Developmental Research Program

发展研究计划 总结/摘要 加州大学洛杉矶分校脑癌发展研究计划（DRP）的目标是培养 通过资助发展研究试验项目， 脑癌领域。该计划将确定新的，创新的项目的资金，将不断更新 我们的大脑孢子研究组合的活力，并添加，增强或取代目前的主要研究 项目DRP代表了在SPORE内扩展发现的及时机制。每年都有三位 并会挑选具创意的建议获得拨款。未来的发展研究项目将 通过申请请求（RFA）在整个UCLA主校区和附属机构发送征求 机构（即，洛杉矶生物医学/加州大学洛杉矶分校海港医疗中心，查尔斯德鲁医学和科学大学， 西洛杉矶退伍军人管理局医院、南加州凯撒医疗机构和雪松西奈 医疗中心）。我们还将通过其他机构范围内的，全州范围内的， 全区域渠道。这将包括向加州大学洛杉矶分校和其他加州大学洛杉矶分校的所有教师发送电子邮件。 加州校区（伯克利、戴维斯、欧文、滨江、圣地亚哥、圣巴巴拉和圣克鲁斯）也是如此 加州理工和南加州大学的研究人员。我们亦会透过NCI-Funded Cancer 南加州的中心（加州大学洛杉矶分校琼森癌症中心，南加州大学诺里斯癌症中心，希望之城 癌症中心，UCI Chao家庭癌症中心，UCSD Moores癌症中心，Sanford-Burnham研究 研究所和索尔克研究所）。潜在的DRP调查人员将被要求提交一份提案，biosketch， 推荐信。每年将颁发三个奖项，每个奖项5万美元（每年总计15万美元） 在获得SPORE奖期间。资金将主要用于新的和创新的想法，但也 启动SPORE内部和内部协作。各级教师将被鼓励申请，这两个 开始了研究生涯，并建立了调查谁希望重新引导他们的研究领域， 脑癌这将提供广泛的申请人基础和新的想法，提供资助机会 为来自各种地方和区域机构的调查人员提供服务。DRP遴选委员会将举行会议， 选择最有价值的转化脑癌研究应用程序，并从外部特别输入 必要时审查。在DRP评选委员会评分后，执行委员会（EC） 将开会决定资金额度内部咨询委员会（IAB）和外部咨询委员会（EAB） 在定期举行的会议上检讨拨款决定和发展项目的进度。 DRP将从琼森综合癌症中心（JCCC）和加州大学洛杉矶分校获得配套资金 神经外科。成功的转化研究项目可能会在 支持和取代非生产性资助的重大项目。DRP的预期结果是扩大 加州大学洛杉矶分校的脑癌SPORE研究人员。

DRP: Developmental Research Program SUMMARY/ABSTRACT The goal of the UCLA SPORE in Brain Cancer Developmental Research Program (DRP) is to foster the exploration of innovative research ideas through the funding of pilot developmental research projects in the field of brain cancer. This program will identify new, innovative projects for funding that will constantly renew the vigor of our Brain SPORE research portfolio and add to, augment, or replace current major research projects. The DRP represents a timely mechanism to expand discovery within the SPORE. Each year, three highly innovative proposals will be selected for funding. Prospective developmental research projects will be solicited through a request for applications (RFA) sent throughout the UCLA main campus and affiliated institutions (i.e., LA BioMed/UCLA Harbor Medical Center, Charles Drew University of Medicine and Science, West Los Angeles Veterans Administration Hospital, Southern California Kaiser Permanente, and Cedars-Sinai Medical Center). We will also solicit proposals for our DRP through other institution-wide, state-wide, and region-wide channels. This will include e-mail solicitations to all faculty at UCLA and other University of California campuses (Berkeley, Davis, Irvine, Riverside, San Diego, Santa Barbara, and Santa Cruz), as well as to researchers at Caltech and USC. We will also solicit applications through the major NCI-funded Cancer Centers in Southern California (UCLA Jonsson Cancer Center, USC Norris Cancer Center, City of Hope Cancer Center, UCI Chao Family Cancer Center, UCSD Moores Cancer Center, Sanford-Burnham Research Institute, and the Salk Institute). Potential DRP investigators will be asked for a proposal, biosketch, and letters of recommendation. Three awards of $50,000 each (totaling $150,000 per year) will be made annually for the duration of the SPORE award. Funding will be made primarily for new and innovative ideas, but also to initiate intra- and inter-SPORE collaborations. Faculty at all levels will be encouraged to apply, both those beginning a research career, and established investigators who wish to re-direct their research into the field of brain cancer. This should provide a broad base of applicants and new ideas, providing funding opportunities for investigators from a variety of local and regional institutions. The DRP Selection Committee will meet and select the most meritorious translational brain cancer research applications, with input from outside ad hoc reviewers as necessary. Following scoring by the DRP Selection Committee, the Executive Committee (EC) will meet to determine the funding line. The Internal Advisory Board (IAB) and External Advisory Board (EAB) will review the funding decisions and progress of developmental projects at their regularly scheduled meetings. The DRP will receive matching funds from the Jonsson Comprehensive Cancer Center (JCCC) and the UCLA Department of Neurosurgery. Successful translational research projects may receive further funding in the SPORE and replace unproductive funded major projects. The anticipated outcome of the DRP is to enlarge the overall pool of brain cancer SPORE investigators at UCLA.