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Understanding Social Communication Abilities in Individuals with Alzheimer's Disease

了解阿尔茨海默病患者的社交沟通能力

基本信息

批准号：
10386890
负责人：
Eun Jin Paek
金额：
$ 15.32万
依托单位：
UNIVERSITY OF TENNESSEE HEALTH SCI CTR
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-04-15 至 2025-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10386890
关键词：
Adult Affect Alzheimer&apos s Disease Alzheimer&apos s disease related dementia American Amnesia Attention Caregiver Burden Caregivers Characteristics Cognition Cognitive Cognitive Science Communication Conflict (Psychology)Data Data Set Dementia caregivers Disease Elderly Exhibits Foundations Gestures Goals Health Professional Image Impaired cognition Impairment Individual Iowa Knowledge Label Language Language Tests Length Life Linguistics Literature Measures Memory Modality Nature Nerve Degeneration Nonverbal Communication Participant Patients Performance Population Process Production Property Quality of life Recommendation Research Resources Social Characteristics Social isolation Speech-Language Pathology Standardization System Techniques Tennessee Time Training and Education Triad Acrylic Resin Work base caregiver education cognitive ability cognitive testing design evidence base executive function experience implicit memory improved lexical rehabilitation management skills social social communication social engagement theories

项目摘要

Project summary Individuals with Alzheimer’s disease and related dementias (ADRD) and their caregivers experience significant challenges in daily conversations and social communication. Yet, it is less understood how these challenges can be effectively managed and what recommendations can be made with respect to the strategies for both individuals with ADRD and caregivers to optimize their optimal communication. The long-term objectives of the proposed study are to develop efficient management strategies and to hone caregiver training and education strategies for individuals with ADRD. Our proposed study will lay foundation to achieve these goals through an improved understanding of the characteristics and underpinning mechanisms of social communication deficits, namely audience design impairments in individuals with amnestic Alzheimer’s Disease (AD). Audience design is a key to successful social communication and involves speaker modulation of their utterances depending on the partner’s knowledge. The specific aims of the proposed research are: (1) to understand verbal and non- verbal audience design impairments in individuals with AD and healthy older adults, and (2) elucidate cognitive and linguistic substrates underlying the audience design skills in these populations. We will deploy an experimental paradigm using referential communication tasks to study communication in the lab with a high ecological validity that simulates aspects of natural communication in everyday life. During the task, a participant and an experimenter will solve a task that is highly dependent on interactive and dynamic communication. The participant will repeatedly describe a set of abstract images to the experimenter; the changing properties of the spoken and non-verbal communication over time can be used as a measure of the extent to which partners develop shared knowledge. The participant will also describe abstract images to different partners with different shared knowledge in multiparty conversational setting. Performance data obtained during the communication task will be analyzed to delineate how participants with AD tailor their language based on their partner’s perspectives. Following the referential communication task, a standardized language and cognitive test battery will be given to measure attention, memory, executive function, and language. The data set will be analyzed to determine what cognitive and/or linguistic factors significantly contribute to or associated with the observed audience design deficits. The multi-PI approach is designed to take advantage of complementary expertise in the techniques and theories of Cognitive Science and Speech- Language Pathology, and the resources unique to both Iowa and Tennessee.

项目概要阿尔茨海默病和相关痴呆症 (ADRD) 患者及其护理人员在日常对话和社交沟通中遇到重大挑战。然而，还是比较少了解如何有效管理这些挑战以及可以提出哪些建议制定针对 ADRD 患者和护理人员的策略优化他们的最佳沟通。拟议研究的长期目标是制定有效的管理策略并加强护理人员培训和教育 ADRD 患者的策略。我们提出的研究将为实现这些目标奠定基础通过更好地了解特征和基础机制来实现目标社会沟通缺陷，即个体的受众设计障碍遗忘性阿尔茨海默病（AD）。受众设计是成功社交的关键沟通，并涉及根据合作伙伴的说话者对他们的话语进行调制知识。本研究的具体目标是：（1）理解语言和非语言 AD 患者和健康老年人的言语受众设计障碍，以及 (2) 阐明这些受众设计技能背后的认知和语言基础人口。我们将使用参考通信任务部署一个实验范式在实验室中研究具有高生态有效性的交流，模拟自然的各个方面日常生活中的沟通。在任务期间，参与者和实验者将解决一个高度依赖于交互式和动态通信的任务。参与者将向实验者反复描述一组抽象图像；的属性的变化随着时间的推移，口头和非口头交流可以用来衡量沟通的程度。哪些合作伙伴开发共享知识。参与者还将描述抽象图像在多方对话环境中具有不同共享知识的不同合作伙伴。将分析通信任务期间获得的性能数据，以描述如何 AD 参与者根据伴侣的观点调整他们的语言。继将提供参考沟通任务、标准化语言和认知测试电池测量注意力、记忆力、执行功能和语言。将分析数据集确定哪些认知和/或语言因素显着影响或与之相关观察到的受众设计缺陷。多 PI 方法旨在利用认知科学和言语技术和理论的互补专业知识- 语言病理学，以及爱荷华州和田纳西州独有的资源。