Preventing Risky Drinking and PTSD After Sexual Assault: A Web-Based Intervention

拟议的独立之路奖的长期目标是支持申请者 建立独立的研究计划，支持她向独立研究科学家的转变 担任助理教授的职位。总的来说，到目前为止，她的研究已经调查了 创伤康复，重点是这些过程发生的社会背景，她最近 开始检查酒精使用是创伤的结果。她打算改变她的博士后研究训练 从了解创伤后饮酒的病因学机制到创造和测试 以技术为基础的干预措施，防止创伤后高风险饮酒的发展。这些 目标将通过一项为期5年的培训计划来实现，申请者将在该计划中获得技能和 通过导师指导、课程作业、研讨会、 讲习班和国家会议。研究计划的长期目标是开发一个有效的网络-- 基于早期干预策略的减少性侵犯女性幸存者的高风险饮酒和创伤后应激障碍 (SA)，鉴于SA是该人群中一种特别常见和有害的创伤形式，通常 与共同发生的饮酒问题和创伤后应激障碍有关。干预将适应现有的基于证据的 以与理论和研究相一致的方式进行实践，以期通过增加社会 支持和减轻负面社会反应的危害(例如，指责受害者)。K99阶段将涉及 实现具体目标1和2。具体目标1，即利用现有的专门知识来源 通知开发的原型干预，将通过参考现有的临床完成 手册，并与社区利益相关者进行定性访谈和焦点小组 南澳的幸存者。具体目标2涉及从幸存者那里获得反馈，以告知改善 原型干预的可用性和用户满意度。具体目标3(即评估参与者 对干预的反应)和4(即评估干预对学习和症状的影响) 在R00阶段通过对有以下情况的妇女进行干预的可行性试验来完成 最近被性侵了。这项研究将为R01提交给NIAAA提供试点数据 R00阶段，将在随机对照试验中测试干预的效果。Kaysen博士、Edwards博士、Rhew博士和 Areán将担任该奖项的导师，并提供酒精研究、干预等领域的专业知识 以社会支持、随机对照试验、统计和基于技术的干预为目标。这个 华盛顿大学的培训环境非常有利于发展技能和专长 需要过渡到酒精研究领域的独立研究科学家的角色 技术创新。提议的奖励与NIH开发新的独立的目标一致 在其内容领域具有很强技能的调查人员，他们对NIH的资金具有竞争力。

The long-term objectives of the proposed Pathway to Independence Award are to support the applicant in building an independent program of research, and support her transition into an independent research scientist in an assistant professor position. Broadly, her research to date has investigated facilitators of and barriers to trauma recovery, with a focus on the social contexts in which these processes occur, and she has recently begun examining alcohol use as an outcome of trauma. She intends to shift her postdoctoral research training from understanding mechanisms involved in the etiology of drinking after trauma to the creation and testing of technologically-based interventions to prevent the development of high-risk drinking after trauma. These objectives will be achieved through a 5-year training plan in which the applicant will acquire the skills and expertise necessary to establish her program of research through mentorship, coursework, seminars, workshops, and national conferences. The long-term goal of the research plan is to develop an effective web- based early intervention strategy to mitigate high-risk drinking and PTSD in female survivors of sexual assault (SA), given that SA is a particularly common and deleterious form of trauma in this population that is commonly associated with co-occurring drinking problems and PTSD. The intervention will adapt existing evidence-based practices in a manner consistent with theory and research to target these outcomes by increasing social support and mitigating the harm of negative social reactions (e.g., victim blame). The K99 phase will involve the accomplishment of Specific Aims 1 and 2. Specific Aim 1, which is to use existing sources of expertise to inform the development of a prototype intervention, will be accomplished by consulting existing clinical manuals and conducting qualitative interviews and focus groups with community stakeholders serving survivors of SA. Specific Aim 2 involves eliciting feedback from survivors to inform changes that improve the usability of and user satisfaction with the prototype intervention. Specific Aims 3 (i.e., assess participant reaction to the intervention) and 4 (i.e., assess the impact of the intervention on learning and symptoms) will be accomplished in the R00 phase via a feasibility trial of the intervention with a sample of women who have recently been sexually assaulted. This research will provide pilot data for an R01 submission to NIAAA during the R00 phase which will test the efficacy of the intervention in an RCT. Drs. Kaysen, Edwards, Rhew, and Areán will serve as mentors for this award and offer expertise in the areas of alcohol research, interventions targeting social support, randomized controlled trials, statistics, and technology-based interventions. The University of Washington training environment is highly conducive to developing the skills and expertise needed to transition into a role as an independent research scientist in the area of alcohol research and technological innovation. The proposed award is consistent with NIH's goal of developing new independent investigators with strong skills in their content area who are competitive for NIH funding.