TRAINING IN NEUROTHERAPUETICS AND DEVELOPMENT FOR ACADEMIC SCIENTISTS
学术科学家的神经治疗学和发展培训
基本信息
- 批准号:9910467
- 负责人:
- 金额:$ 26.49万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-05-15 至 2022-02-28
- 项目状态:已结题
- 来源:
- 关键词:ADME StudyAcademiaAddressAreaBiologic DevelopmentBiological AssayBiological MarkersBiological Response Modifier TherapyBrainBrain DiseasesCell TherapyCritiquesDevelopmentDevelopment PlansEducational CurriculumElementsFacultyFormulationFundingFutureGene ProteinsGoalsGovernmentGrantIndividualIndustryIntellectual PropertyKnowledgeLeadLearningLogisticsMedicineMentorsMentorshipMonitorParticipantPharmaceutical ChemistryPostdoctoral FellowProcessQuality of lifeResearchResearch PersonnelResourcesScientistSeriesSpecialistStructureStudentsTeacher Professional DevelopmentTimeTrainingTraining ProgramsUnited States National Institutes of HealthVisionWorkanimal efficacyapprenticeshipbasedesigndisabilitydrug developmentdrug discoveryefficacy testingexperienceimprovedinstructorinterestlecturerlecturesmembernervous system disorderrecruitresponsible research conductsafety testingskillssmall moleculesocial mediasuccessteacher
项目摘要
Project Summary/Abstract
This project will develop and implement a training program in neurotherapeutics discovery and
development for faculty members and advanced postdoctoral fellows, centered around a 3½-day short course
that will provide the trainees with the various knowledge elements required to discover and advance a
neurotherapeutic agent to IND. Following the short course, the training program will continue for a two-year
period in which students will have individualized mentoring and assessment. The training, which is designed
to be applicable to diverse diseases of the nervous system, will equip students with a broad understanding
of the various component steps in the neurotherapeutics drug discovery and development process.
Students will learn how to identify a good drug discovery target; how to construct an assay; the elements of
medicinal chemistry; how to conduct animal efficacy testing; the principles of ADME studies, safety testing,
and formulation; the principles of experimental medicine and biomarkers; the steps required to prepare an
IND document and the principles for interacting with the FDA; the principles of intellectual property as they
relate to neurotherapeutics discovery and development; and how to seek funding for academic drug
discovery research. They will also receive training in responsible conduct of research. Students will be
equipped with the skills to develop and coordinate an entire drug discovery and development effort, and to
work collaboratively with experts in each of the component areas. The training will combine didactic lectures
with active engagement activities in which the students will be challenged to utilize the lecture material to work
through their own drug discovery project plan with the guidance of the area experts. The 3½-day short course
(followed by two-years of mentorship and assessment) will be offered annually, a total of five times.
项目摘要/摘要
该项目将开发和实施一个神经疗法发现和培训计划
教师和高级博士后研究员的发展,以3.5天的短期课程为中心
这将为学员提供所需的各种知识元素,以发现和提高
IND的神经治疗剂。短期课程结束后,培训计划将持续两年
学生将接受个性化指导和评估的时期。培训,这是专门设计的
适用于各种神经系统疾病,将使学生对此有广泛的认识。
神经疗法药物发现和开发过程中的各个组成部分步骤。
学生将学习如何确定一个好的药物发现目标;如何构建一种分析方法;
药物化学;如何进行动物药效试验;ADME研究的原则,安全性试验,
和配方;实验医学和生物标记物的原理;制备
IND文件和与FDA互动的原则;知识产权原则
与神经治疗学的发现和发展有关;以及如何为学术药物寻求资金
发现性研究。他们还将接受负责任地进行研究的培训。学生们将成为
具备开发和协调整个药物发现和开发工作的技能,并
与每个组件领域的专家协作。培训将结合说教讲座。
通过积极参与的活动,学生将被要求利用讲课材料进行工作
通过自己的药物发现项目计划,在地区专家的指导下完成。为期3天半的短期课程
(随后为期两年的指导和评估)将每年提供,总共五次。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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MICHAEL A. ROGAWSKI其他文献
MICHAEL A. ROGAWSKI的其他文献
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{{ truncateString('MICHAEL A. ROGAWSKI', 18)}}的其他基金
Training in Neurotherapeutics for Academic Scientists
学术科学家神经治疗学培训
- 批准号:
10666685 - 财政年份:2022
- 资助金额:
$ 26.49万 - 项目类别:
Training in Neurotherapeutics for Academic Scientists
学术科学家神经治疗学培训
- 批准号:
10539175 - 财政年份:2022
- 资助金额:
$ 26.49万 - 项目类别:
Identification of Treatments for Chemical Threat Agent Seizures
查获化学威胁剂的治疗方法的确定
- 批准号:
10204124 - 财政年份:2012
- 资助金额:
$ 26.49万 - 项目类别:
Identification of treatments for chemical threat agent seizures
确定化学威胁剂缉获的治疗方法
- 批准号:
8851849 - 财政年份:
- 资助金额:
$ 26.49万 - 项目类别:
Ion Channels in Epilepsy and as Targets for Antiepilepti
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ION CHANNELS IN EPILEPSY AND AS TARGETS FOR ANTIEPILEPTIC DRUGS
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6290637 - 财政年份:
- 资助金额:
$ 26.49万 - 项目类别:
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