Developmental Research Program
发展研究计划
基本信息
- 批准号:10673782
- 负责人:
- 金额:$ 11.81万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-08-11 至 2027-07-31
- 项目状态:未结题
- 来源:
- 关键词:AwardBrainCollaborationsCommunitiesComprehensive Cancer CenterDataDevelopmentDiagnosisDisciplineEthnic OriginFacultyFosteringFundingFunding OpportunitiesGenerationsGoalsGrantGrowthInstitutionInterdisciplinary StudyMalignant neoplasm of brainMissionMonitorOutcomePilot ProjectsProcessProductivityProgram Research Project GrantsProgress ReportsQualifyingRaceRequest for ApplicationsResearchResearch InstituteResearch PersonnelResearch Project GrantsReview CommitteeSourceTranslational ResearchUnderrepresented Minorityanticancer researchbasebrain researchcancer preventioncareergender diversityhigh rewardhigh riskinnovationinterdisciplinary collaborationmedical schoolsminority investigatornovelprogramsprospectivesuccesstranslational potential
项目摘要
PROJECT SUMMARY/ABSTRACT – Developmental Research Program (DRP)
The goal of the UCLA SPORE in Brain Cancer Developmental Research Program (DRP) is to foster the
exploration of innovative research ideas through the funding of pilot developmental research projects in the
field of brain cancer. This program identifies new, innovative projects for funding that will constantly renew the
vigor of our Brain SPORE research portfolio and add to, augment, or replace current major research projects.
The DRP serves as a source of pilot funding and a timely mechanism to expand discovery within the SPORE.
Each year, 2 – 3 highly innovative proposals are selected for funding at $50,000 - $75,000 each. Prospective
developmental research projects are solicited through a request for applications (RFA) sent throughout the
UCLA main campus and affiliated institutions via institution-wide and region-wide channels through the UCLA
David Geffen School of Medicine (DGSOM), the Jonsson Comprehensive Cancer Center (JCCC), and the
Brain Research Institute (BRI). Faculty at all levels are encouraged to apply, both those beginning a research
career and established investigators who wish to re-direct their research into the field of brain cancer. This
provides a broad base of applicants and new ideas, and allows funding opportunities for investigators from a
variety of local and regional institutions. The DRP Selection Committee meets and selects the most
meritorious translational brain cancer research applications, with input from outside ad hoc reviewers as
necessary.
Funding is made primarily for new and innovative ideas/projects, but also to initiate intra- and inter-SPORE
collaborations. We anticipate funding of at least one underrepresented minority (URM) investigator's project
per year in the next funding cycle, and have identified a pipeline of potential URM candidates. The DRP will
receive supplemental funds from the UCLA David Geffen School of Medicine (DGSOM) Dean's Office and the
Jonsson Comprehensive Cancer Center (JCCC), which will allow for rapid and nimble funding of important new
initiatives within the scope of our overall SPORE research goals. The priority for funding will be those
initiatives/projects considered of highest scientific merit and with translational potential and relevance to the
overall mission of the UCLA Brain SPORE. Successful translational research projects may receive further
funding in the SPORE and replace unproductive funded major projects. The anticipated outcome of the DRP
is to enlarge the overall pool of brain cancer SPORE investigators at UCLA and to increase the diversity of our
Brain Cancer SPORE research portfolio.
项目总结/摘要-开发研究计划(DRP)
加州大学洛杉矶分校脑癌发展研究计划(DRP)的目标是培养
通过资助发展研究试验项目,
脑癌领域。该计划确定了新的,创新的资助项目,将不断更新,
我们的大脑孢子研究组合的活力,并添加,增强或取代目前的主要研究项目。
DRP是试点资金的来源,也是在SPORE内扩大发现的及时机制。
每年选出2 - 3个高度创新的提案,每个提案获得50 000 - 75 000美元的资助。前瞻性
发展研究项目是通过在整个申请(RFA)的要求征求
UCLA主校区和附属机构通过机构范围和区域范围的渠道,通过UCLA
大卫格芬医学院(DGSOM),琼森综合癌症中心(JCCC)和
大脑研究所(BRI)。鼓励各级教师申请,无论是那些开始研究
职业和建立的研究人员谁希望重新引导他们的研究到脑癌领域。这
提供了广泛的申请人和新的想法,并允许从一个研究人员的资金机会,
各种地方和区域机构。DRP遴选委员会召开会议,
有价值的转化脑癌研究应用,与外部特设审查员的输入,
必要
资金主要用于新的和创新的想法/项目,但也用于启动内部和内部的SPORE
合作。我们预计至少有一个代表性不足的少数民族(URM)研究项目的资金
在下一个供资周期中,每年都有一个项目,并已确定了一批潜在的统一资源管理候选人。DRP将
从加州大学洛杉矶分校大卫格芬医学院(DGSOM)院长办公室和
琼森综合癌症中心(JCCC),这将允许快速和灵活的资金,重要的新的
在我们的总体SPORE研究目标范围内的举措。资金的优先事项将是
被认为具有最高科学价值、具有转化潜力和与《公约》相关性的倡议/项目
加州大学洛杉矶分校脑孢子的整体使命。成功的翻译研究项目可能会得到进一步的
在SPORE的资金,并取代非生产性资助的重大项目。DRP的预期结果
是扩大加州大学洛杉矶分校脑癌SPORE研究人员的整体库,并增加我们的多样性。
脑癌孢子研究组合。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Robert M Prins', 18)}}的其他基金
Neoadjuvant checkpoint blockade for recurrent glioblastoma
新辅助检查点阻断治疗复发性胶质母细胞瘤
- 批准号:
10343478 - 财政年份:2022
- 资助金额:
$ 11.81万 - 项目类别:
Neoadjuvant checkpoint blockade for recurrent glioblastoma
新辅助检查点阻断治疗复发性胶质母细胞瘤
- 批准号:
10661485 - 财政年份:2022
- 资助金额:
$ 11.81万 - 项目类别:
Identification and cloning of neoantigen-specific T cells for GBM immunotherapy
用于 GBM 免疫治疗的新抗原特异性 T 细胞的鉴定和克隆
- 批准号:
9903258 - 财政年份:2019
- 资助金额:
$ 11.81万 - 项目类别:
Identification and cloning of neoantigen-specific T cells for GBM immunotherapy
用于 GBM 免疫治疗的新抗原特异性 T 细胞的鉴定和克隆
- 批准号:
10599231 - 财政年份:2019
- 资助金额:
$ 11.81万 - 项目类别:
Identification and cloning of neoantigen-specific T cells for GBM immunotherapy
用于 GBM 免疫治疗的新抗原特异性 T 细胞的鉴定和克隆
- 批准号:
10375387 - 财政年份:2019
- 资助金额:
$ 11.81万 - 项目类别:
Project 1: Targeting immunotherapy-induced resistance with DC vaccination and PD-1/CSF-1R inhibition
项目 1:通过 DC 疫苗接种和 PD-1/CSF-1R 抑制来针对免疫治疗引起的耐药性
- 批准号:
10673749 - 财政年份:2017
- 资助金额:
$ 11.81万 - 项目类别:
Optimizing Induction Conditions for Immunotherapeutic CTL
优化免疫治疗 CTL 的诱导条件
- 批准号:
8704325 - 财政年份:2010
- 资助金额:
$ 11.81万 - 项目类别:
CNS Anti-tumor immunity induced by dendritic cell vaccination and TLR agonists
树突状细胞疫苗和 TLR 激动剂诱导的 CNS 抗肿瘤免疫
- 批准号:
7754039 - 财政年份:2007
- 资助金额:
$ 11.81万 - 项目类别:
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