2020/2022 Alcohol and the Nervous System Gordon Research Conference & Gordon Research Seminar

项目总结/摘要 此R13应用程序请求支持Gordon Research Conference（GRC）和相关的GRS， 酒精和神经系统将于2020年3月和2022年在历史悠久的加尔维斯酒店举行， 德克萨斯州加尔维斯顿。关于这一主题的首届GRC于2014年举行，被认为是一个巨大的成功 所有与会者。这一申请力求在前三次会议成功的基础上， 年轻和成熟的酒精研究人员，以及来自相关领域的杰出科学家，讨论 最新的突破性进展，在神经科学研究酒精相关的健康问题。中央 目标是促进对研究进展的深入和开放的讨论，建立新的科学合作， 并推动下一代酒精神经科学研究的科学进步。以下四 具体目标将确保我们实现这一目标：1）提供一个促进开放的国际论坛， 讨论酒精对神经系统及相关系统影响的前沿前沿研究 神经科学领域。2)介绍突破性的神经科学技术，以促进对 驱动饮酒和滥用酒精的大脑机制，以及涉及胎儿酒精的机制 谱系障碍。3)促进年轻和资深调查人员之间的互动， 这些想法将塑造酒精神经科学界的未来方向。4)促进发展 通过鼓励学生和博士后的参与， 研究员，在酒精和相关研究领域。 酒精和神经系统GRC将专注于在我们的最前沿的演讲和讨论 领域本研究的范围将仅限于涉及酒精的基础和临床研究， 神经系统以及开创性的新神经科学技术， 我们这个领域面临的最大挑战会谈将解决集中在神经基板， 会导致整个生命周期中与酒精相关的健康障碍。独特的GRC格式非常适合 打破进展的障碍，包括正式会谈，其中穿插着充足的讨论时间，海报 会议和非正式讨论期间，旨在促进沟通，规划和协作。 为了培养下一代酒精研究人员，我们将共同努力， 鼓励和支持学生，博士后研究员和年轻的研究人员参与，无论是在 GRC和GRS。因此，R13将促进前沿酒精研究的交流， 边缘科学合作，以及新的和年轻的研究人员进入酒精研究领域。我们 我认为，关于酒精和神经系统的GRC和相关的GRS将大大促进我们的 目前对酒精成瘾的神经生物学的理解，并刺激有效的发展 用于治疗酒精使用障碍的治疗方法。

Project Summary/Abstract This R13 application requests support for the Gordon Research Conference (GRC) and associated GRS on Alcohol and the Nervous System that will take place in March 2020 and 2022 at the historic Hotel Galvez in Galveston, TX. The inaugural GRC on this topic took place in 2014 and was considered a tremendous success by all attendees. This application seeks to build on the success of the first three meetings by bringing together young and established alcohol researchers, as well as preeminent scientists from related fields, to discuss the latest groundbreaking developments in neuroscience research on alcohol-related health issues. The central goal will be to foster deep and open discussion of research developments, build new scientific collaborations, and propel the next generation of scientific advances in alcohol neuroscience research. The following four specific aims will ensure that we accomplish this goal: 1) To provide an international forum that promotes open discussion of cutting-edge research at the forefront of alcohol effects on the nervous system and related neuroscience areas. 2) To introduce breakthrough neuroscience techniques that facilitate the understanding of brain mechanisms driving alcohol drinking and abuse, as well as mechanisms involved in fetal alcohol spectrum disorders. 3) To promote interaction between young and senior investigators and the exchange of ideas that will shape the future directions of the alcohol neuroscience community. 4) To foster the development of the next generation of alcohol researchers by encouraging the participation of students and postdoctoral fellows, both in alcohol and related research fields. The Alcohol and the Nervous System GRC will focus on presentations and discussions at the forefront of our field. The scope of the research presented will be restricted to basic and clinical studies involving alcohol and the nervous system as well as groundbreaking new neuroscience techniques that can be brought to bear on the greatest challenges facing our field. Talks will address questions centered on the neural substrates that contribute to alcohol-related health disorders across the entire lifespan. The unique GRC format is ideal for breaking down barriers to progress and includes formal talks interspersed with ample discussion time, poster sessions, and informal discussion periods designed to stimulate communication, planning, and collaboration. To foster the growth of the next generation of alcohol researchers, we will put concerted efforts into encouraging and supporting participation of students, postdoctoral fellows and young investigators, both in the GRC and GRS. Thus, this R13 will foster communication of frontier alcohol research, opportunities for cutting edge scientific collaboration, and entry of new and younger investigators into the alcohol research field. We envision the GRC and associated GRS on Alcohol and the Nervous System will significantly advance our current understanding of the neurobiology of alcohol addiction and stimulate the development of effective therapeutic approaches for the treatment of alcohol use disorders.