Physiological Outcomes of Mind-Body Health Practices for Stress-Related Disorders

项目摘要 心血管对急性应激源的高反应性是创伤后应激(PTS)的常见症状。 综合心身健康实践已显示出治疗PTS和压力相关疾病的希望 精神错乱。其中许多综合练习包括呼吸控制性呼吸练习。心身 练习中经常使用一种强调缓慢深呼吸的调息法，作为镇静的一种策略 生理应激反应。Pranayam尚未被作为一种孤立的急性应对反应进行研究 面对创伤提醒。关于这一策略在平息情绪方面的实际效果，我们知之甚少 高度觉醒症状，尤其是心血管反应性升高。Pranayam已经被普遍探索过了 作为一种平静压力反应的方法，尽管不是在创伤的背景下，也不是作为一种应对措施而孤立 处理急性危难的策略。确定有效的方法来平息心血管对创伤的反应 提醒是重要的，因为夸大的心血管反应性与以后的风险有关 心血管疾病。在这个项目中，我们检查了1)Pranayam在减少过度唤醒方面的有效性 对创伤提醒的反应，无论是在自发的日常使用中还是在指导的实验室任务中，2)水平是否更高 内感意识的增强普兰那扬在降低过度觉醒反应方面的效果，3)如果 情绪调节技能在普兰雅姆使用和心血管反应性之间的关系中起中介作用。我们是 在130名女性性创伤幸存者中进行了这项研究。我们会把Pranayam比作 基于认知的应对策略，认知重新评估，以确定普拉纳坦是否是一种有效的镇静手段 创伤提示引起的高度觉醒。高度唤醒将由心血管测量的唤醒来确定， 包括心率、心率变异性和血压。通过隔离和明确测试深呼吸 Pranayam，我们可以确定Pranayam是否是身心健康干预可能通过的机制 发挥他们的作用。这一简单、节俭的策略可以被强调为应对 可能时间有限或可用资源很少的幸存者。该项目作为一个培训工具，通过 申请者可以朝着她的长期研究目标努力，她的研究目标是检查心身如何整合 健康干预可能会影响创伤暴露人群的应激反应。这个项目是下一个 申请人更广泛的职业研究目标的阶段，即通过以下方式确定和理解机制 哪种身心干预措施可以降低心血管风险，特别是对处于 增加患心血管疾病的风险。

Project Summary Heightened cardiovascular reactivity to acute stressors is a common symptom of posttraumatic stress (PTS). Integrative mind-body health practices have shown promise for the treatment of PTS and stress-related disorders. Many of these integrative practices include pranayam, the practice of controlled breathing. Mind-body practices often use a type of pranayam that emphasizes slowed, deep breathing, as a strategy to calm physiological stress reactions. Pranayam has yet to be studied as an isolated, acute coping response when confronted with trauma reminders. Little is known about how well this strategy actually works to calm one’s hyperarousal symptoms, particularly elevated cardiovascular reactivity. Pranayam has been explored generally as a method of calming the stress response, though not in the context of trauma and not isolated as a coping strategy for managing acute distress. Identifying effective methods to calm cardiovascular responses to trauma reminders is important given the association of exaggerated cardiovascular reactivity with later risk for cardiovascular disease. For this project, we examine 1) how effective pranayam is at reducing hyperarousal in response to trauma reminders, both in spontaneous daily use and in a directed lab task, 2) whether higher levels of interoceptive awareness increase the effect that pranayam has on lowering hyperarousal reactions, 3) if emotion regulation skills mediate the relationship between pranayam use and cardiovascular reactivity. We are conducting this study within a sample of 130 female sexual trauma survivors. We will compare pranayam to a cognitive-based coping strategy, cognitive reappraisal, to determine if pranayam is an effective means of calming trauma cue-induced hyperarousal. Hyperarousal will be determined by cardiovascular measures of arousal, including heart rate, heart rate variability, and blood pressure. By isolating and explicitly testing deep breathing pranayam, we can determine if pranayam is the mechanism through which mind-body health interventions may exert their effects. This simple, parsimonious strategy can be emphasized as a primary coping strategy for survivors who may have limited time or few available resources. This project serves as a training vehicle through which the applicant can work towards her long-term research goals of examining how integrative mind-body health interventions may impact the stress response in trauma-exposed populations. This project is the next phase of the applicant’s broader career research goal of identifying and understanding the mechanisms through which mind-body interventions can reduce cardiovascular risk, particularly for trauma survivors who are at increased risk for cardiovascular disease.