Social determinants of sleep and obesity: Disparities in African Americans

项目摘要/摘要 这项拟议的研究旨在通过促进健康的生活方式行为来减少与肥胖相关的健康差距。 在非裔美国人(AAs)中，考虑到与低体力活动相关的高疾病负担，在- 充足的睡眠和肥胖。为此，候选人将寻求了解社会背景因素是如何 通过使用定性访谈和现有的定量数据集来影响睡眠(K99)。获得的知识 将通知现有睡眠干预的适应和测试(MDACC IRB Proto- 编号2018-0568)(R00)。在K99阶段，应聘者将接受集中和强化的培训，包括 ING研讨会、课程、讲座和来自不同健康领域的知名专家的指导读物- 领带、安眠药和肥胖。两项研究将包括：(目标1)进行定性的深入访谈，以 阐明社会背景对睡眠的影响，同时征求反馈以适应睡眠干预 肥胖、久坐和睡眠不足的再生障碍性贫血成年人；以及(目标2)经验性测试因此- 社会背景因素、睡眠、体力活动和体重，使用一项正在进行的AAS研究的数据 (项目信念；美国癌症协会，RSG-17-158-01；PI：McNeill博士，导师)。最后，在R00期间 阶段将汇编在K99阶段中获得的知识以适应睡眠干预并测试其可行性， 在改善睡眠、增加体力活动和减少久坐方面的满意度和初步疗效 超重/肥胖、久坐和睡眠不足的再生障碍性贫血成年人的行为(目标3)。候选人是 根据他过去治疗心肌梗死的临床经验，他处于独特的地位来完成拟议的研究- Nia和他对AAS中的睡眠和肥胖的研究。睡眠干预是一种很有前途的创新 优化心理和身体健康以减少肥胖和癌症相关健康疾病的方法 计划生育--国家少数民族健康和健康差距研究所的研究重点。此外， 拟议的培训计划对于加快候选人向独立调查员的过渡至关重要 在开发文化知情干预措施以减少癌症健康差异方面拥有专注的专业知识 在AAA中。

PROJECT SUMMARY/ABSTRACT The proposed research aims to reduce obesity-related health disparities by promoting healthy lifestyle behav- iors among African Americans (AAs), given the high disease burdens associated with low physical activity, in- sufficient sleep, and obesity. To this end, the candidate will seek to understand how social contextual factors impact sleep by using qualitative interviews and an existing quantitative data sets (K99). Knowledge gained from the K99 phase will inform the adaptation and testing of an existing sleep intervention (MDACC IRB Proto- col #2018-0568) (R00). During the K99 phase, the candidate will receive focused and intensive training involv- ing workshops, courses, lectures, and directed readings from renowned experts in the fields of health dispari- ties, sleep medicine, and obesity. Two studies will include: (Aim 1) conducting qualitative in-depth interviews to elucidate social contextual influences on sleep, while soliciting feedback to adapt a sleep intervention among obese, sedentary, and short-sleeping AA adults; and (Aim 2) empirically testing the associations between so- cial contextual factors, sleep, physical activity, and body weight using data from an ongoing studies of AAs (Project FAITH; American Cancer Society, RSG-17-158-01; PI: Dr. McNeill, mentor). Lastly, during the R00 phase will compile the knowledge gained in the K99 phase to adapt a sleep intervention and test its feasibility, satisfaction, and preliminary efficacy in improving sleep, increasing physical activity, and decreasing sedentary behavior among overweight/obese, sedentary, and sleep-deprived AA adults (Aim 3). The candidate is uniquely positioned to complete the proposed research based on his past clinical experience in treating insom- nia and his research on sleep and obesity among AAs. The sleep intervention is a promising and innovative approach to optimizing psychological and physical wellness to reduce obesity and cancer-related health dis- parities – a research priority at the National Institute on Minority Health and Health Disparities. Furthermore, the proposed training plan will be critical in expediting the candidate’s transition to an independent investigator with focused expertise in developing culturally informed interventions to reduce cancer health disparities among AAs.