Engaging residents to sustain healthier homes

让居民参与维持更健康的家园

• 批准号: 10352861
• 负责人: Robin E. Dodson
• 金额: $ 25.79万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-02 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10352861
• 关键词: Address; Asthma; Attention; Back; Biological; Biological Markers; Characteristics; Chemical Exposure; Chemicals; Child; Collaborations; Collection; Communities; Community Outreach; Control Groups; Data; Dictyoptera; Disease; Dissemination and Implementation; Dust; Education; Enrollment; Environmental Exposure; Environmental Hazards; Environmental Health; Etiology; Exposure to; Feedback; Flame Retardants; Foundations; Funding; Future; Goals; Hazard Controls; Health; Health Benefit; Health Surveys; Home; House Dust; Household; Housing; Individual; Intervention; Intervention Studies; Interview; Knowledge; Lead; Low income; Maternal and Child Health; Measurement; Measures; Molds; Monitor; Neighborhoods; New York; Organophosphates; Outcome; Participant; Patient Recruitments; Pesticides; Population; Pregnant Women; Primary Prevention; Program Sustainability; Randomized; Rehabilitation therapy; Reporting; Reproductive Health; Research; Resources; Sampling; Shapes; Surveys; Testing; Time; Toxic Environmental Substances; Urine; Visit; Woman; Work; aged; arm; base; community based research; community engaged research; community partnership; cost; design; digital; epidemiology study; group intervention; hazard; health disparity; high risk; household environmental exposure; improved; intervention cost; intervention program; lower income families; neurodevelopment; obesity-associated asthma; patient engagement; phthalates; post intervention; prevent; programs; recruit; reproductive; treatment group; urinary

The proposed project, “Engaging Residents to Sustain Healthier Homes,” builds on 20 years of community- academic partnership to address health disparities in Rochester, NY through reducing low income families’ exposures to environmental hazards. Our research evaluates a low-cost intervention to reduce home-based environmental exposures through home health surveys and urine samples. The home is a major contributor to environmental exposures, particularly for pregnant women and young children. These exposures have significant implications for lifelong health disparities. New York State has been conducting a Healthy Neighborhoods Program (HNP) with community outreach workers for the past 30 years that involves education, low cost supplies, and referral to resources. This sustainable, low-cost intervention program has been shown to reduce certain home hazards and improve asthma outcomes; however, the impact on residents’ exposures has yet to be quantified through environmental (house dust) or biological (urine) monitoring, which may elucidate connections to other health outcomes including adverse neurodevelopmental and reproductive health effects. We aim to determine the impact of the HNP on resident exposure and use these results to inform future studies on the potential of a low-cost community-based intervention to improve maternal and child health outcomes. The proposed project leverages an existing HUD-funded intervention study (ROC HOME) involving analysis of dust in the homes of low-income homeowners in Rochester, NY. Half of the ROC HOME participants are receiving the HNP intervention; the other half are controls. We propose to add urine measurements to participants recruited from both arms of the ongoing ROC HOME study to explore urinary biomarkers of home environmental exposures among an understudied population for whom the HNP holds great potential for promoting environmental health. We will recruit 60 reproductive-aged women from the 100 ROC HOME study participants, collecting urine samples at two time points. Aim 1 will compare urine concentrations of pesticides, phthalates, and flame retardants post HNP intervention between treatment and control groups and estimate the association between exposure concentrations measured in household dust and urinary metabolite concentrations. Aim 2 will assess participant engagement in the home interventions before and after receiving their personal exposure results through a community partnership. The data collected will provide critical information to shape the design of future, scalable intervention studies that can measure the exposure reductions and health benefits of home- based hazard reduction interventions. Our long-term goal is to inform implementation and dissemination of low- cost, sustainable, community-based healthy home programs to reduce maternal and children’s exposure to environmental toxicants and promote lifelong health.

拟议的项目“让居民参与维持更健康的家园”建立在20年的社区基础上- 学术伙伴关系，以解决健康差距在罗切斯特，纽约州通过减少低收入家庭， 暴露于环境危害。我们的研究评估了一种低成本的干预措施，以减少家庭为基础的 通过家庭健康调查和尿样分析环境暴露。家庭是一个主要的贡献者， 环境暴露，特别是孕妇和幼儿。这些暴露具有显著的 对终身健康差距的影响。纽约州一直在开展健康社区活动 在过去30年里，与社区外展工作者一起开展了一项涉及教育、低成本的方案（海地国家警察） 供应和资源转介。这种可持续的低成本干预计划已被证明可以减少 某些家庭危害和改善哮喘的结果;然而，对居民暴露的影响还没有 通过环境（室内灰尘）或生物（尿液）监测进行量化， 与其他健康结果的联系，包括对神经发育和生殖健康的不良影响。 我们的目标是确定HNP对居民暴露的影响，并利用这些结果为未来的研究提供信息 关于低成本社区干预改善妇幼保健成果的潜力。的 拟议的项目利用了现有的住房和城市发展部资助的干预研究（ROC HOME），涉及粉尘分析 在纽约州罗切斯特的低收入房主家中。一半的ROC HOME参与者正在接受 另一半是对照组。我们建议在招募的参与者中加入尿液测量 来自正在进行的ROC HOME研究的两组，以探索家庭环境的尿液生物标志物。 暴露在未充分研究的人群中，对他们来说，HNP具有很大的促进潜力， 环境卫生。我们将从100名ROC HOME研究参与者中招募60名育龄妇女， 在两个时间点收集尿液样品。目标1将比较尿液中杀虫剂，邻苯二甲酸盐， 和阻燃剂后HNP干预治疗组和对照组之间，并估计关联 在家庭灰尘中测量的接触浓度与尿液代谢物浓度之间存在差异。目标2将 评估参与者在接受个人接触之前和之后参与家庭干预的情况 通过社区合作取得成果。收集的数据将为设计提供关键信息 未来，可扩展的干预研究，可以衡量暴露减少和健康效益的家庭- 减少灾害的干预措施。我们的长期目标是为实施和传播低- 成本，可持续的，以社区为基础的健康家庭计划，以减少孕产妇和儿童的接触， 环境毒物并促进终身健康。