Manipulation of energy metabolism to control lipid accumulation and insulin action.

操纵能量代谢来控制脂质积累和胰岛素作用。

• 批准号: nhmrc : 1003313
• 负责人: Prof Gregory Cooney
• 金额: $ 53.62万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/manipulation-energy-metabolism-insulin-action/108914
• 关键词: Manipulation; energy; metabolism; control; lipid

I am a metabolic biochemist investigating how overconsumption of calories, particularly fat, results in dysfunctional energy metabolism and increased the risk of type 2 diabetes. I examine changes in the daily rhythms of energy intake, energy utilisation and energy storage in different tissues of dietary and genetically modified animals to pinpoint novel ways of reducing fat accumulation and reducing the risk of type 2 diabetes.

我是一名代谢生物化学家，研究过量摄入卡路里，尤其是脂肪，是如何导致能量代谢功能失调，增加患2型糖尿病的风险的。我研究了饮食和转基因动物不同组织中能量摄入、能量利用和能量储存的日常节律变化，以找出减少脂肪积累和降低2型糖尿病风险的新方法。