Development Research Program

发展研究计划

• 批准号: 10208811
• 负责人: ELIZABETH A GRIMM
• 金额: $ 8.94万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-16 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10208811
• 关键词: Authorization documentation; Award; Bioinformatics; Biology; Biometry; Budgets; Clinical; Clinical Research; Collaborations; Cutaneous Melanoma; Data; Data Analyses; Development; Environment; Evaluation; Faculty; Funding; Funding Agency; Future; Grant; Guidelines; Immune response; Immunotherapy; Incidence; Laboratories; Medical center; Methods; Minority; Monitor; Morbidity - disease rate; Outcome; Patient-Focused Outcomes; Patients; Peer Review; Philanthropic Fund; Pilot Projects; Postdoctoral Fellow; Prevention; Program Research Project Grants; Research; Research Design; Research Personnel; Research Project Grants; Resources; Role; Sampling; Scientist; Site; Societies; Testing; Texas; Tissues; University of Texas M D Anderson Cancer Center; Uveal Melanoma; Woman; base; design; feasibility testing; flexibility; follow-up; high reward; high risk; innovation; interest; melanoma; novel; parent grant; programs; research and development

Developmental Research Program: Project Summary/Abstract This SPORE in Melanoma Developmental Research Program (DRP) serves to identify and fund pilot projects that take maximum advantage of new research breakthroughs and novel ideas that may eventually reduce the incidence and morbidity or increase the survival of patients with melanoma. Progress in understanding of melanoma biology and the role of immune response in melanoma patient outcomes has led to substantial advances in both targeted and immunotherapies for melanoma patients, and much promise is held for immediate future advances. Therefore, we are particularly interested in leveraging novel ideas from investigators with a variety of expertise in this DRP, and providing seed money for testing creative hypotheses and obtaining preliminary data for projects that are not supported by current or alternative funding sources. High risk/high reward pilot projects are especially prioritized, and applications from women and minority or underserved investigators are strongly encouraged. The available DRP funds include the required $50,000 annually throughout the duration of the SPORE award, as well as an annual contribution of up to $100,000 from institutional “matching funds,” for a total of $150,000 per year. Applications for SPORE DRPs are solicited annually, with an aim to fund at least 3 one-year awards of up to $50,000 each, with the possibility of ongoing support for a second year award of $50,000 if requested and approved based on acceptable progress. Philanthropic funds will also be utilized if available to support high quality proposals. Projects that provide a “pipeline” of additional value to the main SPORE projects or that support other new or concurrent melanoma grants are welcomed.

发展研究计划：项目摘要/摘要 黑色素瘤发展研究计划（DRP）的这个孢子用于确定和资助试点项目 最大限度地利用新的研究突破和新的想法，最终可能减少 发病率和发病率或增加黑色素瘤患者的存活率。在了解 黑色素瘤生物学和免疫应答在黑色素瘤患者结局中的作用已经导致了大量的 黑色素瘤患者的靶向治疗和免疫治疗都取得了进展， 未来的进步。因此，我们特别感兴趣的是利用来自 在这个DRP中拥有各种专业知识的调查人员，并为测试创造性假设提供种子资金 以及为目前或其他资金来源不支持的项目获取初步数据。 高风险/高回报的试点项目尤其受到优先重视，妇女和少数民族或 大力鼓励服务不足的调查人员。可用的DRP资金包括所需的5万美元 在整个SPORE奖期间，每年提供一次，以及每年高达10万美元的捐款 从机构“配套资金”中拨款，每年共计15万美元。政府现正征集“孢子回收计划”的申请 每年，目的是资助至少3个一年期的奖项，每个奖项最高可达50，000美元，并有可能持续 如果根据可接受的进展提出请求并获得批准，则支持第二年的50 000美元奖励。 如果有慈善基金，也将用于支持高质量的提案。提供一个 对主要SPORE项目或支持其他新的或同时发生的黑色素瘤具有附加价值的“管道” 赠款是受欢迎的。