A Dynamic COVID-19 Community-Engaged Testing Strategy in Alabama (COVID COMET AL)

阿拉巴马州动态的 COVID-19 社区参与测试策略 (COVID COMET AL)

• 批准号: 10355693
• 负责人: Renee A. Heffron
• 金额: $ 156.2万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-23 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10355693
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Aging; Alabama; Area; Award; Basic Science; Behavioral; Behavioral Sciences; Biology; Budgets; COVID-19; Caring; Clinical; Clinical Data; Clinical Research; Collaborations; Communication; Communities; Computerized Medical Record; Core Facility; Culture Techniques; Database Management Systems; Development; Discipline; Disease; Educational workshop; Effectiveness; Evolution; Extramural Activities; Faculty; Faculty Recruitment; Flow Cytometry; Fostering; Funding; Grant; HIV; Human immunodeficiency virus test; Institutes; Interdisciplinary Study; International; Intervention; Intervention Studies; Investments; Leadership; Link; Location; Mentors; Methodology; Methods; Mission; Molecular Virology; NIH Grants and Contracts; Outcomes Research; Outsourcing; Pathogenesis; Peer Review; Prevention; Prevention Research; Process; Productivity; Program Development; Publications; Research; Research Activity; Research Design; Research Personnel; Research Project Grants; Research Support; Resource Sharing; Resources; Risk Assessment; Services; Southeastern United States; Specimen; Spirituality; Statistical Data Interpretation; Strategic Planning; Testing; Therapeutic; Tissue Procurements; Tissue Transplantation; Training; Training Support; Translational Research; Treatment Efficacy; Underrepresented Minority; United States; United States National Institutes of Health; Woman; base; community based participatory research; community engaged research; community science; coronavirus disease; epidemiology study; innovation; interest; member; minority children; minority investigator; novel; operation; population health; programs; recruit; service utilization; social stigma; transmission process; treatment research; vaccine development; virus culture; working group

PROJECT SUMMARY Overall The mission of the UAB CFAR is to support the conduct of cutting-edge research in basic science, therapeutics, prevention, community engaged research, and clinical manifestations and pathogenesis of HIV and related disorders. Five core facilities provide vital support for the Center's principal thematic areas of its scientific agenda. To optimize our CFAR operation, an intensive strategic planning process has established efficiencies through streamlining its cores from 7 to 5, taking full advantage of existing services provided by other centers on campus, outsourcing under-utilized services, and allowing for investments in new areas (Specific Aims workshops, Transplant Tissue Procurement Facility, and Ending HIV in Alabama SWG). The Center includes 185 members from over 30 divisions and departments within UAB. Over the last 4 years, the UAB CFAR has enabled research leading to FRB / total funding of $21M / $66M. The majority (62%) was newly obtained in this budget period; 57% of these are related to basic science, 18% to population health prevention and treatment research, 22% to behavioral epi and intervention research, and 3% to community engaged research. Since our last renewal, the center has increased the number of young investigators supported by training awards from 7 to 16 (14 women; 5 under-represented minorities, URMs) and invested $1.9M in new-investigator pilot awards yielding $25M in outside funding. Overall, for our ROI in pilot funding is 13:1 in new extramural grants awarded. The Center helped recruit 45 new HIV/AIDS investigators in the last 4 years (17 external, 28 new to HIV research), of whom 21 are women and 5 URMs. Across all cores the CFAR supported 61 unique, NIH-funded projects (FRB) and 404 other NIH-funded projects, of which 309 were HIV-specific resulting in over 1000 HIV publications, and in the garnering of strong Institutional support. Over the next 5 years we will: (1) Continue to enhance the productivity of ongoing research programs by enabling interdisciplinary research through the provision of critical shared resource facilities and administrative and fiscal management support to Center investigators (2) Use robust strategic planning methods to identify new research opportunities and priorities that align with existing CFAR programs and foster new research programs where none are in existence, but where faculty interest is evident; (3) Stimulate the entry of early stage and established faculty into HIV/AIDS research programs through mentoring programs for young investigators and through a robust, peer-reviewed Developmental Grants Program; (4) Provide a central focus for HIV/AIDS research activities at UAB that emphasize effective communication and collaboration among CFAR members with the wider HIV/AIDS research community; and (5) Promote faculty recruitment and program development in areas that reflect the ongoing evolution of HIV/AIDS research in Alabama, the United States, and around the world. The UAB CFAR will foster HIV/AIDS research that has high local, national, and international impact and in so doing will promote the NIH priorities of innovation and effectiveness in AIDS treatment and prevention.

项目摘要 全面的 UAB CFAR的任务是支持基础科学，治疗学，尖端研究的行为， 预防，社区参与研究，临床表现和艾滋病毒和相关的发病机理 疾病。五个核心设施为该中心的科学议程的主要主题领域提供了重要的支持。 为了优化我们的CFAR操作，密集的战略规划过程已通过 将其核心从7到5简化，充分利用校园其他中心提供的现有服务 外包利用不足的服务，并允许在新领域进行投资（特定的目标讲习班， 移植组织采购设施，在阿拉巴马州SWG中结束HIV）。该中心包括185名成员 来自UAB内30多个部门和部门。在过去的四年中，UAB CFAR启用了研究 导致FRB /总资金为2100万美元 / 6600万美元。大多数（62％）是在此预算期间新获得的； 其中有57％与基础科学有关，有18％与人口健康和治疗研究有关，22％ 行为EPI和干预研究，占社区参与研究的3％。自从我们上次续签以来 中心已将培训奖的年轻调查员数量从7增加到16个（14名妇女； 5个代表性不足的少数族裔，URMS），并向新投资人的飞行员奖投资了190万美元，获得了2500万美元 外部资金。总体而言，对于我们的飞行员资金投资回报率是13：1，在新的外部赠款中授予。中心帮助 在过去的4年中，新兵45名新的艾滋病毒/艾滋病调查员（17个外部，28个新的艾滋病毒研究），其中21个是 妇女和5个URM。在所有内核中 NIH资助的项目，其中309个特定于HIV，导致了1000多个HIV出版物，并获得了收获 强大的机构支持。在接下来的5年中，我们将： （1）继续通过跨学科研究来增强正在进行的研究计划的生产率 通过提供关键的共享资源设施以及行政和财政管理支持 中心研究人员（2）使用强大的战略规划方法来确定新的研究机会和 与现有CFAR计划保持一致的优先级和培养不存在的新研究计划， 但是，有明显的教师利益的地方； （3）刺激早期阶段的进入，并建立了教师进入艾滋病毒/艾滋病 通过为年轻调查人员提供指导计划的研究计划，并通过强大的同行评审 发展赠款计划； （4）为UAB的艾滋病毒/艾滋病研究活动提供了一个核心重点 强调CFAR成员与更广泛的艾滋病毒/艾滋病研究的有效沟通和协作 社区; （5）在反映持续的领域促进教师招聘和计划发展 艾滋病毒/艾滋病研究在阿拉巴马州，美国和世界各地的演变。 UAB CFAR将培养具有较高本地，国家和国际影响力的艾滋病毒/艾滋病研究 做将促进NIH在艾滋病治疗和预防方面的创新和有效性的优先事项。