Biolibrary and Pathology

生物图书馆和病理学

• 批准号: 10205354
• 负责人: George Victor Thomas
• 金额: $ 29.91万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10205354
• 关键词: Accreditation; American; Animals; Applications Grants; Award; Biocompatible Materials; Biological; Blood; Body Fluids; Case Study; Client; Clinical; Clinical Data; Clinical Laboratory Improvement Amendments; Clinical Research; Clinical Trials; Clinics and Hospitals; Collection; Communities; Consent; Consult; Consultations; DNA; Data; Databases; Development; Disease; Education; Ensure; Equipment and supply inventories; Experimental Designs; Fishes; Fluorescent in Situ Hybridization; Formalin; Freezing; Funding; Genetic; Genetic Privacy; Goals; Grant; Guidelines; Health Insurance Portability and Accountability Act; Histology; Histopathology; Human; Image; Immunofluorescence Immunologic; Immunohistochemistry; In Situ; Institutes; Institutional Policy; Institutional Review Boards; International; Laws; Link; Malignant Neoplasms; Manuscripts; Microtome - medical device; Oregon; Outcomes Research; Paraffin Embedding; Pathologist; Pathology; Patients; Policies; Preparation; Privacy; Proteins; RNA; Regulation; Research; Research Personnel; Resource Sharing; Resources; Rodent; Saliva; Sampling; Security; Services; Societies; Specific qualifier value; Specimen; Stains; System; Testing; Time; Tissue Banks; Tissue Stains; Tissue imaging; Tissues; animal tissue; biobank; college; common rule; cryostat; data repository; demographics; experience; human tissue; member; nonhuman primate; repository; research study; tissue preparation

BIOLIBRARY & PATHOLOGY SHARED RESOURCE Directors: Devon Kelly, M.S. and George Thomas, M.D ABSTRACT/PROJECT SUMMARY The Knight Cancer Institute (Knight) sponsored BioLibrary & Pathology Shared Resource brings together tissue collection, processing, clinical annotation, and histopathology services into a single core. The unit provides members with: 1) a repository of well-annotated human tissue, blood and saliva, 2) a database of annotated clinical variables including patient demographics, treatments and clinical outcomes; research and clinical trial participation; genetic profiles, research analyses and specimen imaging, 3) tailored data in the form of client-specified case reports, 4) pathology services for studies on human and animal tissues, including cryostat sectioning, paraffin-embedding, microtome-sectioning, histochemical staining, immunohistochemistry, immunofluorescence and fluorescent in situ hybridization, 5) support in producing high quality RNA and DNA samples from both frozen and fixed specimens, and 6) pre-award consulting for preparation of grant and other funding applications. The BioLibrary & Pathology Shared Resource is accredited through the College of American Pathologists (CAP) and is Clinical Laboratory Improvement Amendments (CLIA) certified. It is staffed with members who have decades of combined experience in handling samples from small animals and human to ensure that tissues are properly prepared to meet the various needs of the research community, both for immediate analyses as well as long-term storage and use.

生物图书馆和病理学共享资源 董事：Devon Kelly，理学硕士和乔治·托马斯医学博士 摘要/项目摘要 奈特癌症研究所 (Knight) 赞助的生物图书馆和病理学共享资源汇集了 将组织采集、处理、临床注释和组织病理学服务整合为一个核心。单位 为成员提供：1) 一个详细注释的人体组织、血液和唾液的存储库，2) 一个数据库 带注释的临床变量，包括患者人口统计、治疗和临床结果；研究 和临床试验参与；遗传图谱、研究分析和标本成像，3) 定制数据 以客户指定的病例报告的形式，4）用于人类和动物组织研究的病理学服务， 包括低温切片、石蜡包埋、切片机切片、组织化学染色、 免疫组织化学、免疫荧光和荧光原位杂交，5) 生产支持 来自冷冻和固定样本的高质量 RNA 和 DNA 样本，以及 6) 授标前咨询 准备赠款和其他资助申请。生物图书馆和病理学共享资源是 通过美国病理学家学院 (CAP) 认证，是临床实验室改进 修正案（CLIA）认证。其成员均拥有数十年的综合经验 处理来自小动物和人类的样本，以确保组织得到适当的准备以满足 研究界的各种需求，包括即时分析以及长期存储和 使用。