Developmental Research Project Program

实验研究项目概要 发展研究项目计划（DRPP）将支持扩大的研究人员队伍， 在INBRE IV下的HiSREP网络，大大扩大了能力，从而扩大了机会， 在夏威夷进行生物医学研究。在机构间可持续发展评估第三阶段取得成功的基础上， 在三个主要的本科院校（PUI）有前途的初级研究者（JIs），INBRE IV的DRPP将 此外，还提供多种竞争性供资机制，为各级调查人员提供机会， 更丰富的专业发展计划，更广泛的，有组织的访问核心设施，仪器仪表和 生物信息学/生物统计学支持。除了在我们的PUI中识别新的JI之外，新的竞争性 资助机制将是：试点项目，新举措，合作赠款和教学博士后 奖学金。对于所有的赠款，将鼓励合作;但是，对于合作赠款，优先 PUI研究者和R1领导机构的职业中期或高级联合提案 作为综合研究团队的一部分。将所有研究与两个主题联系起来，自然 产品和分子医学，将强调，特别是通过提供独特的资源， 如生物储存库，和程序性的专业知识，如UH癌症中心天然产品和 实验治疗学（NPET）计划。对于获奖者，期望和成果将以 科学和职业指导计划，由PUI和CC教师的教师-学者模式平衡， 教学要求很高的地方。这将与透明的调查员、项目和 行政评估，导致建设性的交流和响应行动计划。最后，A强 牵头机构的支助作用是提供资源（赠款管理、核心工具 设施、组织和动物工作、生物信息学、生物统计学）。 DRPP将通过三个具体目标实现其目标：（1）提供催化资金， 在HiSREP网络中的研究人员范围内的新兴研究;（2）提供多方面的 指导和专业发展计划，以新兴的调查;和（3）支持和扩大 核心设施

DEVELOPMENTAL RESEARCH PROJECT PROGRAM SUMMARY The Developmental Research Project Program (DRPP) will support an expanded cadre of investigators in the HiSREP network under INBRE IV, substantially expanding, in turn, the capacity and hence opportunity for biomedical research in Hawaii. Building on the success in INBRE III where the DRPP focused support on promising junior investigators (JIs) at three primarily undergraduate institutions (PUIs), DRPP in INBRE IV will additionally offer multiple competitive funding mechanisms with opportunity for investigators at all levels, a richer program in professional development, and wider, organized access to core facilities, instrumentation and bioinformatics / biostatistics support. In addition to identification of new JIs at our PUIs, the new competitive granting mechanisms will be: Pilot Projects, New Initiatives, Collaborative Grants and Teaching-Postdoctoral Fellowships. For all of the grants, collaborations will be encouraged; however, for Collaborative Grants, priority will be given for joint proposals from a PUI investigator and a R1 Lead Institution mid-career or senior investigator as part of an integrated research team. Connection of all research to the two themes, Natural Products and Molecular Medicine, will be emphasized, particularly through availability of unique resources, such as biorepositories, and programmatic expertise, such as the UH Cancer Center Natural Products & Experimental Therapeutics (NPET) program. For awardees, expectations and outcomes will be guided by scientific and career mentoring plans, balanced by the teacher-scholar model for faculty at PUIs and CCs, where teaching demands are significant. This will be coupled to transparent investigator, project and administration assessments, leading to constructive exchange and responsive action plans. Lastly, a strongly supportive role for the lead institution is providing resource access (grant management, core instrument facilities, tissue and animal work, bioinformatics, biostatistics). DRPP will accomplish its objectives through three specific aims: (1) Provide catalytic funding to support emerging research across the spectrum of investigators in the HiSREP network; (2) Provide multifaceted mentoring and professional development programs to emerging investigators; and (3) Support and expand core facilities.