Transdisciplinary Research in Energetics and Cancer (TREC) Training Grant

 描述（由申请人提供）：鉴于肥胖、不良饮食和缺乏身体活动（结合称为“能量平衡”或“能量学”）的患病率不断上升，以及这些因素与癌症的关联，需要创新研究、临床护理和科学家培训来降低这些风险因素的患病率，从而降低癌症发病率和死亡率。该NCI R25研究教育计划的总体目标是开发，提供，评估并最终传播每年为期5天的能量学和癌症（TREC）跨学科研究培训课程，以提高课程参与者在能量学和癌症研究和临床护理方面进行创新，跨学科研究的能力。拟议的课程建立在NCI TREC计划的基础上，该计划是2005年至2016年的一项重大科学研究工作，将涵盖癌症控制连续体的主题，包括预防，检测，诊断，治疗和生存。对TREC的资助将于2016年停止，但我们的目标是通过拟议的为期5天的年度TREC课程继续推进TREC培训科学家的使命。拟议的R25 TREC培训课程，由梅琳达欧文，博士，公共卫生硕士（TREC培训和教育主任从2005-2016年），将包括一个跨学科的团队，由来自不同背景的20名专家教师组成，汇集了TREC相关研究，指导和培训的互补技能和专业知识。我们建议的课程是高度创新的，因为目前没有培训机会，课程或研讨会存在，重点是能量学和癌症。为期5天的年度课程将提供最先进的，以证据为基础的能量学和癌症教育和培训。培训新的领导者将有助于传播和实施有效的癌症预防和控制生活方式战略，因为他们将进行转化研究以降低风险， 与癌症相关的死亡率、发病率和成本。

 DESCRIPTION (provided by applicant): Given the rising prevalence of obesity, poor diet and physical inactivity, known in combination as "energy balance" or "energetics", as well as their associations of these factors with cancer, innovative research, clinical care and training of scientists are needed to lower the prevalence of these risk factors and in turn, lower cancer incidence and mortality rates. The overall goal of this NCI R25 research education program is to develop, offer, evaluate and eventually disseminate an annual 5-day transdisciplinary research in energetics and cancer (TREC) training course for postdoctoral fellows and early career investigators with the goal of enhancing the ability of course participants to conduct innovative, transdisciplinary research in energetics and cancer research and clinical care. The proposed course builds upon the NCI TREC Initiative, which was a major scientific research effort that occurred from 2005 to 2016, and will cover topics across the cancer control continuum, including prevention, detection, diagnosis, treatment and survivorship. Funding for TREC will cease in 2016, however our goal is to continue to further the TREC mission of training scientists via the proposed 5- day annual TREC course. The proposed R25 TREC Training Course, led by Melinda Irwin, PhD, MPH (TREC Director of Training and Education from 2005-2016), will include a transdisciplinary team of 20 expert faculty members from diverse backgrounds, bringing together complementary skills and expertise in TREC-related research, mentoring and training. Our proposed course is highly innovative in that currently no training opportunity, course, or workshop exists that focuses on energetics and cancer. The annual 5-day course will provide state-of-the-art, evidence-based energetics and cancer education and training. Training new leaders will assist in dissemination and implementation of effective lifestyle strategies for cancer prevention and control, as they will carry out the translational research to lower the risk, mortality, morbidity and costs associated with cancer.