Developmental Research Program

DRP：发展研究计划 摘要/摘要 加州大学洛杉矶分校脑癌发展研究项目(DRP)的目标是培养 通过资助先导发展研究项目探索创新研究思路 脑癌领域。该计划将确定新的、创新的项目以获得资金，这些项目将不断更新 我们的脑孢子研究组合的活力，并增加、增强或取代当前的主要研究 项目。DRP代表了一种在孢子内扩大发现的及时机制。每年，有三个 具有高度创新性的提案将被选为资金来源。未来的发展研究项目将是 通过在整个加州大学洛杉矶分校主校区和附属机构发送的申请请求(RFA)进行征集 机构(即，洛杉矶生物医学/加州大学洛杉矶分校港口医学中心，查尔斯·德鲁医学和科学大学， 西洛杉矶退伍军人管理医院、南加州凯撒永久医院和锡达斯-西奈 医疗中心)。我们还将通过其他机构范围、全州范围和 区域范围内的频道。这将包括向加州大学洛杉矶分校和其他加州大学的所有教职员工发送电子邮件征集 加州校园(伯克利、戴维斯、欧文、河滨、圣地亚哥、圣巴巴拉和圣克鲁斯) 至于加州理工大学和南加州大学的研究人员。我们还将通过NCI资助的主要癌症项目征集申请 南加州癌症中心(加州大学洛杉矶分校琼森癌症中心、南加州大学诺里斯癌症中心、希望之城 癌症中心，UCI Chao家族癌症中心，UCSD摩尔斯癌症中心，Sanford-Burnham Research 和索尔克研究所)。潜在的DRP调查人员将被要求提供一份建议书、生物草图和 推荐信。每年将颁发三个奖项，每个奖项50,000美元(每年总计150,000美元) 在孢子奖的有效期内。资金将主要用于新的和创新的想法，但也将 启动孢子内和孢子间的协作。将鼓励各级教职员工申请，这两项 开始了研究生涯，并建立了希望将他们的研究重新定向到 脑癌。这应该会提供一个广泛的申请者基础和新的想法，提供资金机会 供来自当地和区域机构的调查人员使用。民进党推选委员会将召开会议并 选择最有价值的脑癌翻译研究应用程序，并从外部临时提供意见 如有必要，请审阅。在DRP遴选委员会打分后，执行委员会(EC) 将开会确定资金额度。内部咨询委员会(IAB)和外部咨询委员会(EAB) 将在定期会议上审查发展项目的供资决定和进展情况。 DRP将从琼森综合癌症中心(JCCC)和加州大学洛杉矶分校获得匹配资金 神经外科。成功的翻译研究项目可能会在 淘汰和置换非生产性资金重大项目。DRP的预期结果是扩大 加州大学洛杉矶分校的整个脑癌孢子调查员队伍。

DRP: Developmental Research Program SUMMARY/ABSTRACT The goal of the UCLA SPORE in Brain Cancer Developmental Research Program (DRP) is to foster the exploration of innovative research ideas through the funding of pilot developmental research projects in the field of brain cancer. This program will identify new, innovative projects for funding that will constantly renew the vigor of our Brain SPORE research portfolio and add to, augment, or replace current major research projects. The DRP represents a timely mechanism to expand discovery within the SPORE. Each year, three highly innovative proposals will be selected for funding. Prospective developmental research projects will be solicited through a request for applications (RFA) sent throughout the UCLA main campus and affiliated institutions (i.e., LA BioMed/UCLA Harbor Medical Center, Charles Drew University of Medicine and Science, West Los Angeles Veterans Administration Hospital, Southern California Kaiser Permanente, and Cedars-Sinai Medical Center). We will also solicit proposals for our DRP through other institution-wide, state-wide, and region-wide channels. This will include e-mail solicitations to all faculty at UCLA and other University of California campuses (Berkeley, Davis, Irvine, Riverside, San Diego, Santa Barbara, and Santa Cruz), as well as to researchers at Caltech and USC. We will also solicit applications through the major NCI-funded Cancer Centers in Southern California (UCLA Jonsson Cancer Center, USC Norris Cancer Center, City of Hope Cancer Center, UCI Chao Family Cancer Center, UCSD Moores Cancer Center, Sanford-Burnham Research Institute, and the Salk Institute). Potential DRP investigators will be asked for a proposal, biosketch, and letters of recommendation. Three awards of $50,000 each (totaling $150,000 per year) will be made annually for the duration of the SPORE award. Funding will be made primarily for new and innovative ideas, but also to initiate intra- and inter-SPORE collaborations. Faculty at all levels will be encouraged to apply, both those beginning a research career, and established investigators who wish to re-direct their research into the field of brain cancer. This should provide a broad base of applicants and new ideas, providing funding opportunities for investigators from a variety of local and regional institutions. The DRP Selection Committee will meet and select the most meritorious translational brain cancer research applications, with input from outside ad hoc reviewers as necessary. Following scoring by the DRP Selection Committee, the Executive Committee (EC) will meet to determine the funding line. The Internal Advisory Board (IAB) and External Advisory Board (EAB) will review the funding decisions and progress of developmental projects at their regularly scheduled meetings. The DRP will receive matching funds from the Jonsson Comprehensive Cancer Center (JCCC) and the UCLA Department of Neurosurgery. Successful translational research projects may receive further funding in the SPORE and replace unproductive funded major projects. The anticipated outcome of the DRP is to enlarge the overall pool of brain cancer SPORE investigators at UCLA.