Resonance and Aeroacoustic Relationship in Velopharyngeal Insufficiency

 描述(由申请者提供)：K25量化研究职业发展奖的目标是使候选人能够在语音声学和空气声学领域发展专业知识，该研究计划旨在调查影响腭咽闭合不全(VPI)语音障碍的声源机制。专业发展计划包括在指导和咨询团队的监督下，由课程作业、研讨会、研讨会和个人学习组成的结构化课程。指导委员会包括由多学科研究人员组成的团队，他们在言语和言语障碍的声学建模、言语的空气动力学、空气声学、医学成像技术和VPI的临床管理方面具有专业知识。该研究计划涉及特定的目标，旨在解决由于腭咽闭合开口的大小与VPI和语音失真的严重程度之间缺乏相关性而存在的知识差距。这项研究将以两个假设为指导：1)气流引起的声音特征会随着腭咽开口大小的增加而减少；2)共振引起的声音特征会随着腭咽开口大小的增加而增加。该奖项提供的培训和研究经验将使候选人能够成功地担任VPI和颅面畸形临床领域的独立研究员。

 DESCRIPTION (provided by applicant): The goal of this K25 Mentored Quantitative Research Career Development Award is to enable the candidate to develop expertise in the areas of acoustics and aeroacoustics of speech, in the context of a research plan that investigates sound source mechanisms that affect speech disorders due to velopharyngeal insufficiency (VPI). The professional development plan involves a structured curriculum of coursework, workshops, seminars, and individual study under the supervision of a mentorship and advisory team. The mentorship committee includes multidisciplinary team of established researchers with expertise in acoustic modeling of speech and speech disorders, aerodynamics of speech, aeroacoustics, medical imaging techniques, and clinical management of VPI. The research plan involves specific aims that have been designed to address the gap in knowledge for the lack of correlation between the size of the velopharyngeal opening with VPI and the severity of speech distortion. The research will be guided by two hypotheses: 1) sound characteristics due to airflow will decrease as the size of the velopharyngeal opening is increased; 2) sound characteristics due to resonance will increase as the size of the velopharyngeal opening is increased. The training and research experience provided by this award will enable the candidate to successfully bear as an independent researcher in the clinical areas of VPI and craniofacial anomalies.