ASU Faculty Enhancement: Wastewater-based epidemiology: relevant health metrics in Tribal communities.

亚利桑那州立大学教师增强：基于废水的流行病学：部落社区的相关健康指标。

• 批准号: 10223677
• 负责人: Otakuye Conroy-Ben
• 金额: $ 15.48万
• 依托单位: INTER TRIBAL COUNCIL OF ARIZONA, INC.
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-23 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10223677
• 关键词: Address; Administrator; Agreement; Area; Arizona; Award; Bacteria; Biological; Chemicals; Collection; Communicable Diseases; Communities; Coronavirus; Data; Development; Diabetes Mellitus; Engineering; Epidemiologic Monitoring; Ethics; European; Exposure to; Faculty; Future; Goals; Health; Health Benefit; Health Status; Human; Human Resources; Immunization; Indian reservation; Infrastructure; Institutional Review Boards; Investments; Knowledge; Measures; Mentors; Mentorship; Native American Research Center for Health; Perception; Pharmaceutical Preparations; Population; Protocols documentation; Public Health; Qualitative Research; Recommendation; Research; Research Personnel; Resources; Rural; Sampling; Substance abuse problem; Surveys; System; Training; Tribes; Universities; Virus; Waste Products; Water; Work; career; college; contaminated water; coronavirus disease; data dissemination; epidemiology study; experience; faculty mentor; gut microbiome; health disparity; indigenous community; intertribal; member; metropolitan; novel; pollutant; population health; professor; responsible research conduct; skills; tool; tribal community; tribal health; tribal leader; tribal member; wastewater epidemiology; wasting

PROJECT SUMMARY Wastewater-based epidemiology (WBE) is a powerful tool that can measure population health in communities with centralized sewer treatment systems and is particularly relevant for Tribes who wish to assess health disparities such as COVID and substance abuse. In WBE, chemical metabolites, bacteria and viruses, and other health indicators are measured in excreted human waste products in wastewater. The wastewater flow rate and population load into the sewershed allow for calculation of community-level human health indicators present in water. WBE has not been documented in Tribal communities prior to the PI’s efforts, and there are knowledge gaps related to the execution, acceptability, and applicability of this tool to assess Tribal population health. Our specific aims are to (1) develop a framework for conducting responsible WBE research and surveillance in Tribal communities, which will address data sovereignty, Tribal sewer infrastructure and personnel, and handling of environmental biospecimens; (2) assess the perceptions of using WBE by Tribal leaders, health administrators, and community members through surveys; and (3) determine and quantify relevant health metrics that can be measured by WBE, including infectious disease, pollutant exposure, the gut microbiome, and substance abuse. This faculty enhancement award under ITCA’s NARCH XI will provide directed mentorship and training to the PI from ITCA staff. This collaborative project will develop research capacity for ITCA, partner Tribes in Arizona and the faculty member through collection of preliminary data, leading to development of larger projects with ITCA and the partner intertribal consortia for future WBE studies.

项目总结