Asthma and Allergic Diseases Group

哮喘和过敏性疾病组

• 批准号: 9927585
• 负责人: Samuel Arbes
• 金额: $ 424.67万
• 依托单位: RHO FEDERAL SYSTEMS DIVISION, INC.
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9927585
• 关键词: Achievement; Allergic Disease; Area; Asthma; Atopic Dermatitis; Autoimmune Diseases; Biological; Biological Specimen Banks; Clinical; Clinical Investigator; Collaborations; Collection; Communication; Data Collection; Data Reporting; Development; Disease; Ethics; Food Hypersensitivity; Funding; Funding Opportunities; Human Resources; Hypersensitivity; Immune Tolerance; Immunization; Immunology; Infrastructure; Label; Monitor; National Institute of Allergy and Infectious Disease; Online Systems; Preparation; Procedures; Process; Protocols documentation; Publications; Quality Control; Registries; Reporting; Research; Resources; Sampling; Scientist; Services; Shipping; Standardization; Statistical Data Interpretation; Structure; System; Technology; Training; Transplantation; U-Series Cooperative Agreements; Update; Vaccinia; Writing; clinical research site; cost; design; experience; inner city; instrument; meetings; member; operation; prevent; programs; protocol development; repository; rho; success

PROJECT SUMMARY/ABSTRACT—ASTHMA AND ALLERGIC DISEASES GROUP Through this Funding Opportunity Announcement, the NIAID Division of Allergy, Immunology and Transplantation (DAIT) intends to consolidate its funding for multiple, independent Statistical and Clinical Coordinating Centers (SACCCs) into a single multi-component cooperative agreement, presumably to reduce costs and increase efficiency and standardization across research consortia. This new program will fund a single SACCC or Center to support DAIT research in the areas of asthma and allergic diseases, autoimmune diseases, and transplantation, and in the area of asthma and allergic diseases research, this Center will provide support to 5 consortia—the Asthma and Allergic Diseases Cooperative Research Centers (AADCRCs), the Atopic Dermatitis Research Network (ADRN), the Consortium of Food Allergy Research (CoFAR), the Inner-City Asthma Consortium (ICAC), and the asthma and allergy component of Immune Tolerance Network (ITN). Within the Center, support for these 5 consortia will be organized under 1 group—the Asthma and Allergy Diseases Group (AADG). The objective of the AADG is to provide excellent and efficient study coordination support services across the 5 asthma and allergic diseases research consortia. To accomplish this objective, RhoFED aims to (1) provide staff experienced in asthma and allergic disease research conducted by DAIT-supported consortia and to organize these staff in an administrative structure that manages resources efficiently, is responsive to the needs of the research consortia and DAIT, and facilitates communication and collaboration; (2) provide experienced scientists and statisticians who, in collaboration with clinical investigators and senior DAIT officials, design and analyze studies across the full scope of research in asthma and allergic diseases; (3) facilitate the development, review, and revision of initial and successive drafts of protocols and protocol-related documents through dedicated AADG protocol teams; and (4) provide study initiation and study management functions that are required for the efficient, valid, and ethical conduct of studies. In addition, the AADG will support the continuation of the ADRN Subject Registry and the ICAC Clinical Specimen Repository. Because RhoFED is currently the SACCC for ADRN, ICAC, and ITN and maintains the ADRN Subject Registry and the ICAC Clinical Specimen Repository, RhoFED is well suited to provide consolidated SACCC support across the 5 consortia. And, by providing staff with experience in supporting asthma and allergic disease research consortia and an administrative infrastructure designed to enhance collaboration between parties and support agile and effective resource management, we believe that support of these 5 consortia through the newly formed Center and the AADG will directly contribute to the achievement of the DAIT objective to better understand, treat, and prevent asthma and allergic diseases.

项目概要/摘要——哮喘和过敏性疾病组 通过本次资助机会公告，NIAID 过敏、免疫学和 移植 (DAIT) 打算整合其对多个独立统计和临床项目的资助 将协调中心 (SACCC) 纳入单一的多组成部分合作协议，大概是为了减少 成本并提高研究联盟的效率和标准化。这项新计划将资助 单一 SACCC 或中心支持 DAIT 在哮喘和过敏性疾病、自身免疫性疾病领域的研究 疾病、移植、哮喘和过敏性疾病研究领域，该中心将 为 5 个联盟提供支持——哮喘和过敏性疾病合作研究中心 (AADCRC)、 特应性皮炎研究网络 (ADRN)、食物过敏研究联盟 (CoFAR)、 内城哮喘联盟 (ICAC) 以及免疫耐受网络的哮喘和过敏部分 （ITN）。在该中心内，对这 5 个联盟的支持将由 1 个小组组织——哮喘和 过敏性疾病组 (AADG)。 AADG 的目标是提供优秀且高效的学习 跨 5 个哮喘和过敏性疾病研究联盟的协调支持服务。为了完成 为了实现这一目标，RhoFED 旨在 (1) 提供在哮喘和过敏性疾病研究方面经验丰富的工作人员 由 DAIT 支持的财团进行，并将这些工作人员组织到一个管理结构中 有效地利用资源，响应研究联盟和 DAIT 的需求，并促进 沟通与协作； (2) 提供经验丰富的科学家和统计学家，他们与 临床研究人员和 DAIT 高级官员设计和分析整个研究范围的研究 哮喘和过敏性疾病； (3) 促进初始和后续的制定、审查和修订 通过专门的 AADG 协议团队起草协议和协议相关文件的草案； (4) 提供 高效、有效和合乎道德的行为所需的研究启动和研究管理职能 研究。此外，AADG 将支持 ADRN 主题注册表和 ICAC 的延续 临床样本库。因为 RhoFED 目前是 ADRN、ICAC 和 ITN 的 SACCC，并且 RhoFED 维护着 ADRN 受试者登记处和 ICAC 临床样本存储库，非常适合 为 5 个联盟提供统一的 SACCC 支持。并且，通过为员工提供以下方面的经验 支持哮喘和过敏性疾病研究联盟以及旨在 加强各方之间的协作并支持敏捷有效的资源管理，我们认为 通过新成立的中心和 AADG 对这 5 个联盟的支持将直接为 实现 DAIT 目标，即更好地了解、治疗和预防哮喘和过敏性疾病。