2020 Biology of Spirochetes GRC/GRS

2020年螺旋体生物学GRC/GRS

• 批准号: 9912527
• 负责人: D. SCOTT SAMUELS
• 金额: $ 1.1万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-02-12 至 2023-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9912527
• 关键词: Acute; Address; Animal Model; Animals; Bacteria; Basic Science; Biology; Collaborations; Diagnostic; Discipline; Disease; Distant; Ecology; Emerging Communicable Diseases; Environment; Epidemiology; Equilibrium; Etiology; Evolution; Face; Faculty; Flagella; Fostering; Foundations; Genomics; Growth; Health; Hour; Human; Immune Evasion; Infection; International; Intestines; Leptospirosis; Life; Life Style; Lyme Disease; Mainstreaming; Microbiology; Mission; Modeling; Oral; Order Spirochaetales; Outcome; Participant; Pathogenesis; Pathogenicity; Periodontal Diseases; Phylogenetic Analysis; Physiology; Postdoctoral Fellow; Prevention strategy; Relapsing Fever; Research; Research Personnel; Running; Science; Scientist; Shapes; Spirochaetales Infections; Stress; Structure; Syphilis; Taxonomy; Time; Training; Underrepresented Groups; Underrepresented Minority; Virulence Factors; Woman; Work; Zoonoses; career; career development; design; frontier; genetic approach; graduate student; human disease; improved; interest; kindred; meetings; microorganism; pathogen; pathogenic bacteria; periplasm; posters; programs; structural biology; symposium; treatment strategy; vector-borne

Abstract The Spirochetes are a deeply-branching phylum of bacteria initially delineated by their serpentine shape and periplasmic flagella. Pathogenic spirochetes are the etiologic agents of many globally significant emerging and re-emerging infectious diseases, including Lyme disease, syphilis, leptospirosis, relapsing fever, and intestinal spirochetosis. In addition, they participate in polymicrobial infections and host-bacterial endosymbioses, and they are models for vector-borne, environmental, and zoonotic infections. The Biology of Spirochetes Gordon Research Conference (BoS GRC) and the accompanying Gordon Research Seminar (BoS GRS), which is organized by and targeted to researchers in training, have been held every two years since 1994 and serve as the only scientific meetings that bring together researchers who work on this structurally and taxonomically unique phylum of bacteria. The 2020 BoS GRC and GRS programs have been designed to highlight the diversity of research in spirochete biology and disease pathogenesis. Our first Aim is to promote presentation and discussion of diverse and cutting-edge research on spirochete disease pathogenesis and spirochete biology, including host interactions and defenses, immune evasion and persistence mechanisms, ecology and evolution, and structural biology and physiology. Our second Aim is to promote career development for all scientists studying spirochetes. To achieve these Aims, we have invited 36 speakers to the 2020 BoS GRC, many of whom are first-time attendees including three trainees. We have reserved eight speaking slots for “poster talks” that will be selected from the abstracts submitted by attendees for poster presentations. The BoS GRS will include oral presentations, poster presentations, and panel discussions focused on career options in science. The BoS GRC will include a “Power Hour”, an informal gathering for all meeting participants to address the challenges women face in science and to support the professional growth of women in science. Both the GRC and the GRS programs reflect the diversity of the research and the scientists in the field, with strong representation of women and international scientists as both speakers and discussion leaders. The vast majority of the major advances in spirochete research during the past 20 years evolved from the discussions and collaborations fostered by the BoS GRC: the 2020 conferences endeavor to continue this laudable trajectory.

抽象的 螺旋体是最初由蛇形形状和 周质鞭毛。致病性螺旋体是许多全球意义上出现和 重新出现的传染病，包括莱姆病，梅毒，钩端螺旋体病，发烧复发和肠道 螺旋病。此外，他们还参与多数菌感染和宿主 - 细菌内共生体，以及 它们是媒介传播，环境和人畜共患感染的模型。 Spirochetes Gordon的生物学 研究会议（BOS GRC）和参与的戈登研究研讨会（BOS GRS）， 自1994年以来，由培训研究人员组织和针对培训的研究人员每两年举行一次 唯一将研究人员从结构和分类学上进行研究的研究人员聚集在一起的唯一科学会议 独特的细菌门。 2020年BOS GRC和GRS程序的设计旨在突出显示 螺旋体生物学和疾病发病机理研究的多样性。我们的第一个目的是促进演讲 并讨论有关螺旋病疾病发病机理和螺旋体的多样化和尖端研究 生物学，包括宿主的互动和防御，免疫进化和持久机制，生态学和 进化以及结构生物学和生理学。我们的第二个目标是促进所有人的职业发展 研究螺旋体的科学家。为了实现这些目标，我们邀请了36位发言人到2020年BOS GRC， 其中许多是首次参加者，包括三个培训。我们保留了八个口语插槽 将从与会者提交的海报演示的摘要中选择的“海报谈话”。 BOS GRS将包括口头演讲，海报演示和小组讨论，重点是职业选择 科学。 BOS GRC将包括一个“电力时光”，这是一个非正式聚会，为所有会议参与者提供 应对妇女在科学领域面临的挑战，并支持科学妇女的专业成长。 GRC和GRS计划都反映了研究的多样性以及该领域的科学家， 妇女和国际科学家的强烈代表是演讲者和讨论领袖。差距 在过去20年中，大多数螺旋体研究的主要进步是从讨论中演变而来的 以及由BOS GRC培养的合作：2020年会议努力继续这一值得称赞 弹道。