ACUTE RADIATION-INDUCED LUNG INJURY IN THE RHESUS MACAQUE AND ITS' TREATMENT BYIPW-5371, A SMALL MOLECULE INHIBITOR OF TGF# RECEPTOR-1 KINASE
ACUTE RADIATION-INDUCED LUNG INJURY IN THE RHESUS MACAQUE AND ITS' TREATMENT BYIPW-5371, A SMALL MOLECULE INHIBITOR OF TGF# RECEPTOR-1 KINASE
恒河猴急性辐射肺损伤及其TGF-β小分子抑制剂YIPW-5371的治疗
批准号：
9915646
负责人：
BARRY HART
金额：
$231.56万
依托单位：
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
项目状态：
已结题
起止时间：
2019-04-01 至 2020-03-31
关键词：
AcuteDevelopmentDoseDrug KineticsEvaluationExposure toInjuryIonizing radiationMacaca mulattaModelingMorbidity - disease rateNuclear AccidentsPharmaceutical PreparationsPhosphotransferasesRadiationRadiation AccidentsRespiratory physiologyScheduleSupport ContractsTissuesTransforming Growth Factor betaWorkdrug synthesisefficacy studyimprovedkinase inhibitorlung injurymortalityreceptorscale upsmall moleculesmall molecule inhibitor
中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
1. This contract supports the development of safe and effective MCMs to mitigate and/or treat tissue injuries arising from exposure to ionizing radiation from a radiological or nuclear incident, thereby leading to a reduction in radiation-associated morbidities and mortalities.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
THE PHARMACOLOGICAL DEVELOPMENT OF IPW-5371 FUMARATE AS A RADIATION MEDICAL COUNTERMEASURE FOR THE TREATMENT OF DELAYED RADIATION LUNG INJURY UNDER THE FDA ANIMAL RULE
-
批准号：10932585
-
项目类别：
-
资助金额：$149.99万
-
财政年份：2023
-
负责人：BARRY HART
-
依托单位：
ACUTE RADIATION-INDUCED LUNG INJURY IN THE RHESUS MACAQUE AND ITS' TREATMENT BYIPW-5371, A SMALL MOLECULE INHIBITOR OF TGF# RECEPTOR-1 KINASE
-
批准号：10661478
-
项目类别：
-
资助金额：$11.38万
-
财政年份：2020
-
负责人：BARRY HART
-
依托单位：
国内基金
海外基金
水稻边界发育缺陷突变体abnormal boundary development(abd)的基因克隆与功能分析
-
批准号：32070202
-
项目类别：面上项目
-
资助金额：58.0万元
-
批准年份：2020
-
负责人：汪泉
-
依托单位：
Development of a Linear Stochastic Model for Wind Field Reconstruction from Limited Measurement Data
-
批准号：--
-
项目类别：--
-
资助金额：40万元
-
批准年份：2020
-
负责人：Vikrant Gupta
-
依托单位：
