Rehabilitation at home using mobile health in older adults after hospitalization for ischemic heart disease (RESILIENT)
使用移动医疗对因缺血性心脏病住院的老年人进行家庭康复(RESILIENT)
基本信息
- 批准号:9973123
- 负责人:
- 金额:$ 66.04万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-07-15 至 2024-04-30
- 项目状态:已结题
- 来源:
- 关键词:Academic Medical CentersActivities of Daily LivingAcute myocardial infarctionAerobicAgeBehavioral SciencesBiometryBlindedCardiac rehabilitationCardiologyCardiovascular systemCessation of lifeClinical ResearchComputer softwareControl GroupsCoronary Artery BypassCounselingDataDiseaseDocumentationEducationElderlyElectronic MailElectronicsEnrollmentEthnic OriginExerciseFaceFoundationsGeneral PopulationGeriatricsGoalsGuidelinesHealthHealth StatusHeart BlockHome environmentHospitalizationImpaired cognitionImpairmentInterventionLeadMeasuresModificationMulti-Institutional Clinical TrialMyocardial IschemiaOutcomeOutcomes ResearchParticipantPatientsPatternPersonsPhysical FunctionPhysical MedicinePopulationProliferatingRaceRandomizedRandomized Clinical TrialsRehabilitation therapyResearch PersonnelResourcesRisk FactorsSocial supportSupervisionTablet ComputerTechnologyTelephoneTestingTimeTransportationWait TimeWalkingbehavioral clinical trialcomorbiditycomputer sciencecostdepressive symptomsexperiencefrailtyhemodynamicshigh riskhospital readmissionimprovedimproved functioninginstrumental activity of daily livingmHealthmedical schoolsmultidisciplinaryolder patientpatient populationpercutaneous coronary interventionportabilitypreservationprimary endpointprogramsprospectiverandomized effectiveness trialreadmission ratesrecruitrehabilitation paradigmrehabilitation sciencerehabilitation strategyresearch studysextreatment as usual
项目摘要
Project Summary
Participation in ambulatory cardiac rehabilitation (CR) by patients with ischemic heart disease (IHD) remains
low. By recent estimates, fewer than two thirds of eligible patients are referred, and fewer than half of those
referred participate. Even among those referred, multiple barriers to participation include limited facilities,
competing time demands, high out-of-pocket costs, and prolonged wait time. Barriers to CR are particularly
high in older adults (age ≥70), due to factors such as physical impairments or transportation barriers, although
these patients may simultaneously have the greatest potential to benefit. Mobile health-enabled CR (mHealth-
CR) for IHD – which involves delivery of CR via portable electronic devices – has the potential to increase
engagement by reducing participation barriers, but it remains largely untested outside of small studies in
relatively healthy young persons. It is therefore unclear what proportion of older adults with IHD and barriers to
traditional CR are able to engage with mHealth-CR, and whether mHealth-CR leads to better outcomes than
usual care. Therefore, we propose RESILIENT: Rehabilitation at home using mobile health in older adults
after hospitalization for ischemic heart disease. This is a prospective, multicenter, non-blinded randomized
clinical trial (with blinded assessment of primary endpoint) to evaluate engagement and outcomes with
mHealth-CR among older adults with IHD, identified at the time of acute myocardial infarction (AMI),
percutaneous coronary intervention (PCI), or coronary artery bypass graft (CABG). The trial will be conducted
at two academic medical centers: NYU School of Medicine and Yale School of Medicine, which collectively
serve a diverse patient population and have a track record of successfully recruiting older adults in clinical
research studies. We will randomize 400 older adults with IHD to receive mHealth-CR (n=300) or usual care
(n=100) for 3 months. Our intervention combines mHealth-CR software, delivered via a tablet device, with
baseline counseling and weekly phone calls by an exercise therapist over 3 months. Intervention and usual
care groups will also receive a standard referral to ambulatory CR in accordance with guidelines, as well as
dynamic assessment of activities of daily living (ADLs). The primary efficacy endpoint is change in functional
capacity, assessed by 6 minute walk distance. Secondary efficacy endpoints are goal attainment, health
status, ADLs, hospital readmission, and death. The engagement endpoint is defined by weekly completion of
mHealth-CR tasks. We hypothesize that mHealth-CR will improve a range of outcomes, and that distinct
patterns of engagement will be discerned. The PI for this project (Dr. Dodson) is an Early Stage Investigator
with a focus on cardiovascular outcomes research among older adults; additional investigators have a wide
range of expertise in geriatrics, biostatistics, behavioral science, cardiac rehabilitation, and computer science.
The study results could lead to new sustainable and resource-efficient CR strategies among older adults with
IHD, and lay the groundwork for a subsequent large multi-center clinical trial.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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John A Dodson其他文献
John A Dodson的其他文献
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{{ truncateString('John A Dodson', 18)}}的其他基金
Midcareer award in aging-related subspecialty research
与衰老相关的专业研究中的职业生涯中期奖
- 批准号:
10570687 - 财政年份:2023
- 资助金额:
$ 66.04万 - 项目类别:
COVID-19 shutdown: impact of healthcare disruptions on cardiovascular health disparities among people with multiple chronic conditions in New York City.
COVID-19 关闭:医疗保健中断对纽约市多种慢性病患者心血管健康差异的影响。
- 批准号:
10707047 - 财政年份:2022
- 资助金额:
$ 66.04万 - 项目类别:
COVID-19 shutdown: impact of healthcare disruptions on cardiovascular health disparities among people with multiple chronic conditions in New York City.
COVID-19 关闭:医疗保健中断对纽约市多种慢性病患者心血管健康差异的影响。
- 批准号:
10436056 - 财政年份:2022
- 资助金额:
$ 66.04万 - 项目类别:
BETTER-BP (Behavioral Economics Trial To Enhance Regulation of Blood Pressure)
BETTER-BP(加强血压调节的行为经济学试验)
- 批准号:
10227750 - 财政年份:2019
- 资助金额:
$ 66.04万 - 项目类别:
Rehabilitation at home using mobile health in older adults after hospitalization for ischemic heart disease (RESILIENT)
使用移动医疗对因缺血性心脏病住院的老年人进行家庭康复(RESILIENT)
- 批准号:
10165452 - 财政年份:2019
- 资助金额:
$ 66.04万 - 项目类别:
Rehabilitation at home using mobile health in older adults after hospitalization for ischemic heart disease (RESILIENT)
使用移动医疗对因缺血性心脏病住院的老年人进行家庭康复(RESILIENT)
- 批准号:
10450751 - 财政年份:2019
- 资助金额:
$ 66.04万 - 项目类别:
BETTER-BP (Behavioral Economics Trial To Enhance Regulation of Blood Pressure)
BETTER-BP(加强血压调节的行为经济学试验)
- 批准号:
10468046 - 财政年份:2019
- 资助金额:
$ 66.04万 - 项目类别:
BETTER-BP (Behavioral Economics Trial To Enhance Regulation of Blood Pressure)
BETTER-BP(加强血压调节的行为经济学试验)
- 批准号:
10678781 - 财政年份:2019
- 资助金额:
$ 66.04万 - 项目类别:
BETTER-BP (Behavioral Economics Trial To Enhance Regulation of Blood Pressure)
BETTER-BP(加强血压调节的行为经济学试验)
- 批准号:
10019587 - 财政年份:2019
- 资助金额:
$ 66.04万 - 项目类别:
Rehabilitation at home using mobile health in older adults after hospitalization for ischemic heart disease (RESILIENT)
使用移动医疗对因缺血性心脏病住院的老年人进行家庭康复(RESILIENT)
- 批准号:
10604354 - 财政年份:2019
- 资助金额:
$ 66.04万 - 项目类别:
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