The Alzheimer's Disease Clinical and Translational Research (ADCTR) Training Program

这是阿尔茨海默病临床和转化研究（ADCTR）培训的新建议 伦斯勒理工学院（RPI）与伊坎医学院合作的项目 Sinai（ISMMS）.我们的目标是增加三所学校学生之间的互动 （建筑，工程和科学）和四个博士授予部门（生物医学工程， 生物科学，化学工程和化学）以及四个研究所范围的中心（中心 生物技术和跨学科研究（CBIS），照明研究中心（LRC），数据研究所 探索和应用（IDEA）和塞韦里诺技术创业中心）以及 RPI计算机科学系和Lally管理学院。该罗纳德M.洛布中心 阿尔茨海默病在伊坎医学院和行业合作伙伴将提供短期 AD和AD相关痴呆症的培训/研究项目。该培训计划将为学员提供一个 对阿尔茨海默病研究的跨学科，临床和转化性质的敏锐理解 以及相关的痴呆症，它是如何依赖于科学和工程学的基础， 导致创新的新科学学科和技术，如何将其应用于临床环境， 商业产品是如何开发的。这些项目的教师积极参与研究 项目包括：1）阿尔茨海默病的药物和非药物干预 疾病和神经退行性疾病; 2）生物标志物和成像;和3）结构生物学 蛋白质折叠/tau.培训计划的主要方面将包括：[1]一套四门课程， 最大限度地提高关键学科的教学培训; [2]一个核心课程，题为“阿尔茨海默氏症的观点” 疾病研究”，将采取由所有学员; [3]一系列研讨会和研究座谈会，将建立 在RPI及其临床和行业合作伙伴的校园范围内的计划; [4]一个学生运行的研讨会计划， 学员向同行和培训教师展示他们的研究; [5]培训负责任的行为 研究; [6]联合监督（每个受训者至少有2名跨学科导师）和多学科 博士论文委员会成员建筑、科学和工程方面的论文工作; [7]工业 和/或临床实习; [8]海报展示和参加CBIS年会， LRC行业合作伙伴计划; [9]创业和商业翻译培训;以及[10]年度 在阿尔茨海默病和相关痴呆症的当代研究务虚会上，学员和其他人 在校园里与该领域的外部研究人员互动。执行委员会将确保受训人员 符合计划要求，代表性不足的少数民族招聘委员会（URM）将积极 参与，识别和招募多样化的学生群体进入该计划。除了六个实习生名额 伦斯勒将每年资助两名学院学员。

This is a new proposal for the Alzheimer's Disease Clinical and Translational Research (ADCTR) Training Program at Rensselaer Polytechnic Institute (RPI) in collaboration with the Icahn School of Medicine at Mount Sinai (ISMMS). Our objectives are aimed at increased interaction among students from the three schools (Architecture, Engineering and Science) and four PhD granting departments (Biomedical Engineering, Biological Sciences, Chemical Engineering and Chemistry) as well as four Institute-wide centers (Center for Biotechnology and Interdisciplinary Studies (CBIS), Lighting Research Center (LRC), Institute of Data Exploration and Application (IDEA) and Severino Center for Technological Entrepreneurship) as well as the Department of Computer Science and the Lally School of Management at RPI. The Ronald M. Loeb Center for Alzheimer's Disease at Icahn School of Medicine at ISMMS and industry partners will provide short term training/research projects in AD and AD-related dementias. This Training Program will provide trainees with a keen understanding of the interdisciplinary, clinical and translational nature of research on Alzheimer's disease and related dementias, how it depends on fundamental underpinnings of both science and engineering, how it leads to innovative new scientific disciplines and technologies, how it can be applied to clinical settings, and how commercial products are developed. Faculty from these programs are actively involved in research programs spanning the following: 1) pharmacologic and non-pharmacologic interventions for Alzheimer's disease and neurodegenerative disease; 2) biomarkers and imaging; and 3) structural biology of protein folding/tau. Key aspects of the training program will include: [1] a set of four courses that will maximize didactic training among the key disciplines; [2] a core course entitled “Perspectives in Alzheimer's Disease Research” that will be taken by all trainees; [3] a seminar series and research symposia that will build on campus-wide programs at RPI and its clinical and industry partners; [4] a student-run seminar program, in which trainees present their research to their peers and training faculty; [5] training in responsible conduct of research; [6] joint supervision (at least 2 mentors spanning disciplines per trainee) and a multidisciplinary thesis committee membership for Ph.D. thesis work in architecture, science and engineering; [7] industrial and/or clinical externships; [8] poster presentation and participation in the annual meeting of the CBIS and LRC Industry Partners Program; [9] entrepreneurship and commercial translation training; and [10] an annual retreat in contemporary research in Alzheimer's Disease and related dementias at which trainees and others on campus interact with outside researchers in the field. An Executive Committee will ensure that trainees satisfy Program requirements and an Underrepresented Minority Recruitment (URM) Committee will actively engage in, identify and recruit a diverse student population into the program. In addition to the six trainee slots per year proposed herein, Rensselaer will support two Institute trainees per year.