Community Violence as a Social Risk Factor for Cardiometabolic Diseases: Neighborhood Dynamics From Structures to Self
社区暴力作为心血管代谢疾病的社会风险因素:从结构到自我的邻里动态
基本信息
- 批准号:9976579
- 负责人:
- 金额:$ 16.33万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-07-15 至 2024-05-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdolescentAdultAmericanAreaAttitudeBiological MarkersBiological SciencesBusinessesCaringCensusesCharacteristicsChicagoCitiesClinical InvestigatorColorCommunitiesCommunity SurveysCrimeDataData ScienceDevelopment PlansDiseaseDisease ManagementDisease OutcomeDyslipidemiasEducational CurriculumEnvironmentEpidemiologistEpidemiologyEventExposure toFocus GroupsFoundational SkillsFutureGovernmentHealthHealth ResourcesHealth behaviorHealth care facilityHealthcareHomicideHypertensionIndividualInfrastructureInstitutionInterventionLeadLifeLife Cycle StagesLife Style ModificationLinkLongitudinal StudiesMediatingMedicineMentorshipMethodologyMethodsNamesNeighborhoodsNeurosecretory SystemsObesityOutcomeParticipantPathway interactionsPatientsPersonsPharmacy facilityPhysical activityPhysical environmentPolicePovertyProcessProviderRecurrenceResearchResearch DesignResearch InstituteResearch PersonnelResearch ProposalsResourcesRiskRisk FactorsRoleSeriesSocial EnvironmentSocial InteractionSocial WorkSocial isolationSocial supportStatistical Data InterpretationStressStructureTestingTimeTrainingTraining ProgramsTraining and InfrastructureTransportationTraumaTweensUniversitiesViolenceVulnerable PopulationsWorkbasebiological adaptation to stressbuilt environmentcardiometabolic riskcardiometabolismcareercareer developmentcohortdesignempowermentepidemiology studyevidence baseexperiencefollow-upimprovedindexinginstructorlongitudinal analysismiddle agepopulation basedpopulation healthresilienceresponserobberyskillssocialsocial health determinantsspatiotemporalsystems researchtraining opportunityviolence exposureviolent crime
项目摘要
PROJECT ABSTRACT
This research proposal contains a five year career development plan that will establish me as a social
epidemiologist who focuses on social risk factors for cardiometabolic diseases. I am an Instructor of Medicine
in the Biological Sciences Division at the University of Chicago. Building on my prior work and training on the
social determinants of health, I will focus on a particularly detrimental social risk factor facing many high-
poverty, urban communities of color: community violence. The proposed training plan will combine didactic and
practical experiences to equip me with training in spatial data science, longitudinal methods, and intervention-
based research, all advanced methodological skills in epidemiology and population health. It will also provide
me with needed training and infrastructure to develop expertise in cardiometabolic disease outcomes, which
have been frequently linked to community violence in epidemiological studies. My mentorship team and
advisory panel have demonstrated excellence in these areas of research and are committed to my career
development. This training opportunity will galvanize my transition to independence as a clinician-investigator
who develops evidence-based strategies to improve the cardiometabolic health of vulnerable populations.
Community violence is an important social risk factor for cardiometabolic diseases. Community violence can
increase risk for cardiometabolic diseases through pathophysiologic processes, such as stress or
neuroendocrine responses, or by influencing health behaviors (e.g., reduced physical activity). However, the
role of neighborhood-level processes (e.g., loss of built environment resources, social distrust and isolation),
and how these processes can be targeted, remains poorly understood. I have shown that frequent and
persistent exposure to violence may be a stronger predictor of cardiometabolic diseases than isolated, life-
threatening events. My central hypothesis is that community violence, when frequent and concentrated, can
trigger stress-response pathways on both individual and neighborhood levels to augment risk for poor
cardiometabolic outcomes. I will examine specific response pathways in the neighborhood environment that
mitigate risk or build resilience to community violence in vulnerable populations. The proposed specific aims
are to: 1) Examine the spatiotemporal relationship between community violence and built environment
characteristics in U.S. cities; 2) Determine the built and social environment characteristics that influence the
relationship between community violence and cardiometabolic diseases across the life course; and 3) Develop
and pilot a patient- and stakeholder-informed healthcare intervention to address the cardiometabolic health
effects of violence. The overall objective of this research proposal is to examine community violence as a
social risk factor for cardiometabolic diseases, and specifically elucidate the neighborhood dynamics that
influence this relationship—from structures to social settings to self. Accomplishing these aims will pave the
way for implementing and evaluating an integrated, population-based health intervention in a future R01.
项目摘要
这份研究计划书包含了一个五年的职业发展计划,这将使我成为一个社会
流行病学家,专注于心脏代谢疾病的社会风险因素。我是一名医学讲师
在芝加哥大学的生物科学部。基于我之前的工作和培训,
健康的社会决定因素,我将集中在一个特别有害的社会风险因素面临许多高-
贫困,城市有色人种社区:社区暴力。拟议的培训计划将联合收割机教学和
实践经验,使我具备空间数据科学,纵向方法和干预方面的培训-
基于研究,所有先进的流行病学和人口健康的方法技能。它还将提供
为我提供所需的培训和基础设施,以发展心脏代谢疾病结局方面的专业知识,
在流行病学研究中经常与社区暴力联系在一起。我的导师团队和
顾问团在这些研究领域表现出卓越的表现,并致力于我的职业生涯
发展这个培训机会将激励我过渡到独立作为一个临床调查员
世卫组织制定循证战略,以改善弱势群体的心脏代谢健康。
社区暴力是心脏代谢疾病的重要社会危险因素。社区暴力可以
通过病理生理过程,如压力或
神经内分泌反应,或通过影响健康行为(例如,减少体力活动)。但
邻域级过程的作用(例如,建筑环境资源的丧失、社会不信任和孤立),
以及如何针对这些过程,仍然知之甚少。我已经表明,频繁和
持续暴露于暴力可能是心脏代谢疾病的一个更强的预测比孤立的,生活-
威胁事件。我的中心假设是,社区暴力,当频繁和集中,
在个人和社区层面上触发压力反应途径,以增加穷人的风险
心脏代谢结局。我将研究在邻近环境中的具体反应途径,
在弱势群体中减轻风险或建立对社区暴力的复原力。拟议的具体目标
1)研究社区暴力与建筑环境之间的时空关系
2)确定影响美国城市的建筑和社会环境特征;
社区暴力与整个生命过程中的心脏代谢疾病之间的关系;以及3)发展
并试点患者和患者知情的医疗干预,以解决心脏代谢健康
暴力的影响。这项研究提案的总体目标是审查社区暴力,
心脏代谢疾病的社会风险因素,并特别阐明邻里动态,
影响这种关系--从结构到社会环境再到自我。实现这些目标将为
在未来的R 01中实施和评估综合的、基于人群的健康干预的方式。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Elizabeth Lunjun Tung其他文献
Elizabeth Lunjun Tung的其他文献
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{{ truncateString('Elizabeth Lunjun Tung', 18)}}的其他基金
Community Violence as a Social Risk Factor for Cardiometabolic Diseases: Neighborhood Dynamics From Structures to Self
社区暴力作为心血管代谢疾病的社会风险因素:从结构到自我的邻里动态
- 批准号:
10443597 - 财政年份:2019
- 资助金额:
$ 16.33万 - 项目类别:
Community Violence as a Social Risk Factor for Cardiometabolic Diseases: Neighborhood Dynamics From Structures to Self
社区暴力作为心血管代谢疾病的社会风险因素:从结构到自我的邻里动态
- 批准号:
10626084 - 财政年份:2019
- 资助金额:
$ 16.33万 - 项目类别:
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