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中文摘要
翻译
摘要-行政核心 行政核心的职能是管理整个计划项目补助金(PPG), 资源调配,确保科学目标的顺利完成。核心监督 活动,并广泛管理资源核心和单个计划项目的预算, 必要的组织和后勤支持。此外,行政核心的一个核心作用是充当 通过促进和促进所有PPG之间的互动, 件.个别项目的主要负责人在科学规划和实施方面享有自主权, 项目一级,但预计将纳入行政和科学委员会的建议, 资源核心和咨询委员会。行政核心将推动各级计划的整合 通过有组织的、实施良好的管理,体现PPG的科学使命 结构和研究战略。 行政核心的广泛目标和中心目标是: 1.管理:管理总体计划目标和方向,以及计划之间的互动 组件;管理资源核心的使用;并监督质量控制、存储和共享 主数据. 2.沟通:沟通相关和基本信息,并促进互动 PPG的所有组成部分,包括与科学咨询委员会(SAB)的正式和非正式互动, 包括面对面和网络会议,研讨会计划,年度进展报告,年度 专题讨论会和一个专门的程序网站。 3.支持:提供全面的组织和后勤支持(包括财务管理) PPG的所有组件。 通过为PPG调查人员提供全面的计划/项目管理支持, 通过多种方式实现所有人员之间的互动,行政核心增强了 PPG研究人员为更好地了解黑色素瘤生物学做出实质性贡献。
英文摘要
SUMMARY- ADMINISTRATIVE CORE The function of the Administrative Core is to manage the overall Program Project Grant (PPG) to maximize resource deployment and ensure successful completion of the scientific objectives. The core oversees the activities and broadly manages the budgets of the resource core and individual program projects, providing organizational and logistical support as needed. In addition, a central role of the Administrative core is to act as the communication hub of this program project by promoting and facilitating interaction amongst all PPG components. Individual project PIs will have autonomy with regard to scientific planning and implementation at the project level, but will be expected to incorporate suggestions from the Administrative and Scientific Resource Cores and advisory committees. The Administrative Core will drive program integration at all levels and embody the scientific mission of the PPG through an organized and well-implemented management structure and research strategy. The broad aims and central goals of the Administrative Core are: 1. Management: Manage overall program objectives and directions, and interactions between program components; administer Resource Core usage; and oversee quality control, storage, and sharing of primary data. 2. Communication: Communicate relevant and essential information to and facilitate interaction amongst all PPG components, including formal and informal interaction with the Scientific Advisory Board (SAB), including in-person and web-ex meetings, a seminar program, annual progress reports, yearly symposia, and a dedicated program website. 3. Support: Provide over-arching organizational and logistical support (including financial management) for all components of the PPG. By providing PPG investigators with comprehensive program/project management support and facilitating interaction among all personnel through multiple means, the Administrative Core augments the ability of the PPG investigators to make substantive contributions to better understand melanoma biology.
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The impact of changes in chromatin architecture on cancer phenotypes and tumor progression
Project 1: The biochemical, topological and functional impact of cancer associated Ctcfmutations and their contribution to cancer
Project 1: The biochemical, topological and functional impact of cancer associated Ctcfmutations and their contribution to cancer
The impact of changes in chromatin architecture on cancer phenotypes and tumor progression
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