Project 1: Wildfire impacts on birth and developmental outcomes in a rural state
项目 1:野火对农村地区出生和发育结果的影响
基本信息
- 批准号:10362584
- 负责人:
- 金额:$ 23.13万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-04-01 至 2025-02-28
- 项目状态:未结题
- 来源:
- 关键词:AccountingAchievementAcuteAddressAdmission activityAge-MonthsAir PollutantsAir PollutionAmericanAreaBirthBirth CertificatesBirth WeightCardiovascular systemCenters for Population HealthChildChild HealthChildhoodChronicClinicCollaborationsCommunicationCommunitiesComputerized Medical RecordCookstoveCountryDataData SourcesDeath CertificatesDevelopmentEducationElectronic Health RecordEnsureEnvironmental ExposureEnvironmental ImpactEventExposure toFederally Qualified Health CenterFetal DeathFetal Mortality StatisticsFire - disastersFrequenciesFutureGestational AgeHealthHealth systemHealthcare SystemsHeatingHospitalsHouseholdHumanImpairmentIncomeIndividualIndustryInfantInfant DevelopmentInfant MortalityInterventionInvestigationKnowledgeLinkLiteratureLow Birth Weight InfantMeasuresMedical centerModelingModificationMontanaMothersNeighborhoodsNeonatal Intensive Care UnitsOutcomeParticipantParticulateParticulate MatterPopulationPregnancyPremature BirthPublic HealthRecordsResearchResource DevelopmentResourcesRiskRuralRural CommunityScienceSeasonsServicesSeveritiesSmall for Gestational Age InfantSocioeconomic StatusSourceSpontaneous abortionSurveysTestingTimeWildfireWood stoveWorkautism spectrum disorderclimate changeearly childhoodepidemiology studyexperiencefine particlesfire fighterforesthealth care service organizationimprovedinterestmortalityneurodevelopmentnovelpredictive modelingprematureresidenceresiliencerespiratory healthrural areasocial capitalspatiotemporaltherapy designtrendurban area
项目摘要
Project Summary/Abstract
Wildfires are increasing in frequency, severity, and duration. Climate change and readily-available fuel sources
ensure the trend toward increased fire frequency and severity will persist. Moreover, wildfires are not simply a
short-term phenomenon; the duration of fire seasons has increased dramatically over the last three decades.
Research on the health impacts of wildfires has to date emphasized respiratory health and, to a lesser degree,
cardiovascular endpoints. Although a growing body of literature has demonstrated that urban air pollution,
specifically PM2.5, is linked to increased risk of miscarriage, lower birth weight, prematurity, being small for
gestational age, and developmental conditions such as autism, little research has evaluated influence of
wildfires on birth and development in the U.S. Of note, none of this work has been performed in rural areas,
which have a unique profile of exposures throughout the year. An urgent need exists to understand impacts to
inform strategies for community- and individual-level interventions. We will combine state-of-the-art air pollutant
exposure assessment, birth certificate and fetal and infant mortality data, and electronic health records (EHR)
to quantify the risk to infants associated with wildfire exposures during pregnancy and identify factors that
promote resilience. The association between participant residence-specific estimates of wildfire exposure,
overall and by trimester, and birth outcomes in Montana between 2000 and 2017, accounting for exposures
occurring throughout the year, will be investigated. Specific outcomes include birth weight, low birth weight
status, and small for gestational age status; gestational age at birth and preterm birth status; neonatal intensive
care unit admission; fetal death; and infant mortality. EHR will be used to evaluate the impact of wildfire
exposures on development in infants born in western Montana in the Providence and Community Medical
Center health care organizations between 2012 and 2017. Specifically, we will investigate the effect of wildfire-
related PM2.5 exposures on developmental milestone achievement at 2, 4, and 6 months of age. To inform the
development of efficacious, practical, and sustainable interventions, we will examine potential effect
modification by: individual-level factors, such as maternal education and household income, and community
resilience promoting resources, including neighborhood socioeconomic status, social capital, and information
and communication capacity. The successful conduct of the proposed research will build capacity for
sophisticated spatio-temporal modeling of wildfire-associated air pollutant exposure and expanded and more
comprehensive studies of neurodevelopmental impacts of environmental exposures. The proposed project will,
for the first time, quantify the impacts of wildfires on birth and development in rural areas and determine
resources that confer resilience to these effects. Most importantly, it will inform future interventions designed to
mitigate the impacts of this ever-growing threat to public health.
项目概要/摘要
野火的频率、严重程度和持续时间都在增加。气候变化和现成的燃料来源
确保火灾频率和严重程度增加的趋势将持续下去。此外,山火不仅仅是一场
短期现象;过去三十年来,火灾季节的持续时间急剧增加。
迄今为止,关于野火对健康影响的研究一直强调呼吸系统健康,并且在较小程度上强调了
心血管终点。尽管越来越多的文献表明城市空气污染
特别是 PM2.5,与流产、低出生体重、早产、身材矮小的风险增加有关
胎龄和自闭症等发育状况的影响,很少有研究评估
野火对美国出生和发展的影响值得注意的是,这些工作都没有在农村地区进行过,
全年都有独特的风险敞口。迫切需要了解对
为社区和个人层面的干预策略提供信息。我们将结合最先进的空气污染物
暴露评估、出生证明、胎儿和婴儿死亡率数据以及电子健康记录 (EHR)
量化怀孕期间与野火暴露相关的婴儿风险,并确定影响因素
促进复原力。参与者对野火暴露的特定居住地估计之间的关联,
蒙大拿州 2000 年至 2017 年间的整体情况和按三个月计算的出生结果(考虑了暴露情况)
全年发生的情况,将受到调查。具体结果包括出生体重、低出生体重
状况和小于胎龄状况;出生胎龄和早产状况;新生儿强化
入住护理单位;胎儿死亡;和婴儿死亡率。 EHR将用于评估野火的影响
普罗维登斯和社区医疗中心蒙大拿州西部出生的婴儿发育暴露情况
2012 年至 2017 年间中心医疗机构。具体来说,我们将调查野火的影响-
相关 PM2.5 暴露对 2、4 和 6 个月龄发育里程碑成就的影响。通知
制定有效、实用和可持续的干预措施,我们将研究潜在的效果
修改依据:个人层面的因素,例如孕产妇教育和家庭收入以及社区
复原力促进资源,包括社区社会经济地位、社会资本和信息
和通讯能力。拟议研究的成功进行将建设能力
与野火相关的空气污染物暴露的复杂时空模型以及扩展等
环境暴露对神经发育影响的综合研究。拟议的项目将,
首次量化野火对农村地区出生和发展的影响,并确定
赋予抵御这些影响的资源。最重要的是,它将为未来的干预措施提供信息
减轻这一日益严重的公共卫生威胁的影响。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Erin O'Brien Semmens其他文献
Erin O'Brien Semmens的其他文献
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{{ truncateString('Erin O'Brien Semmens', 18)}}的其他基金
Project 1: Wildfire impacts on birth and developmental outcomes in a rural state
项目 1:野火对农村地区出生和发育结果的影响
- 批准号:
10619521 - 财政年份:2020
- 资助金额:
$ 23.13万 - 项目类别:
Project 1: Wildfire impacts on birth and developmental outcomes in a rural state
项目 1:野火对农村地区出生和发育结果的影响
- 批准号:
10132359 - 财政年份:2020
- 资助金额:
$ 23.13万 - 项目类别:
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