety; Applied Research; Award; Beds; Behavioral; Behavioral Medicine; Bereavement; Burn Centers; Cardiopulmonary Resuscitation; Caring; Cessation of life; Child; Child Health; Child health care; Childhood; Clinical; Clinical Research; Communication; Communities; Critical Care; Critical Illness; Critically ill children; Development; Doctor of Philosophy; Drug Kinetics; Emergency Care; Family; Fruit; Funding; Goals; Growth and Development function; Health; Healthy People 2020; Heart Arrest; Hemorrhage; Hydrocortisone; Informatics; Information Systems; Injury; Institution; Intervention; Knowledge; Lead; Leadership; Life; Mechanical ventilation; Medical center; Medicine; Methods; Michigan; Mission; National Institute of Child Health and Human Development; Neonatal; Neurological emergencies; Nosocomial Infections; Operative Surgical Procedures; Outcome; Parents; Patients; Pediatric Hospitals; Pediatric Intensive Care Units; Pediatric Oncology Group; Pertussis; Pharmacogenomics; Phenotype; Principal Investigator; Productivity; Public Health; Publications; Research; Research Personnel; Resources; Safety; Schools; Science; Scientist; Sedation procedure; Self Efficacy; Sepsis; Services; Single Nucleotide Polymorphism; Site; Testing; Therapeutic; Transcend; Translational Research; Trust; United States National Institutes of Health; Universities; asthma prevention; clinical research site; cognitive ability; data registry; design; egg; experience; faculty research; follow-up; functional status; health care quality; health disparity; health literacy; health related quality of life; improved; improved outcome; injured children; multidisciplinary; natural hypothermia; novel; operation; opiate tolerance; outcome prediction; patient population; pediatric emergency; pediatric trauma; public health relevance; racial and ethnic; racial and ethnic disparities; racial diversity; research facility; success; tertiary care; trauma centers; treatment trial

 DESCRIPTION (provided by applicant): The Collaborative Pediatric Critical Care Research Network (CPCCRN) is a highly productive research network that is essential to advancing the science and practice of pediatric critical care medicine. The overall aim of this renewal application is for Wayne State University (WSU), under the leadership of Kathleen Meert, MD, to continue as a clinical site in the CPCCRN. Dr. Meert, PI for the CPCCRN at WSU for the past 10 years, is a pediatric intensivist with a wealth of clinical and translational research experienc and an established track record of scientific publications for the CPCCRN. Additionally, Dr. Meert has demonstrated research expertise in behavioral medicine and communication science. Strengths of WSU as a clinical site include the Children s Hospital of Michigan (CHM), a free-standing, tertiary care, academic children s hospital offering the full spectrum of pediatric and surgical subspecialty services. The PICU at CHM is a 38-bed multidisciplinary unit that cares for >1500 patients/year with diverse racial and ethnic backgrounds. Over 85% of PICU patients have follow-up within the institution. CHM is an American College of Surgeons verified Level 1 Pediatric Trauma Center and an American Burn Association verified Burn Center. Additional strengths of WSU include its vast experience with federally-funded multicenter research networks such as the Neonatal Network, Adolescent Medicine Trials Network for HIV/AIDS Intervention, Neurological Emergencies Treatment Trials Network, Pediatric Emergency Care Applied Research Network, and the Children s Oncology Group. The concept proposal included in this application builds on prior CPCCRN research, led by Dr. Meert, demonstrating many challenges to achieving high quality parent-clinician communication in PICUs. High quality communication is especially important for parents with low health literacy, a key contributing factor to child health disparities. Patient- and family-centered communication (PFCC) may improve the quality of communication but depends, in part, on parents active participation (e.g., question asking) during clinical interactions. The objective of the concept proposal is to develop a novel communication intervention, the Question Prompt Toolkit; and determine the extent to which the intervention can enhance PFCC in PICUs, and thus improve child and family outcomes. The central hypothesis is that use of the Question Prompt Toolkit will increase parents active participation in clinical interactions, knowledge, self-efficacy and trust, reduce parent's anxiety, and ultimately contribute to better health-related quality of life for the child and reduced family burden, especially for families with low health literacy. The hypothesis will be tested in multicenter research that pursues 2 specific aims: (1) Develop the Question Prompt Toolkit for use among parents of critically-ill children; and (2) Determine the extent to which the Question Prompt Toolkit can enhance the use of PFCC in PICUs and improve child and family outcomes. The proposal is significant because it will contribute a new communication intervention that can be applied in PICU practice to address parents' communication needs and improve health outcomes.

 描述（由申请人提供）：儿科重症监护协作研究网络 (CPCCRN) 是一个高效的研究网络，对于推​​进儿科重症监护医学的科学和实践至关重要。此次更新申请的总体目标是让韦恩州立大学 (WSU) 在医学博士 Kathleen Meert 的领导下继续作为 CPCCRN 的临床中心。 Meert 博士在过去 10 年中担任 WSU CPCCRN 的 PI，是一名儿科重症监护医师，拥有丰富的临床和转化研究经验，并在 CPCCRN 发表过科学出版物。此外，Meert 博士还展示了行为医学和传播科学方面的研究专业知识。 WSU 作为临床中心的优势包括密歇根儿童医院 (CHM)，这是一家独立的三级护理学术儿童医院，提供全方位的儿科和外科亚专科服务。 CHM 的 PICU 是一个拥有 38 个床位的多学科病房，每年照顾超过 1500 名来自不同种族和民族背景的患者。超过 85% 的 PICU 患者在机构内得到随访。 CHM 是美国外科医生学会认证的 1 级小儿创伤中心和美国烧伤协会认证的烧伤中心。华盛顿州立大学的其他优势包括其在联邦政府资助的多中心研究网络方面拥有丰富的经验，例如新生儿网络、艾滋病毒/艾滋病干预青少年医学试验网络、神经急症治疗试验网络、儿科紧急护理应用研究网络和儿童肿瘤学组。该应用程序中包含的概念提案建立在 Meert 博士领导的先前 CPCCRN 研究的基础上，展示了在 PICU 中实现高质量家长与临床医生沟通的许多挑战。高质量的沟通对于健康素养较低的父母尤其重要，这是造成儿童健康差异的一个关键因素。以患者和家庭为中心的沟通（PFCC）可以提高沟通质量，但部分取决于父母在临床互动过程中的积极参与（例如提问）。该概念提案的目标是开发一种新颖的沟通干预措施，即问题提示工具包；并确定干预措施可以在多大程度上增强 PICU 中的 PFCC，从而改善儿童和家庭的结局。中心假设是，使用问题提示工具包将增加父母对临床互动、知识、自我效能和信任的积极参与，减少父母的焦虑，并最终有助于提高孩子的健康相关生活质量 减轻家庭负担，特别是健康素养较低的家庭。该假设将在多中心研究中得到检验，该研究追求两个具体目标：（1）开发问题提示工具包，供危重儿童的父母使用； (2) 确定在多大程度上 问题提示工具包可以增强 PFCC 在 PICU 中的使用并改善儿童和家庭的结局。该提案意义重大，因为它将提供一种新的沟通干预措施，可应用于儿科重症监护病房（PICU）实践，以满足家长的沟通需求并改善健康结果。