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Perceptual Learning and Memory Consolidation in Adults with and without Language Impairment

有或没有语言障碍的成年人的知觉学习和记忆巩固

基本信息

批准号：
9975836
负责人：
Frances Sayako Earle
金额：
$ 15.6万
依托单位：
UNIVERSITY OF DELAWARE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-01 至 2022-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9975836
关键词：
Achievement Acoustics Address Adult Affect Area Behavioral Categories Cognitive Data Developmental Disabilities Discrimination Disease Dissociation Education Etiology Face Failure Functional Magnetic Resonance Imaging Hippocampus (Brain)Imaging Techniques Impairment Individual Individual Differences Inferior frontal gyrus Knowledge Language Language Development Learning Learning Disabilities Left Legal Linguistics Literature Magnetic Resonance Measures Memory Outcome Pattern Perceptual learning Performance Population Process Protocols documentation Recording of previous events Reporting Research Sleep Speech Speech Discrimination Speech Perception Speech Sound Superior temporal gyrus Symptoms System Testing Time Training Vocation Work attenuation auditory processing base experience imaging study improved innovation language impairment learned behavior memory consolidation memory encoding neuromechanism non-Native novel phonology procedural memory programs public health relevance recruit relating to nervous system remediation sound specific language impairment stem theories young adult

项目摘要

PROJECT SUMMARY There are lifelong challenges faced by adults with (Specific) Language Impairment (LI), a common learning disability that affects 7% of the US population (Tomblin et al., 1997). Despite documented difficulties in educational attainment, vocational outcome, and legal standing for adults with LI (Bryan et al., 2007; Conti- Ramsden et al.,2009; Johnson et al.,2010), research on adults with LI have been all but been ignored in the literature. As a result, we know very little about the barriers to educational and vocational attainment faced by young adults with LI, such as the potential impairment in learning and memory. Our recent work has found that, following perceptual training on new (nonnative) acoustic-phonetic information, sleep facilitates improved perceptual ability in adults with typical language, but not in adults with a history of LI. How memory consolidation in perceptual learning relates to broader memory encoding in LI is not yet clear. To this end, we aim to establish how performance on these tasks inform relative strengths and weaknesses in well-understood memory systems: specifically, procedural and declarative memory. Furthermore, we must understand the neural mechanism underlying this observed behavioral failure in offline consolidation. Therefore, the research outlined in this proposal seeks to determine the association between perceptual learning and declarative and procedural memory, and to identify the neural mechanism underlying the behavioral phenomenon of consolidation failure in LI. Our aims will be addressed by combining behavioral data in established procedural and declarative learning tasks with our perceptual learning task. We will also extend our behavioral protocol on perceptual learning to investigate neural processing of trained speech sounds before and after sleep using functional magnetic resonance imaging (fMRI) techniques. The knowledge to be gained through this research will inform the time course of memory consolidation in individuals with LI, and inform the cognitive substrates of speech sound acquisition in adulthood more broadly. Furthermore, by defining a potentially critical obstacle to achievement, this knowledge may contribute to improving remediation outcomes for young adults with this common developmental disability. The knowledge to be gained through the proposed project will contribute to four areas of research: (Specific) Language Impairment, speech perception, second language learning, and memory consolidation. .

项目总结