SETAC North America Non-Target Analysis in Environmental Risk Assessment Focus Topic Meeting

SETAC北美环境风险评估非目标分析焦点专题会议

• 批准号: 9914759
• 负责人: Tamar Schlekat
• 金额: $ 1.5万
• 依托单位: SOCIETY/ENVIRON/ TOXICOLOGY/CHEMISTRY NA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-05 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9914759
• 关键词: Academia; Address; Analytical Chemistry; Applications Grants; Archives; Area; Benchmarking; Biological; Chemicals; Data; Data Analyses; Data Science; Development; Discipline; Ecosystem; Engineering; Environmental Monitoring; Environmental Pollution; Environmental Risk Factor; Evaluation; Fees; Funding; Goals; Government; Health; Home environment; Human; Image; Industry; International; Journals; Knowledge; Modeling; Monitor; National Institute of Environmental Health Sciences; Nonprofit Organizations; North America; North Carolina; Occupations; Outcome; Output; Peer Review; Performance; Private Sector; Publications; Recording of previous events; Regulation; Reporting; Reproducibility; Research; Risk Assessment; Safety; Sampling; Science; Scientist; Series; Slide; Societies; Structure; Superfund; Toxic effect; Toxicology; Travel; Vision; anthropogenesis; cheminformatics; cost; data archive; data tools; environmental chemistry; environmental stressor; environmental toxicology; experimental study; instrumentation; journal article; medical specialties; meetings; posters; programs; statistics; symposium; tool

SETAC North America Focused Topic Meeting Non-Targeted Analysis for Comprehensive Environmental Assessment Durham Convention Center, Durham, North Carolina, USA May 26-31, 2020 Project Summary NIEHS support is sought for the SETAC North America Focused Topic Meeting “Non-Targeted Analysis for Comprehensive Environmental Assessment.” The meeting priority is to advance sub-disciplines involved in high-throughput identification, scientific study, and regulation of chemicals in environmental and biological media relevant to human and ecosystem health. The meeting will gather experts to report on recent advances in the field and identify significant research needs hindering the wide-spread implementation and use of non-targeted analysis results. To meet the proposed meeting’s objectives, we will pursue the following specific goals: 1. Provide a forum for professionals from different disciplines (including data science and statistics, (eco-)toxicology, analytical and environmental chemistry, cheminformatics, exposure, toxicity, and risk assessment) and from many backgrounds (academia, industry, government, and non-profit organizations) to come together to discuss and advance the state of the knowledge in the field; 2. Develop a framework for compound identification prioritization in non-targeted analysis of environmental and biological samples; 3. Propose benchmarks for analytical and data analyses, performance, and publication; 4. Identify knowledge gaps and shortcomings related to the reproducible acquisition, reporting and archiving of data generated by non-targeted analysis experiments; 5. Critically assess strengths and practical limitations of using non-targeted analysis in environmental monitoring, exposomics research, and chemical risk assessment. These goals will be achieved by convening leading international experts diverse research fields, job activities, and organizations. Funds being sought through this grant application will be used to offset the cost of the attendance for 12 invited experts and to include registration fees and a travel stipend. The meeting will span five days consisting of a combination of platform and poster sessions, breakout groups, panel discussions, and tool demonstrations, and is expected to attract 200 experts. The meeting technical program will cover four main topics: 1. State of the science in non-targeted analysis: instrumentation, data evaluation, monitoring application 2. Prioritizing unknowns for identification: new analytes, transformation products and metabolites 3. Tools for data analysis and beyond: statistics, exposure, toxicity, modeling 4. Looking ahead: benchmarks, knowledge gaps, and wide-spread implementation Meeting outcomes include at least one peer-reviewed journal article to summarize the state-of- the-science and capture discussions and ideas. We also expect to develop a journal article series on the topic from submissions by presenters. Further, poster and slide images from meeting presentation will be archived.

塞塔克北美以塞塔克为中心的主题会议 针对全面环境评估的非目标分析 达勒姆会议中心，美国北卡罗来纳州达勒姆市 5月26日至31日，2020年 项目摘要 NIEHS的支持是在Setac北美的主题上感受到的“非目标 分析全面的环境评估。 涉及高通量识别，科学研究和调节的子学科 环境和生物媒体中与人类和生态系统健康有关的化学物质。 会议将收集专家报告该领域的最新进展并确定重要的 研究需要阻碍广泛的实施和使用非目标分析 结果。 为了实现拟议的会议的目标，我们将实现以下具体目标： 1。为来自不同学科的专业人员提供论坛（包括数据科学和 统计学，（生态）毒理学，分析和环境化学，化学信息学， 暴露，毒性和风险评估）和许多背景（学术界， 行业，政府和非营利组织）聚集在一起讨论和 促进该领域的知识状态； 2。在非目标分析中开发一个复合识别优先级的框架 环境和生物样品； 3。提出用于分析和数据分析，绩效和出版物的基准； 4.确定与可重复获取有关的知识差距和缺点， 通过非目标分析实验生成的数据报告和归档； 5。批判性地评估使用非目标分析的优势和实际局限性 环境监测，外汇研究和化学风险评估。 这些目标将通过召集领先的国际专家潜水员研究领域来实现， 工作活动和组织。通过此赠款申请感知资金 以抵消12位受邀专家的出席费用，并包括注册费和 旅行压力。会议将跨越五天，包括平台和 海报会议，突破组，小组讨论和工具演示，可以预期 吸引200名专家。 会议技术计划将涵盖四个主要主题： 1。非目标分析中的科学状态：仪器，数据评估，监视 应用 2。确定未知数的优先级：新的分析物，转换产品和 代谢物 3。数据分析及其他的工具：统计，暴露，毒性，建模 4。展望未来：基准，知识差距和广泛实施 满足成果包括至少一份同行评审的期刊文章，以总结最新 科学并捕捉讨论和思想。我们还希望开发一篇期刊文章 主持人提交的主题系列。此外，来自 会议演讲将被存档。